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Evidence for neurobehavioral risk phenotypes at birth
AbstractObservations of newborn behavior provide clinicians and researchers with a first description of the neurobehavioral organization of the...
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Rare genetic brain disorders with overlap** neurological and psychiatric phenotypes
Understanding rare genetic brain disorders with overlap** neurological and psychiatric phenotypes is of increasing importance given the potential...
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Heterogeneity of glycaemic phenotypes in type 1 diabetes
Aims/hypothesisOur study aims to uncover glycaemic phenotype heterogeneity in type 1 diabetes.
MethodsIn the Study of the French-speaking Society of...
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Cumulative effect of obesity phenotypes on body weight and body mass index
BackgroundObesity originates from an imbalance between energy intake and expenditure. Changes in energy intake components (satiation, postprandial...
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Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies
Genome-wide association studies (GWAS) provide biological insights into disease onset and progression and have potential to produce clinically useful...
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Different expression levels of interleukin-36 in asthma phenotypes
Interleukin (IL)-36 family is closely associated with inflammation and consists of IL-36α, IL-36β, IL-36γ, and IL-36Ra. The role of IL-36 in the...
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Clinical, physiological, and radiological different phenotypes of COPD patients
BackgroundCOPD is a heterogeneous lung disorder with multiple phenotypes and endotypes. This study aimed to identify the diverse clinical,...
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Thyroid autoimmunity in different phenotypes of polycystic ovary syndrome: a single-center experience
PurposePolycystic ovary syndrome (PCOS) has been associated with Hashimoto’s thyroiditis (HT) and 4 phenotypes have been described in this syndrome....
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Clinical Phenotypes of PCOS: a Cross-Sectional Study
This cross-sectional study examines the Doi-Alshoumer PCOS clinical phenotype classification in relation to measured clinical and biochemical...
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Five million nights: temporal dynamics in human sleep phenotypes
Sleep monitoring has become widespread with the rise of affordable wearable devices. However, converting sleep data into actionable change remains...
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Different pain phenotypes are associated with anti-Caspr2 autoantibodies
Autoantibodies against contactin-associated protein 2 (Caspr2) not only induce limbic autoimmune encephalitis but are also associated with pain...
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Personalized anti-reflux surgery: connecting GERD phenotypes in 690 patients to outcomes
BackgroundAnti-reflux operations are effective treatments for GERD. Despite standardized surgical techniques, variability in post-operative outcomes...
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Cognitive phenotypes in multiple sclerosis: map** the spectrum of impairment
BackgroundAvailable criteria for cognitive phenotypes in multiple sclerosis (MS) do not consider the severity of impairment.
Objectives ...
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Identifying novel acute pancreatitis sub-phenotypes using total serum calcium trajectories
BackgroundAcute pancreatitis (AP) has heterogeneous clinical features, and identifying clinically relevant sub-phenotypes is useful. We aimed to...
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Validation of Distinct Bladder Pain Phenotypes Utilizing the MAPP Research Network Cohort
Introduction and HypothesisAs interstitial cystitis/bladder pain syndrome (IC/BPS) likely represents multiple pathophysiologies, we sought to...
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Precision nutrition for targeting pathophysiology of cardiometabolic phenotypes
Obesity is a heterogenous disease accompanied by a broad spectrum of cardiometabolic risk profiles. Traditional paradigms for dietary weight...
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Characterizing Bone Phenotypes Related to Skeletal Fragility Using Advanced Medical Imaging
Purpose of ReviewSummarize the recent literature that investigates how advanced medical imaging has contributed to our understanding of skeletal...
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Association between obesity phenotypes and non-alcoholic fatty liver: a large population- based study
BackgroundThe aim of this study was to examine the association between different metabolic obesity phenotypes and the non-alcoholic fatty liver...
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Less common phenotypes of myelin oligodendrocyte glycoprotein antibody-related diseases in children deserve more attention
BackgroundTo facilitate the identification of less common clinical phenotypes of myelin oligodendrocyte glycoprotein antibody-associated disease...
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Phenotypes of osteoarthritis-related knee pain and their transition over time: data from the osteoarthritis initiative
BackgroundIdentification of knee osteoarthritis (OA) pain phenotypes, their transition patterns, and risk factors for worse phenotypes, may guide...
