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Pharmacological and Non-pharmacological Approaches for the Management of Neuropathic Pain in Multiple Sclerosis
Multiple sclerosis is a chronic inflammatory disease that affects the central nervous system and can cause various types of pain including ongoing...
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Pharmacological treatment strategies for antipsychotic-induced hyperprolactinemia: a systematic review and network meta-analysis
Antipsychotic-induced hyperprolactinemia (AP-induced HPRL) occurs overall in up to 70% of patients with schizophrenia, which is associated with...
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Mechanisms Underlying Non-Pharmacological Dementia Prevention Strategies: A Translational Perspective
Since develo** an effective treatment for Alzheimer’s disease (AD) has been encountered as a challenging task, attempts to prevent cognitive...
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The comparison of the effect of non-pharmacological pain relief and pharmacological analgesia with remifentanil on fear of childbirth and postpartum depression: a randomized controlled clinical trial
IntroductionChildbirth may be associated with psychological, social, and emotional effects and provide the background for women’s health or illness...
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Pharmacological and non-pharmacological interventions for irritability in autism spectrum disorder: a systematic review and meta-analysis with the GRADE assessment
BackgroundNumerous interventions for irritability in autism spectrum disorder (ASD) have been investigated. We aimed to appraise the magnitude of...
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Integrative non-pharmacological care for individuals at risk of rheumatoid arthritis
There is increasing knowledge in the recognition of individuals at risk for progression to rheumatoid arthritis (RA) before the clinical...
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Central Neuropathic Pain Syndromes: Current and Emerging Pharmacological Strategies
Central neuropathic pain is caused by a disease or lesion of the brain or spinal cord. It is difficult to predict which patients will develop central...
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Pharmacological Treatments for Presbyopia
Accommodation is the change in dioptric power of the eye. It is a dynamic process that allows focusing on an object at all distances. In order to...
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Pharmacological labour pain interventions: South African midwives’ perspective
BackgroundWomen of childbearing age feel great about giving birth, but the pain could be excruciating depending on their pain tolerances. Midwives...
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Non-pharmacological interventions for delirium in the pediatric population: a systematic review with narrative synthesis
BackgroundDelirium is a serious complication experienced by hospitalized children. Therefore, preventive management strategies are recommended for...
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Assessment of Innovative Pharmacological Targets in Schizophrenia
Purpose of reviewSchizophrenia is a disorder with an approximate prevalence of 1% associated with great impairments in daily life functioning and...
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Insomnia and Its Non-Pharmacological Management in Older Adults
Purpose of ReviewInsomnia, a sleep disorder involving difficulty falling, maintaining, or obtaining good quality sleep, is a common health complaint...
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Non-Pharmacological Treatment for Chronic Migraine
Purpose of ReviewChronic migraine (CM) affects a large proportion of the population and is a significant source of disability and lost productivity....
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Sarcoidosis with musculoskeletal manifestations: systematic review of non-pharmacological and pharmacological treatments
We aimed to summarise effects and use of non-pharmacological and pharmacological treatments for sarcoidosis with musculoskeletal manifestations. We...
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Pharmacological Management of Orofacial Pain
Orofacial pain is a category of complex disorders, including musculoskeletal, neuropathic and neurovascular disorders, that greatly affect the...
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Efficacy of pharmacological and non-pharmacological therapy on pain intensity and disability of older people with chronic nonspecific low back pain: a protocol for a network meta-analysis
BackgroundThe purpose of this network meta-analysis (NMA) is to investigate the efficacy of pharmacological and non-pharmacological therapy on pain...
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Mirvetuximab soravtansine in ovarian cancer therapy: expert opinion on pharmacological considerations
ImmunoGen developed mirvetuximab soravtansine as an antibody–drug conjugate comprising of a humanized anti-folate receptor—α (FRα) monoclonal...
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Efficacy of pain management strategies in adults with Amyotrophic Lateral Sclerosis (ALS): A Systematic Review
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscle weakness. Presence of pain in ALS patients is...
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Targeting Neurotransmitter Systems in Bipolar Disorder: A comprehensive Review of novel pharmacological approaches
Purpose of ReviewTo critically assess the efficacy of novel pharmacological interventions in managing manic or hypomanic episodes in adult patients...
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Pharmacological Treatments of Temporomandibular Disorders: A Systematic Review Including a Network Meta-Analysis
ObjectiveTemporomandibular disorders (TMD) comprise a cluster of conditions with a wide range of etiological factors that causes pain and discomfort...
