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The failure of biological treatment in axial spondyloarthritis is linked to the factors related to increased intestinal permeability and dysbiosis: prospective observational cohort study
BackgroundA significant number of patients with axial spondyloarthritis (axSpA) do not respond to biological therapy. Therefore, we decided to...
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Reduced fibrin clot permeability on admission and elevated E-selectin at 3 months as novel risk factors of residual pulmonary vascular obstruction in patients with acute pulmonary embolism
BackgroundResidual pulmonary vascular obstruction (RPVO) is common following pulmonary embolism (PE) but its association with fibrin clot properties...
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The relationship between peritoneal membrane permeability and dyspepsia in peritoneal dialysis patients
ObjectiveThe aim of this study is to determine whether there is a relationship between peritoneal membrane permeability and dyspepsia in peritoneal...
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Breaking the Barrier: The Role of Gut Epithelial Permeability in the Pathogenesis of Hypertension
Purpose of the ReviewTo review what intestinal permeability is and how it is measured, and to summarise the current evidence linking altered...
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Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
BackgroundIn acute respiratory distress syndrome (ARDS), respiratory drive often differs among patients with similar clinical characteristics....
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Bovine Colostrum in Increased Intestinal Permeability in Healthy Athletes and Patients: A Meta-Analysis of Randomized Clinical Trials
BackgroundIncreasing intestinal permeability causes chronic inflammation, which is one of the etiological factors of many diseases that presently...
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Schizophrenia endothelial cells exhibit higher permeability and altered angiogenesis patterns in patient-derived organoids
Schizophrenia (SCZ) is a complex neurodevelopmental disorder characterized by the manifestation of psychiatric symptoms in early adulthood. While...
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Capillary leak and endothelial permeability in critically ill patients: a current overview
Capillary leak syndrome (CLS) represents a phenotype of increased fluid extravasation, resulting in intravascular hypovolemia, extravascular edema...
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Paracellular permeability and tight junction regulation in gut health and disease
Epithelial tight junctions define the paracellular permeability of the intestinal barrier. Molecules can cross the tight junctions via two distinct...
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Association between blood-brain barrier permeability and changes in pulse wave velocity following a recent small subcortical infarct
Cerebral small vessel disease (cSVD) is associated with increased blood-brain barrier (BBB) permeability. We sought to evaluate whether arterial...
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Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review. Comment
In this letter to the Editor, the author reports his comment on the review article entitled “Gut microbiota, intestinal permeability, and systemic...
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Cerebral collaterals are associated with pre-treatment brain–blood barrier permeability in acute ischemic stroke patients
IntroductionTo investigate the relationship between collaterals and blood–brain barrier (BBB) permeability on pre-treatment MRI in a cohort of acute...
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Chlorogenic acid-optimized nanophytovesicles: a novel approach for enhanced permeability and oral bioavailability
BackgroundChlorogenic acid, a phenolic derivative, shows excellent pharmacological properties. However, poor lipidic solubility, permeability, and...
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Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease
BackgroundKawasaki disease (KD) is a pediatric systemic vasculitis characterized by endothelial cell dysfunction. Semaphorin 7A (Sema7A) has been...
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Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19
Endotheliopathy plays a role in the development of acute kidney and lung injury in COVID-19, probably due to inflammation, endothelial permeability,...
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Intestinal permeability in patients with IgA nephropathy and other glomerular diseases: an observational study
BackgroundA dysregulated ‘gut-kidney axis’ may contribute to immunoglobulin A nephropathy (IgAN). We studied whether IgAN patients have disturbed...
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Wall permeability on magnetic resonance imaging is associated with intracranial aneurysm symptoms and wall enhancement
ObjectivesWall remodeling and inflammation accompany symptomatic unruptured intracranial aneurysms (UIAs). The volume transfer constant ( K trans ) of...
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The glycocalyx as a permeability barrier: basic science and clinical evidence
Preclinical studies in animals and human clinical trials question whether the endothelial glycocalyx layer is a clinically important permeability...
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Ameliorative Effects of Larazotide Acetate on Intestinal Permeability and Bacterial Translocation in Acute Pancreatitis Model in Rats
BackgroundIntestinal barrier dysfunction in acute pancreatitis (AP) may progress to systemic inflammatory response syndrome (SIRS) and multi-organ...
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The effect of an acute aspirin challenge on intestinal permeability in healthy adults with and without prophylactic probiotic consumption: a double-blind, placebo-controlled, randomized trial
BackgroundHealthy individuals may experience increases in intestinal permeability after chronic or acute use of non-steroidal anti-inflammatory...
