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The influence of dexmedetomidine added to ropivacaine for transversus abdominis plane block on perioperative neurocognitive disorders after radical colorectal cancer surgery: randomized, double-blind, controlled trial
ObjectivePerioperative Neurocognitive Disorders (PND) is a common neurological complication after radical colorectal cancer surgery, which increases...
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MiR-214-3p Prevents the Development of Perioperative Neurocognitive Disorders in Elderly Rats
ObjectiveThis study aimed to identify microRNAs (miRNAs) involved in the development of perioperative neurocognitive disorders (PND).
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Perioperative neurocognitive disorder changes in elderly diabetes patients within 30 days after surgery: a retrospective cohort study
BackgroundPerioperative neurocognitive disorders (PND) are a common central nervous system complication that predominantly affects the elderly. PND...
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Dexmedetomidine nasal administration improves perioperative sleep quality and neurocognitive deficits in elderly patients undergoing general anesthesia
ObjectiveTo investigate the improvement of perioperative sleep quality and neurocognitive impairment in elderly patients under general anesthesia by...
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The potential link between obstructive sleep apnea and postoperative neurocognitive disorders: current knowledge and possible mechanisms
PurposeThis narrative review examines the current evidence on whether obstructive sleep apnea (OSA) is associated with postoperative delirium (POD)...
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Effects of xenon anesthesia on postoperative neurocognitive disorders: a systematic review and meta-analysis
The latest clinical trials have reported conflicting outcomes regarding the effectiveness of xenon anesthesia in preventing postoperative...
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Clinical literature on postoperative delirium and neurocognitive disorders: a historical systematic review
BackgroundSince the appearance of the first report on postoperative cognitive impairment in 1955, the number of papers focusing on perioperative...
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Risk factors and predictive value of perioperative neurocognitive disorders in elderly patients with gastrointestinal tumors
BackgroundThis study aims to investigate the risk factors of perioperative neurocognitive disorders (PNDs) mainly including postoperative cognitive...
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Hundred most cited articles in perioperative neurocognitive disorder: a bibliometric analysis
BackgroundIn line with aging populations and increased application of anesthesia and surgery, perioperative neurocognitive disorder (PND) has...
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Comparing analog and digital neurocognitive tests with older adults: a study of the ISPOCD battery vs. a digital test battery from Mindmore
BackgroundDelayed neurocognitive recovery and neurocognitive disorder are common postoperative complications among older adults. The assessment of...
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Involvement of KCa3.1 channel activity in immediate perioperative cognitive and neuroinflammatory outcomes
BackgroundPotassium channels (KCa3.1; Kv1.3; Kir2.1) are necessary for microglial activation, a pivotal requirement for the development of...
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Perioperative stroke
Ischaemic or haemorrhagic perioperative stroke (that is, stroke occurring during or within 30 days following surgery) can be a devastating...
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Overview of Physical, Neurocognitive, and Psychosocial Outcomes in Pediatric Intestinal Failure and Transplantation
Purpose of ReviewIntestinal failure and transplantation may significantly impact physical, neurocognitive, and psychosocial development in pediatric...
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Effects of electroencephalography and regional cerebral oxygen saturation monitoring on perioperative neurocognitive disorders: a systematic review and meta-analysis
BackgroundPerioperative neurocognitive disorders (PND) is a common postoperative complication including postoperative delirium (POD), postoperative...
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Perioperative platelet count in peripheral blood is associated with the early stage of PND after major orthopedic surgery: a prospective observational study
BackgroundPerioperative neurocognitive disorders (PND) are common complications of major surgery among elderly patients, remarkably decreasing...
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Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness
Purpose of ReviewWe present a review of research on the role of melatonin in the management of sleep and circadian disorders, stressing current...
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Early postoperative neurocognitive complications in elderly patients: comparing those with and without preexisting mild cognitive impairment– a prospective study
BackgroundAs societies age, increasing numbers of older adults undergo surgeries with anesthesia. Postoperative delirium (POD) and postoperative...
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Association Between the Early Serum Lipid Metabolism Profile and Delayed Neurocognitive Recovery After Cardiopulmonary Bypass in Cardiac Surgical Patients: a Pilot Study
Cardiac surgery with extracorporeal circulation is considered to be one of the surgical types with the highest incidence of delayed neurocognitive...
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Preoperative sedentary behavior is neither a risk factor for perioperative neurocognitive disorders nor associated with an increase in peripheral inflammation, a prospective observational cohort study
BackgroundSurgical interventions result in a postoperative rise in circulating inflammatory cytokines and high molecular group box protein 1 (HMGB1)....
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Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors
BackgroundPerioperative neurocognitive disorders (PND) with a high incidence frequently occur in elderly surgical patients closely associated with...