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Evaluation of serum pepsinogen concentration for the diagnosis of type 1 abomasal ulcer in water buffalo
Type 1 abomasal ulcer (AU1) in cattle and buffaloes does not have specific or characteristic clinical signs, and there is a need to identify some...
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Pepsinogen ratio and brachial-ankle pulse wave velocity: a cross-sectional study on their interrelationship in atherosclerosis
BackgroundExisting research has established the pepsinogen ratio (PGR) as a complex biomarker, not only as an independent predictor for various...
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Smoking history and severe atrophic gastritis assessed by pepsinogen are risk factors for the prevalence of synchronous gastric cancers in patients with gastric endoscopic submucosal dissection: a multicenter prospective cohort study
BackgroundNo studies have evaluated the relationship between lifestyle and synchronous gastric cancers (SGCs) in patients with endoscopic submucosal...
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Brand interchangeability of pepsinogen tests in the real-world setting after eradication of Helicobacter pylori: a community-based study
BackgroundSerum pepsinogen (PG) is recommended as a screening test for premalignant gastric lesions. However, real-world evidence demonstrating its...
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Useful Serum Pepsinogen Levels for Detecting Ongoing Helicobacter pylori Infection in Asymptomatic Subjects: A Cross-Sectional Study Based on 13C-urea Breath Test Findings
Background /AimsThe serum pepsinogen (PG) assay is used to screen subjects at high risk for gastric cancer. Currently, there are few studies on the...
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Serum pepsinogen levels in different regions of China and its influencing factors: a multicenter cross-sectional study
BackgroundThe aim of this study is to investigate the difference of serum pepsinogen (PG) baseline levels in different regions of China and its...
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PG I and PG II show unique value in diagnosing postoperative biochemical recurrence in patients with gastric cancer after total gastrectomy
ObjectiveTo investigate the potential of group I pepsinogen (PG I) and group II pepsinogen (PG II) as diagnostic markers for recurrence in gastric...
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Non-invasive Testing in Gastric Diseases
Purpose of ReviewNon-invasive markers for gastric disease are highly useful, ideally allowing to diagnose a disease or a condition in a simple and...
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Gastric adenocarcinoma of fundic gland type with autoimmune gastritis
An 87-year-old man with dysphagia presented to our hospital. He was diagnosed with autoimmune gastritis (AIG) with severe atrophy and...
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A case of gastric adenocarcinoma with pyloric gland-type infiltrating submucosa
BackgroundThe development of immunohistochemical staining has revealed that gastric adenocarcinoma with the gastric phenotype can be divided into the...
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Randomized controlled trial comparing the costs of gastric cancer screening systems between serological risk-based upper gastrointestinal endoscopy and the existing barium photofluorography: gastric cancer screening labeled by serum examination in place of aged gastric cancer organized screening systems (GALAPAGOS study)
BackgroundAlthough the risk of gastric cancer can be stratified according to Helicobacter pylori ( H. pylori ) IgG antibody titer and pepsinogen...
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Clinical applicability of a new scoring system for population-based screening and risk factors of gastric cancer in the Wannan region
BackgroundWe aimed to evaluate the clinical applicability of a new scoring system that comprises the variables age, sex, pepsinogen ratio (PGR),...
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Diagnostic performance of the normal range of gastrin calculated using strict criteria based on a combination of serum markers and pathological evaluation for detecting gastritis: a retrospective study
BackgroundThe ABC method, which combines the pepsinogen method and anti -Helicobacter pylori antibody titers, has been used for risk screening for...
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Endoscopic evaluation by the Kyoto classification of gastritis combined with serum anti-Helicobacter pylori antibody testing reliably risk-stratifies subjects in a population-based gastric cancer screening program
BackgroundWe previously demonstrated that the Kyoto classification of gastritis was useful for judging the status of Helicobacter pylori infection...
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Evaluation of screening tests for autoimmune gastritis in histopathologically confirmed Japanese patients, and re-evaluation of histopathological classification
BackgroundThe aims of the present study are to evaluate non-invasive screening tests for autoimmune gastritis (AIG) and re-evaluate histopathological...
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Early autoimmune gastritis presenting with a normal endoscopic appearance
This report describes a patient with early-stage autoimmune gastritis (AIG) presenting with a normal endoscopic appearance. A 66-year-old man with...
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Gastric adenocarcinoma of the fundic gland type: clinicopathological features of eight patients treated with endoscopic submucosal dissection
BackgroundGastric adenocarcinoma of the fundic gland type (GA-FG) has been added to the 2019 edition of the World Health Organization’s list of...
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Randomised clinical trial: 3-year interim analysis results of the VISION trial to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive oesophagitis
BackgroundVISION is a randomised, phase 4, open-label, parallel-group, multicentre study conducted in 33 centres in Japan. The aim of this study was...
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Pyloric, pseudopyloric, and spasmolytic polypeptide-expressing metaplasias in autoimmune gastritis: a case series of 22 Japanese patients
There are two types of pyloric gland-like metaplasia in the corpus of stomach: pyloric and pseudopyloric metaplasias. They show the same morphology...
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How to Improve the Efficacy of Gastric Cancer Screening?
Purpose of reviewThis review article aims to provide an overview of existing and emerging screening strategies for gastric cancer and discuss...
