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Mature B, T and NK-cell, plasma cell and histiocytic/dendritic cell neoplasms: classification according to the World Health Organization and International Consensus Classification
In 2022, two updated classification systems for lymphoid neoplasms were published by the World Health Organization (WHO Classification of...
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Diagnostic and prognostic molecular pathology of lymphoid malignancies
With the explosion in knowledge about the molecular landscape of lymphoid malignancies and the increasing availability of high throughput techniques,...
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A genetic profiling guideline to support diagnosis and clinical management of lymphomas
The new lymphoma classifications (International Consensus Classification of Mature Lymphoid Neoplasms, and 5th World Health Organization...
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The 2022 classifications of lymphoid neoplasms
Classification of hematological neoplasms in the past 25 years has been generated through international efforts to achieve broad consensus among...
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What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?
The classification of tumors is essential in the diagnosis and clinical management of patients with malignant neoplasms. The World Health...
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Circulating Tumor DNA in Lymphoma
Purpose of ReviewRecent advances have been made in circulating tumor DNA (ctDNA), the method to minimally invasive detect lymphoma sensitively with...
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Molecular insights into pathogenesis and targeted therapy of peripheral T cell lymphoma
Peripheral T-cell lymphomas (PTCLs) are biologically and clinically heterogeneous diseases almost all of which are associated with poor outcomes....
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New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders
EBV-associated lymphoproliferative disorders (LPD) include conditions of B, T, and NK cell derivation with a wide clinicopathological spectrum...
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Biomarker-driven management strategies for peripheral T cell lymphoma
Peripheral T cell lymphomas are heterogeneous diseases which remain treatment challenges. Recent advances in molecular and genomic profiling have...
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The mutational landscape of histiocytic sarcoma associated with lymphoid malignancy
Histiocytic sarcoma and tumors with dendritic cell differentiation (HDT) are uncommon neoplasms often with an aggressive clinical course that may...
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Novel targeted therapies of T cell lymphomas
T cell lymphomas (TCL) comprise a heterogeneous group of non-Hodgkin lymphomas (NHL) that often present at an advanced stage at the time of diagnosis...
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Advances in single-cell RNA sequencing and its applications in cancer research
Cancers are a group of heterogeneous diseases characterized by the acquisition of functional capabilities during the transition from a normal to a...