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Patient-centricity in digital measure development: co-evolution of best practice and regulatory guidance
Digital health technologies (DHTs) have the potential to modernize drug development and clinical trial operations by remotely, passively, and...
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Promise of Real-World Evidence for Patient Centricity in Gulf Cooperation Council Countries: Call to Action
Presently, Gulf Cooperation Council countries are lagging in the generation of real-world data and use of real-world evidence for patient-centered...
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A Foundation for Patient-Centered Core Impact Sets: Key Learnings from Past and Existing Approaches
Despite growing commitment to patient centricity, challenges persist in consistently identifying the impacts of disease and/or treatment that...
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Patient-Centered Core Impact Sets: What They are and Why We Need Them
A quote attributed to Mark Twain states, “What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The...
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Development of a web-based patient decision aid for myopia laser correction method
BackgroundIn the context of healthcare centered on the patient, Patient Decision Aids (PtDAs) acts as an essential instrument, promoting shared...
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Development and Testing of a Chronic-Disease Patient Experience Map** Toolbox
BackgroundStakeholders increasingly expect research and care delivery to be guided by and to optimize patient experiences. However, standardized...
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Let’s talk about it: an exploration of the comparative use of three different digital platforms to gather patient-reported outcome measures
BackgroundPatient-reported outcome (PRO) measures provide valuable evidence in clinical trials; however, poor compliance with PRO measures is a...
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Definition and conceptualization of the patient-centered care pathway, a proposed integrative framework for consensus: a Concept analysis and systematic review
BackgroundConfusion exists over the definition of the care pathway concept and existing conceptual frameworks contain various inadequacies which have...
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Diagnosis and management of migraine in ten steps
Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence,...
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The road to successful people-centric research in rare diseases: the web-based case study of the Immunology and Congenital Disorders of Glycosylation questionnaire (ImmunoCDGQ)
BackgroundCongenital Disorders of Glycosylation (CDG) are a complex family of rare metabolic diseases. Robust clinical data collection faces many...
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Double lumen endobronchial tube intubation: lessons learned from anatomy
BackgroundDouble lumen endobronchial tubes (DLTs) are frequently used to employ single lung ventilation strategies during thoracic surgical...
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To what degree are orphan drugs patient-centered? A review of the current state of clinical research in rare diseases
BackgroundOver the past 30 years, the healthcare industry has increasingly turned its attention to rare diseases. Regulators have emphasized the need...
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Use of neuromuscular blockade for neck dissection and association with iatrogenic nerve injury
BackgroundCranial nerve injury is an uncommon but significant complication of neck dissection. We examined the association between the use of...
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eHealth policy framework in Low and Lower Middle-Income Countries; a PRISMA systematic review and analysis
BackgroundLow and lower middle-income countries suffer lack of healthcare providers and proper workforce education programs, a greater spread of...
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Comparison of cone beam computed tomography and plane radiographs of radial fractures as a basis for radiographical measurements
BackgroundThe purpose of this study was to determine whether radiological measurements of radial fracture position made in cone beam computed...
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Neoadjuvant chemotherapy for stage II–III breast cancer: a single-center experience
IntroductionWe conducted this study to reflect a single-center experience with the use of neoadjuvant systemic chemotherapy (NAC) for the management...
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From pixels to prognosis: Imaging biomarkers for discrimination and outcome prediction of pulmonary embolism
PurposeRecent advancements in medical imaging have transformed diagnostic assessments, offering exciting possibilities for extracting biomarker-based...
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Angiographic characteristics and treatment approach in patients undergoing intra-arterial chemotherapy for retinoblastoma
PurposeTo identify the specific clinical and angiographic variables that determine the success of intra-arterial chemotherapy (IAC) in a patient with...
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Digitale Gesundheitsanwendungen (DiGA) im Spannungsfeld von Fortschritt und Kritik
Since December 2019, digital health applications (DiGA) have been included in standard care in Germany and are therefore reimbursed by the statutory...