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A cycle-consistent adversarial network for brain PET partial volume correction without prior anatomical information
PurposePartial volume effect (PVE) is a consequence of the limited spatial resolution of PET scanners. PVE can cause the intensity values of a...
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Towards accurate partial volume correction in 99mTc oncology SPECT: perturbation for case-specific resolution estimation
BackgroundCurrently, there is no consensus on the optimal partial volume correction (PVC) algorithm for oncology imaging. Several existing PVC...
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Brain partial volume correction with point spreading function reconstruction in high-resolution digital PET: comparison with an MR-based method in FDG imaging
ObjectiveIn quantitative positron emission tomography (PET) of the brain, partial volume effect due mainly to the finite spatial resolution of the...
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DeepPVC: prediction of a partial volume-corrected map for brain positron emission tomography studies via a deep convolutional neural network
BackgroundPartial volume correction with anatomical magnetic resonance (MR) images (MR-PVC) is useful for accurately quantifying tracer uptake on...
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Characterization of point-spread function specification error on Geometric Transfer Matrix partial volume correction in [11C]PiB amyloid imaging
PurposePartial-volume correction (PVC) using the Geometric Transfer Matrix (GTM) method is used in positron emission tomography (PET) to compensate...
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Iterative framework for image registration and partial volume correction in brain positron emission tomography
Imprecise registration between positron emission tomography (PET) and anatomical magnetic resonance (MR) images is a critical source of error in MR...
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Anatomy-based correction of kidney PVE on \(^{177}\text{Lu}\) SPECT images
BackgroundIn peptide receptor radionuclide therapy (PRRT), accurate quantification of kidney activity on post-treatment SPECT images paves the way...
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Error propagation analysis of seven partial volume correction algorithms for [18F]THK-5351 brain PET imaging
BackgroundNovel partial volume correction (PVC) algorithms have been validated by assuming ideal conditions of image processing; however, in real...
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Quantification of intramyocardial blood volume using 99mTc-RBC SPECT/CT: a pilot human study
BackgroundQuantification of intramyocardial blood volume (IMBV), the fraction of myocardium that is occupied by blood, is a promising Index to...
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The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [11C]UCB-J
PurposeAging is a major societal concern due to age-related functional losses. Synapses are crucial components of neural circuits, and synaptic...
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Pitfalls in quantitative myocardial PET perfusion I: Myocardial partial volume correction
BackgroundPET quantitative myocardial perfusion requires correction for partial volume loss due to one-dimensional LV wall thickness smaller than...
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Intra- and inter-operator variability in MRI-based manual segmentation of HCC lesions and its impact on dosimetry
PurposeThe aim was to quantify inter- and intra-observer variability in manually delineated hepatocellular carcinoma (HCC) lesion contours and the...
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Position dependence of recovery coefficients in 177Lu-SPECT/CT reconstructions – phantom simulations and measurements
BackgroundAlthough the importance of quantitative SPECT has increased tremendously due to newly developed therapeutic radiopharmaceuticals, there are...
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Evaluation of 18F-flutemetamol amyloid PET image analysis parameters on the effect of verubecestat on brain amlyoid load in Alzheimer’s disease
PurposeThe BACE inhibitor verubecestat was previously found to reduce amyloid load as assessed by 18 F-flutemetamol positron emission tomography...
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An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?
BackgroundThe need for arterial blood data in quantitative PET research limits the wider usability of this imaging method in clinical research...
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The effect of calibration factors and recovery coefficients on 177Lu SPECT activity quantification accuracy: a Monte Carlo study
BackgroundDifferent gamma camera calibration factor (CF) geometries have been proposed to convert SPECT data into units of activity concentration....
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Image-derived input functions from dynamic 15O–water PET scans using penalised reconstruction
BackgroundQuantitative positron emission tomography (PET) scans of the brain typically require arterial blood sampling but this is complicated and...
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Use of intra-operative internal distraction for the application of magnetically controlled growth rods (MCGR): a technique for maximizing correction in the rigid immature spine during index surgery
ObjectiveOperative treatment of early onset scoliosis (EOS) with Magnetically Controlled Growing Rod (MCGR) in moderate-to-severe curves poses a...
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Partial-volume correction in dynamic PET-CT: effect on tumor kinetic parameter estimation and validation of simplified metrics
BackgroundPartial-volume effects generally result in an underestimation of tumor tracer uptake on PET-CT for small lesions, necessitating...
