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Paris classification of colonic polyps using CT colonography: prospective cohort study of interobserver variation
BackgroundThe Paris classification categorises colorectal polyp morphology. Interobserver agreement for Paris classification has been assessed at...
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Unsupervised identification of cardiometabolic profiles among adolescents: findings from the PARIS birth cohort study
Metabolic syndrome (MetS) is known as a risk factor in cardiometabolic morbidity but there is no consensus on its definition for teenagers. We aimed...
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Pro-active drug-facilitated crimes (DFC): a study in the Department of Forensic Medicine of Paris, France
IntroductionProactive drug facilitated crime (DFC) is the administration of psychoactive substances (PAS) for criminal purposes without the victim’s...
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Association of socioeconomic deprivation with outcomes in critically ill adult patients: an observational prospective multicenter cohort study
BackgroundThe influence of socioeconomic deprivation on health inequalities is established, but its effect on critically ill patients remains...
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In-hospital mortality of older patients with COVID-19 throughout the epidemic waves in the great Paris area: a multicenter cohort study
BackgroundMortality is high in older patients hospitalized with COVID-19. Previous studies observed lower mortality during the Omicron wave, yet no...
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Incidence of giant cell arteritis in six districts of Paris, France (2015–2017)
This prospective population-based study estimated the incidence of giant cell arteritis (GCA) in northeastern Paris. GCA cases diagnosed between 2015...
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Incidence of idiopathic nephrotic syndrome during the Covid-19 pandemic in the Paris area (France) and in the Netherlands
BackgroundThe aetiology of idiopathic nephrotic syndrome (INS) remains partially unknown. Viral infections have been associated with INS onset. Since...
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Fulvestrant and everolimus efficacy after CDK4/6 inhibitor: a prospective study with circulating tumor DNA analysis
In a prospective study (NCT02866149), we assessed the efficacy of fulvestrant and everolimus in CDK4/6i pre-treated mBC patients and circulating...
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Volumetric changes and clinical trajectories in Parkinson’s disease: a prospective multicentric study
BackgroundLongitudinal measures of structural brain changes using MRI in relation to clinical features and progression patterns in PD have been...
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Reactivation of Epstein–Barr virus among intensive care patients: a prospective observational study
PurposeHerpesvirus reactivation has been documented among patients in the intensive care unit (ICU) and is associated with increased morbidity and...
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Prognostic value of early EEG abnormalities in severe stroke patients requiring mechanical ventilation: a pre-planned analysis of the SPICE prospective multicenter study
IntroductionPrognostication of outcome in severe stroke patients necessitating invasive mechanical ventilation poses significant challenges. The...
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Effectiveness and Safety of Different Vascular Closure Devices: Multicentre Prospective Observational study
AimThe aim of this prospective, multicentre, observational study was to compare the efficacy and safety of balloon-based and non-balloon-based...
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Quality of life and depression in Wilson’s disease: a large prospective cross-sectional study
BackgroundWilson's disease (WD) is an autosomal recessive genetic disorder due to a mutation of the ATP7B gene, resulting in impaired hepatic copper...
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Infectious disease hotlines to provide advice to general practitioners: a prospective study
BackgroundTelephone hotlines in infectious diseases (ID) are part of antimicrobial stewardship programs designed to provide support and expertise in...
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Design, cohort profile and comparison of the KTD-Innov study: a prospective multidimensional biomarker validation study in kidney allograft rejection
There is an unmet need for robust and clinically validated biomarkers of kidney allograft rejection. Here we present the KTD-Innov...
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Re-ruptures and early outcomes after surgical repair of acute Achilles tendon ruptures: prospective, comparative multicenter study
PurposeThe primary objective of this study was to compare the re-rupture rate, clinical results, and functional outcomes six months after the...
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Albumin versus saline infusion for sepsis-related peripheral tissue hypoperfusion: a proof-of-concept prospective study
BackgroundAlbumin has potential endothelial protective effects through antioxidant and anti-inflammatory properties. However, the effect of albumin...
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Auto-antibodies against type I IFNs in > 10% of critically ill COVID-19 patients: a prospective multicentre study
BackgroundAuto-antibodies (auto-Abs) neutralizing type I interferons (IFN) have been found in about 15% of critical cases COVID-19 pneumonia and less...
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Study protocol of OmegaROP-2 prospective study: expression of placental fatty acid receptors in preterm newborns with retinopathy of prematurity
BackgroundIncomplete vascularization of the retina in preterm infants carries a risk of retinopathy of prematurity (ROP). Progress in neonatal...
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Prospective study of functional outcomes and return to sports after anterior cruciate ligament reconstruction in the knee
PurposeIndividual factors of low rates of return to sport after anterior cruciate ligament (ACL) reconstruction were unclear. We evaluated the impact...
