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Association of urinary chlorpyrifos, paraquat, and cyproconazole levels with the severity of fatty liver based on MRI
BackgroundThe objective of this study was to detect the urinary levels of chlorpyrifos, paraquat, and cyproconazole in residents living in Fuyang...
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Surveillance of pesticide poisoning in an East and a West Malaysian hospital: characteristics of pesticide poisoning and the early impact of a national Paraquat ban
BackgroundPrevious studies have shown that pesticide bans were associated with reduced fatal pesticide self-poisoning cases in high, and...
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Pathophysiological Changes in Rhesus Monkeys with Paraquat-Induced Pulmonary Fibrosis
PurposePulmonary fibrosis is a life-threatening lung disorder. A comprehensive understanding of the pathophysiological changes in the development of...
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Early diagnosis and staging of paraquat-induced pulmonary fibrosis using [18F]F-FAPI-42 PET/CT imaging
BackgroundParaquat (PQ) -induced pulmonary fibrosis poses a significant medical challenge due to limited treatment options and high mortality rates....
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Assessment of pulmonary fibrosis induced by paraquat using Al18F-NODA-FAPI-04 PET/CT
The lack of a highly sensitive method to evaluate paraquat (PQ)-induced pulmonary fibrosis and predict disease progression remains an unresolved...
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Development and validation of a sensitive and high throughput UPLC–MS/MS method for determination of paraquat and diquat in human plasma and urine: application to poisoning cases at emergency departments of hospitals
PurposeParaquat and diquat are well-known toxic herbicides, at least responsible for hundreds of fatal poisoning events worldwide. However, the...
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Use of low-molecular-weight heparin in severe paraquat poisoning: a case report
BackgroundAcute paraquat ingestion remains a leading cause of mortality in develo** countries. There is currently no evidence that treatment with...
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Aqueous Thunbergia laurifolia leaf extract alleviates paraquat-induced lung injury in rats by inhibiting oxidative stress and inflammation
BackgroundParaquat (PQ) has been reported to have a high mortality rate. The major target organ of PQ poisoning is the lungs. The pathogenesis of...
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Neuroprotective effects of pomegranate (Punica granatum L.) juice and seed extract in paraquat-induced mouse model of Parkinson’s disease
BackgroundParaquat, (PQ), an herbicide that can induce Parkinsonian-like symptoms in rodents and humans. The consumption of phytochemical-rich plants...
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Mortality from Parkinson’s disease and other causes among a workforce manufacturing paraquat: an updated retrospective cohort study
BackgroundEpidemiological studies of the association between Parkinson’s disease (PD) and paraquat (PQ) exposure have given inconsistent findings....
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Effects of pirfenidone, vitamin E, and pirfenidone–vitamin E combination in paraquat-induced pulmonary fibrosis
Paraquat-induced pulmonary fibrosis is a progressive and fatal interstitial lung disease, a condition for that, there is no effective treatment and...
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Social and economic variables related with Paraquat self-poisoning: an ecological study
BackgroundParaquat self-poisonings constitute a significant contributor to the global burden of suicide. Our aim was to evaluate the relationship...
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Combined signaling of NF-kappaB and IL-17 contributes to Mesenchymal stem cells-mediated protection for Paraquat-induced acute lung injury
BackgroundParaquat (PQ) is an herbicide widely used in the world . PQ can cause pulmonary toxicity and even acute lung injury. Treatment for PQ...
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Simultaneous determination of water-soluble herbicides using hydrophilic interaction liquid chromatography–mass spectrometry
PurposeThe analysis of water-soluble herbicides, including glyphosate (Glyp), glufosinate (Gluf), paraquat (PQ), and diquat (DQ), is time-consuming...
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YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells
Paraquat (PQ) is a widely used herbicide and a common cause of poisoning that leads to pulmonary fibrosis with a high mortality rate. However, the...
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The investigation of the role of sirtuin-1 on embryo implantation in oxidative stress–induced mice
PurposeImplantation is essential for a successful pregnancy. Despite the increasing number of studies, implantation is still an unknown process. This...
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Ingestion poisoning related lung injury- a pictorial review
Poison ingestion is a medical emergency requiring immediate care in the emergency department. Respiratory symptoms with ingested poisons can occur...
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Neuroprotective compounds from marine invertebrates
BackgroundNeuroinflammation is a key pathological feature of a wide variety of neurological disorders, including Parkinson’s, multiple sclerosis,...
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Metabolitic profiling of amino acids in paraquat-induced acute kidney injury
BackgroundThe herbicide paraquat (1, 1′-dimethyl-4, 4′-bipyridylium dichloride; PQ) is a poison well-known to cause delayed mortality due to acute...