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Etanercept-associated episcleritis: a pediatric case report of a paradoxical adverse reaction and review of the literature
Scleritis is an inflammation of the episcleral and scleral tissues, characterized by injection in both superficial and deep episcleral vessels. When...
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Post-tuberculosis treatment paradoxical reactions
Paradoxical reactions (PR) to tuberculosis (TB) treatment are common during treatment, but have also been described after treatment. A presentation...
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Paradoxical psoriasis induced by IL-17 inhibitors: a case series of patients with axial spondyloarthritis and a systematic literature review
Following the market authorization of interleukin (IL)-17 inhibitors, a growing number of cases of IL-17 inhibitor-induced paradoxical psoriasis...
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Some Drugs Have Two Faces: Paradoxical Colitis in a Patient with Psoriatic Arthritis Previously Treated with Etanercept and IL-17 Inhibitors
Tumor necrosis factor-alpha (TNF-α) and interleukin-17 (IL-17) inhibitors are among the most potent treatments for inflammatory arthropathies...
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A case of paradoxical response during anti-tuberculosis treatment in a patient with ulcerative colitis
Emerging anti-tumor necrosis factor (TNF)-α antibodies therapy changed treatment strategy to inflammatory bowel diseases because of the efficacy....
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Pelvic and central nervous system tuberculosis complicated by a paradoxical response manifesting as a spinal tuberculoma: a case report
BackgroundThe post-partum period is a risk factor for tuberculosis (TB), possibly including the period after miscarriage as illustrated here. This...
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Adalimumab Biosimilar-Induced Severe Paradoxical Palmoplantar Pustulosis in a Patient with Psoriasis and Psoriatic Arthritis Successfully Treated with Ixekizumab
Psoriasis vulgaris is a chronic immune-mediated inflammatory disease of the skin. Biologic therapy has been available for more than 10 years and has...
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Paradoxical sleep deprivation induces tissue changes in the parotid gland of rats
PurposeThis study aimed to evaluate if paradoxical sleep deprivation induces some tissue changes in the parotid gland of rats.
Methods ...
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Paradoxical manifestations during tuberculous meningitis treatment among HIV-negative patients: a retrospective descriptive study and literature review
BackgroundTuberculous meningitis (TBM) is the most frequent, severe, and disabling form of central nervous system (CNS) tuberculosis (TB). TBM...
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Pseudomyopia with paradoxical accommodation: a case report
BackgroundPseudomyopia is caused by increased refractive power by ciliary muscle spasm. Most patients cannot overcome pseudomyopia spontaneously;...
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Paradoxical effect of anti-inflammatory drugs on IL-6 mRNA expression in patients with PTSD during treatment
The pathophysiology of posttraumatic stress disorder (PTSD) is associated with the activation of the innate immune system, including cytokines like...
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Corticosteroid therapy for the management of paradoxical inflammatory reaction in patients with pulmonary tuberculosis
BackgroundParadoxical reaction after the initiation of tuberculosis treatment is defined as increased inflammation following effective...
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Paradoxical Skin Reaction to Certolizumab, an Overlap of Pyoderma Gangrenosum and Psoriasis in a Young Woman Treated for Ankylosing Spondylitis: Case Report with Literature Review
IntroductionBiologic agents form an indispensable part of modern therapeutic regimens for the treatment of severe inflammatory diseases, especially...
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Paradoxical increase in left atrial strains early after Covid-19 infection, a result of comprehensive recovery phase four-chamber strains study
Cardiac consequences of Covid-19 infection have been mentioned in various studies as a serious risk factor for in-hospital mortality. However, the...
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Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks
Impulse control disorders (ICDs), a wide spectrum of maladaptive behaviors which includes pathological gambling, hypersexuality and compulsive...
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Complicated Surgical Site Infection with Mycobacterium Abscessus After Liposuction and Affections of Corticosteroids in the Treatment Regimen: Three Cases Report and a Systematic Review
IntroductionMycobacterium abscessus infection after liposuction/fat grafting is a rare complication that is hard to diagnose and treat. Misdiagnosis...
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Psoriasis as an adverse reaction to biologic agents beyond anti-TNF-α therapy
New onset or exacerbation of pre-existing psoriasis after therapeutic TNF-α inhibition is a well-described phenomenon. Over the last two decades,...