Search
Search Results
-
Correlation between ovarian follicular development and Hippo pathway in polycystic ovary syndrome
BackgroundFor women of childbearing age, the biggest problem caused by polycystic ovary syndrome (PCOS) is infertility, which is mainly caused by...
-
Zinc deficiency deteriorates ovarian follicle development and function by inhibiting mitochondrial function
Zinc (Zn) is a crucial trace element essential for human growth and development, particularly for reproductive health. Previous research has shown a...
-
MicroRNA-338-3p helps regulate ovarian function by affecting granulosa cell function and early follicular development
BackgroundFollicular development in mammalian ovaries is a complex and dynamic process, and the interactions and regulatory-feedback loop between the...
-
BDNF promotes mouse follicular development and reverses ovarian aging by promoting cell proliferation
BackgroundBrain-derived neurotrophic factor (BDNF) plays an important role in ovarian function including follicle development and oocyte maturation,...
-
SRC-3/TRAF4 facilitates ovarian cancer development by activating the PI3K/AKT signaling pathway
ObjectiveOvarian cancer is the seventh most common cancer in women, and it causes many deaths in women worldwide. Patients with ovarian cancer have a...
-
PIM2 Promotes the Development of Ovarian Endometriosis by Enhancing Glycolysis and Fibrosis
Endometriosis is a common gynecological disorder characterized by the presence of the endometrial glands and the stroma outside the uterine cavity....
-
Revisiting macrophages in ovarian cancer microenvironment: development, function and interaction
Tumor-associated macrophages (TAMs) are an important component of the tumor microenvironment (TME) and have been linked to immunosuppression and poor...
-
Development and clinical validation of a seven-gene signature based on tumor stem cell-related genes to predict ovarian cancer prognosis
ObjectiveTumors are highly heterogeneous, and within their parenchyma, a small population of tumor-stem cells possessing differentiation potential,...
-
DNA methylation profiles of ovarian cysts resemble ovarian tissues but not endometrial tissues
IntroductionEndometriosis is a heritable, complex chronic inflammatory disease, for which much of the causal pathogenic mechanism remain...
-
Managing Coexistent Triad of Ovarian Tumors while Conserving Ovarian Function
The coexistence of three histologically distinct ovarian tumors is exceedingly rare, posing challenges for accurate diagnosis and management. This...
-
Conservative Hypomethylation of Mesenchymal Stem Cells and Their Secretome Restored the Follicular Development in Cisplatin-Induced Premature Ovarian Failure Mice
Premature ovarian failure (POF) is one of the main causes of infertility in women under the age of 40 years. Recently , epigenetic reprogramming,...
-
Transcription factor c-fos induces the development of premature ovarian insufficiency by regulating MALAT1/miR-22-3p/STAT1 network
BackgroundThe current study attempted to investigate the role of transcription factor c-fos in the development of premature ovarian insufficiency...
-
The Reproductive Lifespan of Ovarian Follicle
The functional unit within mammalian ovaries is the ovarian follicle. The development of the ovarian follicle is a lengthy process beginning from the...
-
Toxic effect window of ovarian development in female offspring mice induced by prenatal prednisone exposure with different doses and time
BackgroundPrednisone is one of the most used synthetic glucocorticoids during pregnancy. Epidemiological investigations suggested that prenatal...
-
Ovarian tissue cryopreservation for fertility preservation before hematopoietic stem cell transplantation in patients with sickle cell disease: safety, ovarian function follow-up, and results of ovarian tissue transplantation
PurposeTo describe the experience of performing ovarian tissue cryopreservation (OTC) before hematopoietic stem cell transplantation (HSCT), among...
-
An immune related signature inhibits the occurrence and development of serous ovarian cancer by affecting the abundance of dendritic cells
Serous ovarian cancer is one of the major causes of cancer related death among women worldwide. The advanced diagnosis worsens the prognosis of...
-
Mitochondrial Quality Control in Ovarian Function: From Mechanisms to Therapeutic Strategies
Mitochondrial quality control plays a critical role in cytogenetic development by regulating various cell-death pathways and modulating the release...
-
Heterogeneity and treatment landscape of ovarian carcinoma
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and anatomical levels, both spatially and temporally. This...
-
LncRNA GAS5-hnRNPK axis inhibited ovarian cancer progression via inhibition of AKT signaling in ovarian cancer cells
BackgroundThe incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first.
MethodsThe expression of...
-
Long-term effect of chemotherapy after ovarian decortication on the ovarian function in women surviving cancer
PurposeOvarian decortication may affect ovarian function. We investigated the status of ovarian reserve after ovarian decortication plus chemotherapy...
