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Early Osteoarthritis State-of-the-Art Approaches to Diagnosis, Treatment and Controversies
Early osteoarthritis is novel topic for orthopedic surgeons and its process begins immediately after joint injury. The mechanical restoration of the...
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Contralateral knee osteoarthritis is a risk factor for ipsilateral knee osteoarthritis progressing: a case control study
BackgroundKnee osteoarthritis (KOA) is a highly disabling disease, and studying its progression is crucial. However, it is still unclear whether the...
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Cross-cultural adaptation and psychometric testing of the Yoruba lequesne algofunctional index of knee osteoarthritis among patients with knee osteoarthritis
BackgroundThe Lequesne Algofunctional Index of Knee Osteoarthritis (LAIKOA) is a widely used knee osteoarthritis (KOA) outcome measure and is...
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Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment?
Purpose of reviewPatient-centred care for people with osteoarthritis requires shared decision making. Understanding and considering patients’...
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Defining hip osteoarthritis feature prevalence, severity, and change using the Scoring of Hip Osteoarthritis with MRI (SHOMRI)
ObjectiveTo define the reporting of Scoring Hip Osteoarthritis with MRI (SHOMRI) feature prevalence and severity, and to develop criteria to monitor...
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Osteoarthritis as an Enhanceropathy: Gene Regulation in Complex Musculoskeletal Disease
Purpose of ReviewOsteoarthritis is a complex and highly polygenic disease. Over 100 reported osteoarthritis risk variants fall in non-coding regions...
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Regional disparities, age-related changes and sex-related differences in knee osteoarthritis
BackgroundThe objective of the study is to analyse the regions, age and sex differences in the incidence of knee osteoarthritis (KOA).
...
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Phenotypes of osteoarthritis-related knee pain and their transition over time: data from the osteoarthritis initiative
BackgroundIdentification of knee osteoarthritis (OA) pain phenotypes, their transition patterns, and risk factors for worse phenotypes, may guide...
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Molecular biomarker approaches to prevention of post-traumatic osteoarthritis
Up to 50% of individuals develop post-traumatic osteoarthritis (PTOA) within 10 years following knee-joint injuries such as anterior cruciate...
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The ligamentum mucosum’s potential as a preventative structure in the development of knee osteoarthritis
PurposeThis paper aimed to identify whether the presence, type, and/or morphology of the ligamentum mucosum could play a role in the development of...
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Clinical phenotypes of comorbidities in end-stage knee osteoarthritis: a cluster analysis
ObjectivesComorbidities, as components of these heterogeneous features, often coexist with knee osteoarthritis, and are particularly prevalent in...
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Gardening/yardwork in people with knee osteoarthritis is not associated with symptom or structural progression over 48 months: data from the Osteoarthritis Initiative
ObjectiveTo evaluate the relationship of gardening/yardwork with symptomatic and structural progression in those with pre-existing radiographic knee...
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Burden of osteoarthritis in China, 1990–2019: findings from the Global Burden of Disease Study 2019
This study aimed to report the most current data on the incidence and disability-adjusted life years (DALY) associated with osteoarthritis in China...
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Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis
Osteoarthritis (OA) is a common degenerative disease worldwide and new therapeutics that target inflammation and the crosstalk between immunocytes...
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Balneotherapy for osteoarthritis: a systematic review
This systematic review is aimed to evaluate the effects of balneotherapy with thermal mineral water for managing the symptoms and signs of...
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Association between Elevated Magnesium Intake and Reduced Risk of Recurrent Falls and Frailty in Osteoarthritis: Data from the Osteoarthritis Initiative
ObjectivesThe objective of this 8-year follow-up study was to investigate the relationship between magnesium intake and frailty, as well as recurrent...
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Knee arthroscopy has limited effects on relieving local symptoms of knee osteoarthritis: an analysis of data from the Osteoarthritis Initiative
BackgroundKnee arthroscopy’s efficacy in symptom improvement for knee osteoarthritis remains debated. In this study, we analyzed a multicenter...
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Innovation in Targeted Intra-articular Therapies for Osteoarthritis
Osteoarthritis is the most common chronic joint disease characterized by progressive damage to the joints, leading to pain and loss of function....
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Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses
Background and ObjectiveAlthough paracetamol (acetaminophen) combined with other analgesics can reduce pain intensity in some pain conditions, its...
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Genetically predicted obesity and risk of hip osteoarthritis
ObjectivesTo determine the causal association between genetically predicted obesity and the risk of hip osteoarthritis.
MethodsWe performed...
