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  1. Oral Papillary Squamous Cell Carcinoma and Oral Squamous Cell Carcinoma: A Histopathological and Immunohistochemical Comparative Study

    Purpose

    The aim of the study is to investigate the immunohistochemical expression of both Alpha smooth muscle actin and Transforming Growth Factor...

    Esraa Ashraf Mahmoud, Mohsen Kazem Abdellatif, Sarah Ahmed Mohammed Mahmoud in Head and Neck Pathology
    Article Open access 17 June 2024
  2. Enigma of Acantholytic and Clear Cell Changes in Oral Squamous Cell Carcinoma

    Only limited cases have been reported about the clear cell variant of squamous cell carcinoma occurring in the oral cavity. The present study regards...

    Ayushi Jain, Sharon John, Shalini Gupta in Head and Neck Pathology
    Article 15 March 2024
  3. Role of Hematological Markers in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma

    Various haematological markers have been shown to be diagnostic and prognostic in oral cancer. This study compares the values of the inflammatory...

    Bhargav Ram, Mahabaleshwara Chalathadka, ... **eshwar Patil Adagouda in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 26 April 2023
  4. High incidence of HPV infection in minors with oral squamous cell carcinoma

    Background

    Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human...

    Ningxiang Wu, Yonghui Li, ... Ran Zhang in Diagnostic Pathology
    Article Open access 09 March 2024
  5. Application of Natural Medicinal Plants Active Ingredients in Oral Squamous Cell Carcinoma

    Oral squamous cell carcinoma (OSCC) is the most common malignant cancer of the head and neck, with high morbidity and mortality, ranking as the sixth...

    Qun-li Ren, **ao-lan Li, ... Jian-guo Liu in Chinese Journal of Integrative Medicine
    Article 12 April 2024
  6. Oral Carcinoma Cuniculatum: A Variant of Squamous cell Carcinoma with Unique Histological Characteristics and a Diagnostic Challenge

    Oral carcinoma cuniculatum (OCC) is a rare squamous cell carcinoma (SCC) variant with low incidence often due to misdiagnosis. This report aims to...

    Venakata Joga Prasanth Mokhasanavisu, Mohamed Taher Mithi, ... Shashank J Pandya in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 06 May 2023
  7. Prognostic Effectiveness of PD-L1 Tumoral Expression in Oral Cavity Squamous Cell Carcinoma

    PD-L1 is a glycoprotein present on antigen-presenting cells and malignant cells and activates the PD-L1 receptor on cells surfaces, leading to T-cell...

    Ambesh Singh, Nitin M. Nagarkar, ... Prajwal S. Dange in Indian Journal of Surgical Oncology
    Article 26 June 2024
  8. Oral Metronomic Chemotherapy in Advanced and Metastatic Oral Squamous Cell Carcinoma: A Need of the Hour

    Aim

    The present review article aims to compile the best available evidence-based data on oral metronomic chemotherapy (OMCT) including its mechanism...

    Naveena A. N. Kumar, Punit Singh Dikhit, ... Mahadev Rao in Journal of Maxillofacial and Oral Surgery
    Article Open access 04 July 2023
  9. Evaluation of Safe Margins Using Immunohistochemistry in Oral Squamous Cell Carcinoma

    Background

    Hematoxylin & Eosin (H & E) stains have been conventionally used to establish the status of safe margins following resection of primary...

    Aaisha Siddiqa, Divya Jivrajani, ... Sadanand Shivanna Kuntaraddi in Journal of Maxillofacial and Oral Surgery
    Article 25 June 2024
  10. Histomorphological Evidence of Complex Cannibalism—An Uncharted Territory in Oral Squamous Cell Carcinoma

    Complex cannibalism (CxC) is an emerging new seeming entity in oral squamous cell carcinoma (OSCC) embody as a prime metabolic event in determining...

    R Keerthika, Anju Devi, ... Gitika Sharma in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 19 January 2024
  11. Neoadjuvant Immunotherapy for Head and Neck Squamous Cell Carcinoma: Expecting Its Application in Temporal Bone Squamous Cell Carcinoma

    Temporal bone malignant tumors are characterized by atypical clinical symptoms, and easy recurrence and metastasis. They account for 0.2% of head and...

    Meng-wen Shi, **g Huang, Yu Sun in Current Medical Science
    Article 26 March 2023
  12. Rectus Abdominis Muscle Metastasis of Oral Tongue Squamous Cell Carcinoma:A Rare Clinical Entity

    Distant metastasis of oral squamous cell carcinoma to skeletal muscles is an extremely rare entity and is an indicator of poor prognosis for the...

    Mansi Dey, Khushnud Alam, ... Cheena Garg in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 16 March 2024
  13. POLE2 Regulates Apoptosis of Oral Squamous Cell Carcinoma Cells through the PI3K/AKT Signaling Pathway

    Objective

    Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the head and neck, but its occurrence and progression mechanisms...

    Ming-yu Sun, Lin Wang, Zheng-yu Shen in Current Medical Science
    Article 11 December 2023
  14. Role of tissue markers associated with tumor microenvironment in the progression and immune suppression of oral squamous cell carcinoma

    Head and neck cancers (HNC) continues to dominate major cancers contributing to  mortality worldwide. Squamous cell carcinoma is the major type of...

    Suganya Ramalingam, Sivaramakrishnan Shantha, ... Venkatachalam Deepa Parvathi in Medical Oncology
    Article 20 September 2023
  15. Perineural invasion in incisional biopsy is an indication for in-continuity resection in oral squamous cell carcinoma of the tongue and floor of the mouth

    Purpose

    The histologic finding of perineural invasion is a poor prognostic factor in oral squamous cell carcinoma patients. The aim of this study is...

    George Kostakis, Panagiotis Papadopoulos, Panagiotis Stathopoulos in Oral and Maxillofacial Surgery
    Article 04 January 2024
  16. Vitamin D-metabolizing enzyme CYP24A1 affects oncogenic behaviors of oral squamous cell carcinoma and its prognostic implication

    Vitamin D is an essential molecule for cellular homeostasis, playing a critical role in cell fate decisions including cell proliferation,...

    Yuna Nakamori, Akira Takasawa, ... Makoto Osanai in Medical Molecular Morphology
    Article 21 May 2024
  17. Clear cell Odontogenic Carcinoma Mandible Mimicking oral Cavity Squamous cell Carcinoma: An Intriguing case with Review of Literature

    Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic neoplasm with high risk of recurrence and aggressive behaviour. Presence of clear cells...

    Ashok Kumar Das, Kirti Khandelwal in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 16 December 2022
  18. Expression of Minichromosome Maintenance Protein 2 (MCM2) in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Systematic Review

    The histopathological investigations of oral lesions are a basic approach for diagnosing ongoing cancer or pre-cancer associated pathological...

    Manisha S. Ahire, Saurabh R. Nagar, ... Shubhangi M. Dalvi in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 29 December 2022
  19. Evaluation of Diagnostic Significance of Salivary miRNA-184 and miRNA-21 in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders

    Background

    Altered levels of miRNAs might affect the pathogenesis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders...

    Aarushi Garg, Aadithya B. Urs, ... Sameer Ahmad Guru in Head and Neck Pathology
    Article 28 November 2023
  20. Over Expression of Cancer Stem Cell Marker CD44 and Its Clinical Significance in Patients with Oral Squamous Cell Carcinoma

    Cancer stem cell marker CD44 is a cell-surface glycoprotein which is involved in various cellular functions such as cell–cell interactions, cell...

    Baldeep Singh, Sadhna Aggarwal, ... Satya N. Das in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 06 October 2022
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