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Oral Papillary Squamous Cell Carcinoma and Oral Squamous Cell Carcinoma: A Histopathological and Immunohistochemical Comparative Study
PurposeThe aim of the study is to investigate the immunohistochemical expression of both Alpha smooth muscle actin and Transforming Growth Factor...
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Enigma of Acantholytic and Clear Cell Changes in Oral Squamous Cell Carcinoma
Only limited cases have been reported about the clear cell variant of squamous cell carcinoma occurring in the oral cavity. The present study regards...
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Role of Hematological Markers in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma
Various haematological markers have been shown to be diagnostic and prognostic in oral cancer. This study compares the values of the inflammatory...
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High incidence of HPV infection in minors with oral squamous cell carcinoma
BackgroundOral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human...
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Application of Natural Medicinal Plants Active Ingredients in Oral Squamous Cell Carcinoma
Oral squamous cell carcinoma (OSCC) is the most common malignant cancer of the head and neck, with high morbidity and mortality, ranking as the sixth...
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Oral Carcinoma Cuniculatum: A Variant of Squamous cell Carcinoma with Unique Histological Characteristics and a Diagnostic Challenge
Oral carcinoma cuniculatum (OCC) is a rare squamous cell carcinoma (SCC) variant with low incidence often due to misdiagnosis. This report aims to...
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Prognostic Effectiveness of PD-L1 Tumoral Expression in Oral Cavity Squamous Cell Carcinoma
PD-L1 is a glycoprotein present on antigen-presenting cells and malignant cells and activates the PD-L1 receptor on cells surfaces, leading to T-cell...
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Oral Metronomic Chemotherapy in Advanced and Metastatic Oral Squamous Cell Carcinoma: A Need of the Hour
AimThe present review article aims to compile the best available evidence-based data on oral metronomic chemotherapy (OMCT) including its mechanism...
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Evaluation of Safe Margins Using Immunohistochemistry in Oral Squamous Cell Carcinoma
BackgroundHematoxylin & Eosin (H & E) stains have been conventionally used to establish the status of safe margins following resection of primary...
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Histomorphological Evidence of Complex Cannibalism—An Uncharted Territory in Oral Squamous Cell Carcinoma
Complex cannibalism (CxC) is an emerging new seeming entity in oral squamous cell carcinoma (OSCC) embody as a prime metabolic event in determining...
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Neoadjuvant Immunotherapy for Head and Neck Squamous Cell Carcinoma: Expecting Its Application in Temporal Bone Squamous Cell Carcinoma
Temporal bone malignant tumors are characterized by atypical clinical symptoms, and easy recurrence and metastasis. They account for 0.2% of head and...
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Rectus Abdominis Muscle Metastasis of Oral Tongue Squamous Cell Carcinoma:A Rare Clinical Entity
Distant metastasis of oral squamous cell carcinoma to skeletal muscles is an extremely rare entity and is an indicator of poor prognosis for the...
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POLE2 Regulates Apoptosis of Oral Squamous Cell Carcinoma Cells through the PI3K/AKT Signaling Pathway
ObjectiveOral squamous cell carcinoma (OSCC) is the most common malignant tumor of the head and neck, but its occurrence and progression mechanisms...
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Role of tissue markers associated with tumor microenvironment in the progression and immune suppression of oral squamous cell carcinoma
Head and neck cancers (HNC) continues to dominate major cancers contributing to mortality worldwide. Squamous cell carcinoma is the major type of...
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Perineural invasion in incisional biopsy is an indication for in-continuity resection in oral squamous cell carcinoma of the tongue and floor of the mouth
PurposeThe histologic finding of perineural invasion is a poor prognostic factor in oral squamous cell carcinoma patients. The aim of this study is...
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Vitamin D-metabolizing enzyme CYP24A1 affects oncogenic behaviors of oral squamous cell carcinoma and its prognostic implication
Vitamin D is an essential molecule for cellular homeostasis, playing a critical role in cell fate decisions including cell proliferation,...
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Clear cell Odontogenic Carcinoma Mandible Mimicking oral Cavity Squamous cell Carcinoma: An Intriguing case with Review of Literature
Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic neoplasm with high risk of recurrence and aggressive behaviour. Presence of clear cells...
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Expression of Minichromosome Maintenance Protein 2 (MCM2) in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Systematic Review
The histopathological investigations of oral lesions are a basic approach for diagnosing ongoing cancer or pre-cancer associated pathological...
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Evaluation of Diagnostic Significance of Salivary miRNA-184 and miRNA-21 in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders
BackgroundAltered levels of miRNAs might affect the pathogenesis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders...
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Over Expression of Cancer Stem Cell Marker CD44 and Its Clinical Significance in Patients with Oral Squamous Cell Carcinoma
Cancer stem cell marker CD44 is a cell-surface glycoprotein which is involved in various cellular functions such as cell–cell interactions, cell...