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Understanding the functional relevance of oral neutrophils, phenotype and properties in OSCC
Neutrophils are the predominant white blood cells (WBC) that are recruited to the sites of inflammation and infection. They are acknowledged to...
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Deregulation of cytokine affecting oral neutrophil subsets in oral cancer
The most prevalent form of leukocytes in human blood, neutrophils, is regarded as an essential part of the innate immune system and the body’s 1st...
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Neutrophils in Inflammatory Bone Diseases
Purpose of ReviewIn this review, we summarize the current evidence that suggests that neutrophils play a key role in facilitating damage to local...
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Neutrophils in cancer: dual roles through intercellular interactions
Neutrophils, the most abundant immune cells in human blood, play crucial and diverse roles in tumor development. In the tumor microenvironment (TME),...
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Semaglutide modulates prothrombotic and atherosclerotic mechanisms, associated with epicardial fat, neutrophils and endothelial cells network
BackgroundObesity has increased in recent years with consequences on diabetes and other comorbidities. Thus, 1 out of 3 diabetic patients suffers...
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Interplay between tumor-derived factors and tumor-associated neutrophils: opportunities for therapeutic interventions in cancer
Neutrophils have emerged as important players in the tumor microenvironment, largely attributed to their plasticity and heterogeneity. Evidence...
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The Mechanism of IL-17 Regulating Neutrophils Participating in Host Immunity of RVVC Mice
Vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) are the most common lower genital tract infections in reproductive...
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Cytokines secreted by inflamed oral mucosa: implications for oral cancer progression
The oral mucosa has an essential role in protecting against physical, microbial, and chemical harm. Compromise of this barrier triggers a wound...
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Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis
BackgroundPrimary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for...
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Neutrophils as potential therapeutic targets in hepatocellular carcinoma
The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic therapies for hepatocellular carcinoma (HCC) towards...
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Role of Hematological Markers in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma
Various haematological markers have been shown to be diagnostic and prognostic in oral cancer. This study compares the values of the inflammatory...
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Bronchial eosinophils, neutrophils, and CD8 + T cells influence asthma control and lung function in schoolchildren and adolescents with severe treatment-resistant asthma
BackgroundStudies in adult severe treatment-resistant asthma (STRA) have demonstrated heterogeneous pathophysiology. Studies in the pediatric age...
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Oral Psoriasis—An Overlooked Entity: Current Paradigms and Future Perspectives
Purpose of ReviewPsoriasis is a chronic, genetically determined, scaly, and inflammatory disease of the skin. Pathogenesis is multi-factorial,...
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The Oral-Vascular-Pulmonary Infection Route: a Pathogenic Mechanism Linking Oral Health Status to Acute and Post-Acute COVID-19
Purpose of ReviewIn recent years, much attention has focused on the role of poor oral health in the development or worsening of systemic diseases,...
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Relationship of NLRP3 Inflammasome with Oral Health
Purpose of ReviewThe aim of this review is whether the NLRP3 inflammasome is associated with oral health and to understand whether the biology of the...
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Oral Consequences of Systemic Lupus Erythematosus: an Update
Purpose of ReviewSystemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organs that has been associated with various oral...
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Neutrophils and polymorphonuclear myeloid-derived suppressor cells: an emerging battleground in cancer therapy
Neutrophils are central mediators of innate and adaptive immunity and first responders to tissue damage. Although vital to our health, their...
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Preoperative combination score of neutrophils, monocytes, and lymphocytes as a predictor for locally advanced rectal cancer
ObjectiveThe aim of this study was to investigate the prognostic value of baseline peripheral blood neutrophils, monocytes, and lymphocytes on...
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Immunophenotypic and Gene Expression Analyses of the Inflammatory Microenvironment in High-Grade Oral Epithelial Dysplasia and Oral Lichen Planus
BackgroundOral lichen planus (OLP) and oral epithelial dysplasia (OED) present diagnostic challenges due to clinical and histologic overlap. This...
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Evaluation of the topical gel and oral administration of Punica Granatum Var Pleniflora on oral mucositis induced by 5-Fluorouracil in golden hamsters
BackgroundOral mucositis (OM), an acute inflammation of the oral cavity, is a common complication in patients undergoing invasive myeloblastic...
