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Effect of direct oral anticoagulants on bleeding during and after cataract surgery
PurposeTo assess the risk for intraoperative and postoperative ocular bleeding associated with direct oral anticoagulant treatment in patients...
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Direct Oral Anticoagulants for Cancer-Associated Venous Thromboembolism
Purpose of ReviewTo present the randomized controlled trial (RCT) evidence and highlight the areas of uncertainty regarding direct oral...
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Levetiracetam Interaction with Direct Oral Anticoagulants: A Pharmacovigilance Study
BackgroundLevetiracetam is widely used in post-stroke epilepsy. However, it is suspected to possess P-glycoprotein (P-gp) induction properties, and...
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European expert consensus recommendations on the primary care use of direct oral anticoagulants in patients with venous thromboembolism
BackgroundDirect oral anticoagulants for the treatment of venous thromboembolism are supported by robust clinical trial evidence. Despite published...
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Incidence of intracranial bleeding in mild traumatic brain injury patients taking oral anticoagulants: a systematic review and meta-analysis
BackgroundTraumatic brain injury (TBI) is one of the leading causes of disability and death worldwide. Most TBI cases occur in older people, because...
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Efficacy and Safety of Direct Oral Anticoagulants in Pediatric Venous Thromboembolism: A Systematic Review and Meta-Analysis
ObjectivesTo assess the efficacy and safety of direct oral anticoagulants (DOACs) in comparison to standard-of-care (SOC) anticoagulants in the...
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Direct Oral Anticoagulants: An Update on Monitoring and Antidotes for the Perioperative Physician
Purpose of ReviewThe purpose of this review is to update the clinician on assessing and reversing the effects of direct oral anticoagulants (DOACs)...
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The methods for removal of direct oral anticoagulants and heparins to improve the monitoring of hemostasis: a narrative literature review
The assessment of hemostasis is necessary to make suitable decisions on the management of patients with thrombotic disorders. In some clinical...
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PrevAleNce and Associated factors of inappropriaTe dosing of direct Oral anticoaguLants In pAtients with Atrial Fibrillation: the ANATOLIA-AF Study
PurposeInappropriate dosing of direct oral anticoagulants is associated with an increased risk of stroke, systemic embolism, major bleeding,...
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Direct oral anticoagulants versus standard anticoagulation in children treated for acute venous thromboembolism
AbstractDirect oral anticoagulants (DOACs) are widely used to treat venous thromboembolism (VTE) in adults. Little attention is given to pediatric...
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When and How to Use Reversal Agents for Direct Oral Anticoagulants?
Purpose of ReviewOur objective is to describe currently available reversal agents for direct oral anticoagulants (DOACs), their target population,...
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An update on applications and limitations of direct oral anticoagulants
A major advancement in the field of medicine has been the introduction and usage of direct oral anticoagulants (DOACs) such as dabigatran (Pradaxa),...
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Direct oral anticoagulants: patient reported adherence and minor bleedings
Data regarding adherence and minor bleeding on direct oral anticoagulants in everyday life are still sparse. Inclusion criteria: treatment initiated...
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Comparison of vitamin K and non-vitamin K oral anticoagulants and the bleeding frequency in the emergency department
IntroductionSafety studies of anticoagulant therapy have so far been conducted on many subjects in controlled conditions (i.e., clinically monitored)...
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Direct Oral Anticoagulants: Navigating Through Clinical Challenges
PurposeDirect oral anticoagulants (DOACs) have been approved, for over a decade, by both European and American medicine agencies, for treatment and...
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Characterization of direct oral anticoagulants use in adult hematopoietic stem cell transplant recipients
Direct oral anticoagulants (DOACs) for venous thromboembolism (VTE) treatment are of interest in oncology due to ease of administration and lack of...
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Non-vitamin K antagonist oral anticoagulants in adults with congenital heart disease
Despite an improved survival rate, cardiovascular accidents including thromboembolic events are a common cause of death in adults with congenital...
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Direct Oral Anticoagulants From Pharmacology to Clinical Practice
This book concisely covers the latest developments in the application of direct oral anticoagulants (DOACs) within cardiovascular medicine. It...
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Employing Real-World Evidence for the Economic Evaluation of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation in Thailand
BackgroundThis study aimed to assess the cost-effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) in comparison with warfarin using...
