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Dynamic change of gut microbiota in head and neck concurrent chemoradiotherapy patients and its potential value in the prediction of acute oral mucositis grade as well as quality of life
PurposeRadiotherapy is the major therapy for head and neck squamous cell carcinoma (HNSCC). However, whether gut microbiota changes in HNSCC patients...
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Acromegaly is associated with a distinct oral and gut microbiota
PurposeOur aim was to investigate the changes in the composition of oral and gut microbiota in patients with newly diagnosed acromegaly and their...
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Mouse IgA modulates human gut microbiota with inflammatory bowel disease patients
BackgroundThe imbalance of commensal bacteria is called dysbiosis in intestinal microflora. Secreted IgA in the intestinal lumen plays an important...
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Microbiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes
AimsThe purpose of this review is to explore the interconnected pathways of the microbiota-gut-brain axis (MGBA), focusing on the roles of the vagus...
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Oral-gut microbial transmission promotes diabetic coronary heart disease
BackgroundDiabetes is a predominant driver of coronary artery disease worldwide. This study aims to unravel the distinct characteristics of oral and...
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The relationship between the gut microbiota and thyroid disorders
Disorders of the thyroid gland are common, more prevalent in women than in men, and range from inflammatory to neoplastic lesions. Autoimmune thyroid...
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Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast genetic and metabolic potential of the gut microbiome...
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Gut microbiota in cancer: insights on microbial metabolites and therapeutic strategies
In recent years, the role of gut microbiota in cancer treatment has attracted substantial attention. It is now well established that gut microbiota...
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Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC is its intimate association with the gut microbiota, which...
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Gut microbiota and type 2 diabetes mellitus: a focus on the gut-brain axis
Type 2 diabetes mellitus (T2DM) has become one of the most serious public healthcare challenges, contributing to increased mortality and disability....
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Bridging the gap: associations between gut microbiota and psychiatric disorders
BackgroundGut microbiota plays a pivotal role in the gut-brain axis and can influence neurodevelopment and mental health outcomes. This review...
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Gut microbiota in overweight and obesity: crosstalk with adipose tissue
Overweight and obesity are characterized by excessive fat mass accumulation produced when energy intake exceeds energy expenditure. One plausible way...
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Gut microbiota and acute kidney injury: immunological crosstalk link
The gut microbiota, often called the "forgotten organ," plays a crucial role in bidirectional communication with the host for optimal physiological...
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Critical role of the gut microbiota in immune responses and cancer immunotherapy
The gut microbiota plays a critical role in the progression of human diseases, especially cancer. In recent decades, there has been accumulating...
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Differential oral and gut microbial structure related to systemic metabolism in kidney stone patients
ObjectivesTo investigate the role of the oral and gut microbiome related to systemic metabolism and clinical parameters in various types of kidney...
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Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It’s also the leading cause of liver-related...
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Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: a pilot study
PurposeMounting evidence suggests that the gut microbiome influences radiotherapy efficacy and toxicity by modulating immune signalling. However, its...
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Toxicity assessment of Cucurbita pepo cv Dayangua and its effects on gut microbiota in mice
BackgroundCucurbita pepo cv Dayangua (CPD) is an edible plant with diverse pharmacological properties. The current research on CPD has primarily...
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Altered oral microbiota and immune dysfunction in Chinese elderly patients with schizophrenia: a cross-sectional study
Schizophrenia (SZ) is a complex psychiatric neurodevelopmental disorder with uncertain etiology and pathogenesis. Increasing evidence has recognized...
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Targeting the Filipino gut microbiota in the management of hypertension
BackgroundHypertension is a major health problem in the Philippines, being the second leading disease and the second leading factor driving the most...