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AI-Based Optimal Treatment Strategy Selection for Female Infertility for First and Subsequent IVF-ET Cycles
Over the last 20 years, China’s infertility rate has risen from 3% to 12.5%–15%. Infertility has become the third largest disease following cancer...
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Identifying the optimal treatment strategy in patients with resectable non-cardia gastric cancer
BackgroundMultimodal treatment strategy including perioperative chemotherapy (PEC), postoperative chemoradiation therapy (POCR), and postoperative...
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What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?
Soft tissue sarcomas (STS) are rare tumours of mesenchymal origin, most commonly occurring in the extremity but also in the retroperitoneum. The...
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Which treatment strategy is optimal for acute left-sided malignant colonic obstruction? A Bayesian meta-analysis
PurposeThis study aimed to determine the best treatment for acute left-sided malignant colonic obstruction (ALMCO) among emergency surgery (ES),...
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A mathematical simulation model to determine the optimal endoscopic screening strategy for detection of H. pylori-naïve gastric neoplasms
BackgroundThe effectiveness of esophagogastroduodenoscopy (EGD) screening in cohorts with low Helicobacter pylori prevalence is unknown. This study...
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Optimal surgical management strategy for treatment of primary anorectal malignant melanoma—a systematic review and meta-analysis
BackgroundPrimary mucosal anorectal malignant melanoma (AMM) is an invasive malignancy with poor survival. Management options have been variable, due...
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Multiple dimensions of radiographic reconstruction for the optimal operative strategy of sacral meningeal cysts
Background and purposeThe contents and subtypes of sacral cysts are sophisticated in many cases. We applied multiple dimensional magnetic resonance...
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Optimal treatment strategy after first-line induction therapy in advanced HER2-positive oeso-gastric adenocarcinoma—a retrospective, international, multicentric AGEO study
BackgroundThe optimal treatment strategy after first-line induction therapy in advanced HER2-positive oeso-gastric adenocarcinoma (OGA) remains...
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The optimal antithrombotic strategy for post-stroke patients with atrial fibrillation and extracranial artery stenosis—a nationwide cohort study
BackgroundIn post-stroke atrial fibrillation (AF) patients who have indications for both oral anticoagulant (OAC) and antiplatelet agent (AP), e.g.,...
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The optimal vaccination strategy to control COVID-19: a modeling study in Wuhan City, China
BackgroundReaching optimal vaccination rates is an essential public health strategy to control the coronavirus disease 2019 (COVID-19) pandemic. This...
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What is the optimal (neo)adjuvant strategy of extremity high-risk soft tissue sarcomas (ESTS)?
Currently, the standard treatment for extremity high-risk soft tissue sarcomas (ESTS) combines surgery and pre- or post-op radiation therapy (RT). In...
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Intravascular ultrasound-based decision tree model for the optimal endovascular treatment strategy selection of femoropopliteal artery disease—results from the ONION Study-
BackgroundThe role of catheter-based imaging in peripheral interventions for lower extremity artery disease (LEAD) has increased with percutaneous...
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Optimal Therapeutic Strategy for PD-L1 Negative Metastatic Non-Small Cell Lung Cancer: A Decision-Making Guide Based on Clinicopathological and Molecular Features
Strategies using immune checkpoint inhibitors (ICI), which can enhance antitumor immune responses, have revolutionized the lung cancer therapeutic...
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A strategy for optimal fitting of multiplicative and additive hazards regression models
BackgroundIn survival analysis, data can be modeled using either a multiplicative hazards regression model (such as the Cox model) or an additive...
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High vs low CPAP strategy with aerosolized calfactant in preterm infants with respiratory distress syndrome
BackgroundOptimal CPAP strategy to prevent CPAP failure defined as need for endotracheal intubation is unknown.
ObjectiveTo evaluate the risk of...
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Surgical strategy for intravenous leiomyomatosis spreading from uterine to the right atrium presenting with recurrent syncope
Uterine leiomyoma invading internal iliac vein and consequently disseminating into the right atrium is an extremely rare condition, and surgical...
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Polypill Strategy in Secondary Cardiovascular Prevention
Purpose of ReviewThe polypill strategy, originally developed to improve medication adherence, has demonstrated efficacy in improving baseline...
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The Usefulness of Total Tumor Volume as a Prognostic Factor and in Selecting the Optimal Treatment Strategy of Chemotherapeutic Intervention in Patients with Colorectal Liver Metastases
BackgroundFew reports have discussed the association between total tumor volume (TTV) and prognosis in patients with colorectal liver metastases...