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  1. AI-Based Optimal Treatment Strategy Selection for Female Infertility for First and Subsequent IVF-ET Cycles

    Over the last 20 years, China’s infertility rate has risen from 3% to 12.5%–15%. Infertility has become the third largest disease following cancer...

    Renjie Wang, Wei Pan, ... Shujie Liao in Journal of Medical Systems
    Article 16 August 2023
  2. Identifying the optimal treatment strategy in patients with resectable non-cardia gastric cancer

    Background

    Multimodal treatment strategy including perioperative chemotherapy (PEC), postoperative chemoradiation therapy (POCR), and postoperative...

    Pranay S. Ajay, Raja Kumaran Rajamanickam, ... Mihir M. Shah in Surgical Endoscopy
    Article 07 November 2023
  3. What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?

    Soft tissue sarcomas (STS) are rare tumours of mesenchymal origin, most commonly occurring in the extremity but also in the retroperitoneum. The...

    Paulina Chmiel, Piotr Rutkowski, ... Anna M. Czarnecka in Current Treatment Options in Oncology
    Article Open access 29 May 2024
  4. Which treatment strategy is optimal for acute left-sided malignant colonic obstruction? A Bayesian meta-analysis

    Purpose

    This study aimed to determine the best treatment for acute left-sided malignant colonic obstruction (ALMCO) among emergency surgery (ES),...

    Kaibo Ouyang, Zifeng Yang, ... Yong Li in International Journal of Colorectal Disease
    Article 17 August 2023
  5. A mathematical simulation model to determine the optimal endoscopic screening strategy for detection of H. pylori-naïve gastric neoplasms

    Background

    The effectiveness of esophagogastroduodenoscopy (EGD) screening in cohorts with low Helicobacter pylori prevalence is unknown. This study...

    Fumiaki Ishibashi, Kosuke Okusa, ... Sho Suzuki in Gastric Cancer
    Article 27 June 2024
  6. Optimal surgical management strategy for treatment of primary anorectal malignant melanoma—a systematic review and meta-analysis

    Background

    Primary mucosal anorectal malignant melanoma (AMM) is an invasive malignancy with poor survival. Management options have been variable, due...

    Hugo C. Temperley, Niall J. O’Sullivan, ... Michael E. Kelly in Langenbeck's Archives of Surgery
    Article 04 November 2022
  7. Multiple dimensions of radiographic reconstruction for the optimal operative strategy of sacral meningeal cysts

    Background and purpose

    The contents and subtypes of sacral cysts are sophisticated in many cases. We applied multiple dimensional magnetic resonance...

    Qianquan Ma, **gcheng **e, ... Jianjun Sun in European Spine Journal
    Article Open access 10 August 2022
  8. Optimal treatment strategy after first-line induction therapy in advanced HER2-positive oeso-gastric adenocarcinoma—a retrospective, international, multicentric AGEO study

    Background

    The optimal treatment strategy after first-line induction therapy in advanced HER2-positive oeso-gastric adenocarcinoma (OGA) remains...

    Elisabeth S. Bergen, Lorenzo Pilla, ... Aziz Zaanan in Gastric Cancer
    Article 07 March 2023
  9. The optimal antithrombotic strategy for post-stroke patients with atrial fibrillation and extracranial artery stenosis—a nationwide cohort study

    Background

    In post-stroke atrial fibrillation (AF) patients who have indications for both oral anticoagulant (OAC) and antiplatelet agent (AP), e.g.,...

    Chuan-Tsai Tsai, Yi-Hsin Chan, ... Tze-Fan Chao in BMC Medicine
    Article Open access 13 March 2024
  10. The optimal vaccination strategy to control COVID-19: a modeling study in Wuhan City, China

    Background

    Reaching optimal vaccination rates is an essential public health strategy to control the coronavirus disease 2019 (COVID-19) pandemic. This...

    Ze-yu Zhao, Yan Niu, ... Tian-mu Chen in Infectious Diseases of Poverty
    Article Open access 28 December 2021
  11. What is the optimal (neo)adjuvant strategy of extremity high-risk soft tissue sarcomas (ESTS)?

    Currently, the standard treatment for extremity high-risk soft tissue sarcomas (ESTS) combines surgery and pre- or post-op radiation therapy (RT). In...

    Saoussane Kharmoum, **ane Kharmoum, ... Mohammed Shimi in Medical Oncology
    Article 12 December 2023
  12. Intravascular ultrasound-based decision tree model for the optimal endovascular treatment strategy selection of femoropopliteal artery disease—results from the ONION Study-

    Background

    The role of catheter-based imaging in peripheral interventions for lower extremity artery disease (LEAD) has increased with percutaneous...

    Yuko Yazu, Masahiko Fujihara, ... Yusuke Tomoi in CVIR Endovascular
    Article Open access 06 October 2022
  13. Optimal Therapeutic Strategy for PD-L1 Negative Metastatic Non-Small Cell Lung Cancer: A Decision-Making Guide Based on Clinicopathological and Molecular Features

    Strategies using immune checkpoint inhibitors (ICI), which can enhance antitumor immune responses, have revolutionized the lung cancer therapeutic...

    Mariana Malvicini, Maysa Silveira Vilbert, ... Manglio M. Rizzo in Current Treatment Options in Oncology
    Article 06 October 2023
  14. A strategy for optimal fitting of multiplicative and additive hazards regression models

    Background

    In survival analysis, data can be modeled using either a multiplicative hazards regression model (such as the Cox model) or an additive...

    François Lefebvre, Roch Giorgi in BMC Medical Research Methodology
    Article Open access 06 May 2021
  15. High vs low CPAP strategy with aerosolized calfactant in preterm infants with respiratory distress syndrome

    Background

    Optimal CPAP strategy to prevent CPAP failure defined as need for endotracheal intubation is unknown.

    Objective

    To evaluate the risk of...

    D. C. Kaluarachchi, E. Gerday, ... S. Minton in Journal of Perinatology
    Article 09 April 2024
  16. Surgical strategy for intravenous leiomyomatosis spreading from uterine to the right atrium presenting with recurrent syncope

    Uterine leiomyoma invading internal iliac vein and consequently disseminating into the right atrium is an extremely rare condition, and surgical...

    Gengxu He, Tong Yao, ... Kai Zhou in Journal of Cardiothoracic Surgery
    Article Open access 15 April 2024
  17. Polypill Strategy in Secondary Cardiovascular Prevention

    Purpose of Review

    The polypill strategy, originally developed to improve medication adherence, has demonstrated efficacy in improving baseline...

    Alan De la Rosa, Kedzie Arrington, ... Prakrati C. Acharya in Current Cardiology Reports
    Article 01 April 2024
  18. The Usefulness of Total Tumor Volume as a Prognostic Factor and in Selecting the Optimal Treatment Strategy of Chemotherapeutic Intervention in Patients with Colorectal Liver Metastases

    Background

    Few reports have discussed the association between total tumor volume (TTV) and prognosis in patients with colorectal liver metastases...

    Yuhi Shimura, Shohei Komatsu, ... Takumi Fukumoto in Annals of Surgical Oncology
    Article 29 June 2023
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