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Investigation of the effects of Gamma Knife radiosurgery on optic pathways using diffusion tensor MRI within the first year after treatment
PurposeTo investigate the radiation-induced effects of Gamma Knife radiosurgery (GKRS) for sellar-parasellar tumors on optic pathways using DTI...
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Traumatic Optic Neuropathy: Challenges and Opportunities in Develo** Neuroprotective and Neuroregenerative Therapies
Purpose of ReviewTraumatic optic neuropathy (TON) is a devasting disorder that can result in irreversible vision loss. Understanding the current...
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Traumatic optic neuropathy management: a systematic review
BackgroundTraumatic optic neuropathy is classically described in up to 8% of patients with traumatic brain injury (TBI), but subclinical or...
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Maculopapillary Bundle Degeneration in Optic Neuropathies
Purpose of ReviewDegeneration of the maculopapillary bundle (MPB) is a prominent feature in a spectrum of optic neuropathies. MPB-selective...
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MOG antibody-associated optic neuritis
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is a demyelinating disorder, distinct from multiple sclerosis (MS) and...
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Glaucoma as a cause of optic nerve abnormalities on magnetic resonance imaging
Background/objectivesTo report a series of patients with glaucoma and optic nerve abnormalities on magnetic resonance imaging (MRI) in at least...
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Biomarker Defined Acute Optic Neuritis: A Review and Perspective
Purpose of reviewThis review provides a comprehensive summary of treatment options and management considerations for patients with acute inflammatory...
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Nerve fibre organisation in the human optic nerve and chiasm: what do we really know?
A recent anatomical study of the human optic chiasm cast doubt on the widespread assumption that nerve fibres travelling in the human optic nerve and...
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Activation of multiple Eph receptors on neuronal membranes correlates with the onset of optic neuropathy
BackgroundOptic neuropathy is a major cause of irreversible blindness, yet the molecular determinants that contribute to neuronal demise have not...
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Convolutional neural network-based classification of glaucoma using optic radiation tissue properties
BackgroundSensory changes due to aging or disease can impact brain tissue. This study aims to investigate the link between glaucoma, a leading cause...
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How far should I manage acute optic neuritis as an ophthalmologist? A United Kingdom perspective
Optic neuritis (ON) is an inflammation of or around the optic nerve, frequently caused by infectious or immune-mediated inflammatory disorders. In...
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Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch
BackgroundElevated intraocular pressure (IOP) is the main risk factor for glaucoma, which might cause the activation of astrocytes in optic nerve...
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Programmed axon death: a promising target for treating retinal and optic nerve disorders
Programmed axon death is a druggable pathway of axon degeneration that has garnered considerable interest from pharmaceutical companies as a...
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Evaluating patient-reported outcome measures (PROMs) for future clinical trials in adult patients with optic neuritis
ObjectiveTo search for and critically appraise the psychometric quality of patient-reported outcome measures (PROMs) developed or validated in optic...
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Cross-subject variability of the optic radiation anatomy in a cohort of 1065 healthy subjects
IntroductionOptic radiations are tracts of particular interest for neurosurgery, especially for temporal lobe resection, because their lesion is...
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Evaluating macular and optic nerve changes during Ramadan fasting by optical coherence tomography angiography-a prospective before-and-after study
PurposeDuring Ramadan, millions of Muslims fast from sunrise to sunset. Fasting influences the hormonal system, sympathetic activity, blood...
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Tocilizumab use for optic nerve compression in thyroid eye disease: a prospective longitudinal cohort
PurposeTo assess the effectiveness of tocilizumab in reverting the signs and symptoms of dysthyroid optic neuropathy (DON) in thyroid eye disease and...
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Portable multi-focal visual evoked potential diagnostics for multiple sclerosis/optic neuritis patients
PurposeMultiple sclerosis (MS) is a neuro-inflammatory disease affecting the central nervous system (CNS), where the immune system targets and...
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Ischemic optic neuropathy as first presentation in patient with m.3243 A > G MELAS classic mutation
BackgroundMitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a systemic disorder in which multi-organ...
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Assessment the neurodegenaration process of post-geniculate optic pathway in thalamic tumors using optical coherence tomography: Post-geniculate optic pathway in thalamic tumors
PurposeTo investigate the effect of thalamic tumors related to post-geniculate optic pathway and those of microsurgical removal on neurodegeneration...
