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Sample Size Requirements to Test Subgroup-Specific Treatment Effects in Cluster-Randomized Trials
Cluster-randomized trials (CRTs) often allocate intact clusters of participants to treatment or control conditions and are increasingly used to...
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Prospective pathway signaling and prognostic values of MicroRNA-9 in ovarian cancer based on gene expression omnibus (GEO): a bioinformatics analysis
ObjectiveMicroRNAs (miRNAs) play a vital role in the development of ovarian cancer (OC). The aim of this study to investigate the prognostic value...
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The sinking platform test: a novel paradigm to measure persistence in animal models
Persistence is the propensity to maintain goal-directed actions despite adversities. While this temperamental trait is crucial to mitigate depression...
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Which test for crossing survival curves? A user’s guideline
BackgroundThe exchange of knowledge between statisticians develo** new methodology and clinicians, reviewers or authors applying them is...
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The Auditory Brainstem Response (ABR) Test, Supplementary to Behavioral Tests for Evaluation of the Salicylate-Induced Tinnitus
Tinnitus is a symptom of various disorders that affects the quality of life of millions people. Given the significance of the access to an objective...
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Meta-Analysis of Acculturation and Suicide-Related Outcomes: A Test of the Immigrant Paradox
ObjectiveThis meta-analysis aimed to systematically test the relation between acculturation and suicide-related outcomes among immigrants, with...
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Power analyses for measurement model misspecification and response shift detection with structural equation modeling
PurposeStatistical power for response shift detection with structural equation modeling (SEM) is currently underreported. The present paper addresses...
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Clinical analysis on diagnostic accuracy of Bosch Vivalytic SARS-CoV-2 point-of-care test and evaluation of cycle threshold at admission for COVID-19 risk assessment
BackgroundPoint-of-care (POC) polymerase chain reaction (PCR) tests have the ability to improve testing efficiency in the Coronavirus disease 2019...
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Identification of candidate genes in ischemic cardiomyopathy by gene expression omnibus database
BackgroundIschemic cardiomyopathy (ICM) is one of the most usual causes of death worldwide. This study aimed to find the candidate gene for ICM.
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Test Anxiety and Poor Sleep: A Vicious Cycle
BackgroundTest anxiety may be better thought of as a biopsychosocial process affecting academic performance during the days leading up to an exam,...
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Bioinformatics analysis on multiple Gene Expression Omnibus datasets of the hepatitis B virus infection and its response to the interferon-alpha therapy
BackgroundHepatitis B virus (HBV) infection is a global health problem and interferon-alpha (IFN-α) is one of the effective therapies. However,...
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Establishment of dry chemistry based reference intervals of renal function test parameters for the adult population of Kaski District, Nepal
BackgroundReference intervals (RIs) for clinical chemistry test parameters are specific to the method of measurement and population under service....
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Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank
Psychiatric disorders are complex clinical conditions with large heterogeneity and overlap in symptoms, genetic liability and brain imaging...
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Assessment of fall-associated risk factors in the Muslim community-dwelling older adults of Peshawar, Khyber Pakhtunkhwa, Pakistan
BackgroundFalls are the third-leading cause of disability among the elderly population worldwide. It is multifactorial, and the occurrence of falls...
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Identification of transcription factors MYC and C/EBPβ mediated regulatory networks in heart failure based on gene expression omnibus datasets
BackgroundHeart failure is one of leading cause of death worldwide. However, the transcriptional profiling of heart failure is unclear. Moreover, the...
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Prognostic values and prospective pathway signaling of MicroRNA-182 in ovarian cancer: a study based on gene expression omnibus (GEO) and bioinformatics analysis
BackgroundOvarian carcinoma (OC) is a common cause of death among women with gynecological cancer. MicroRNAs (miRNAs) are believed to have vital...
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Does acute cannabidiol (CBD) use impair performance? A meta-analysis and comparison with placebo and delta-9-tetrahydrocannabinol (THC)
Cannabidiol (CBD) is widely used and believed to be non-intoxicating, lacking acute performance effects (e.g., non-impairing). However, a synthesis...
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Comparison of a thymine challenge test and endogenous uracil–dihydrouracil levels for assessment of fluoropyrimidine toxicity risk
PurposeStandard dosages of fluoropyrimidine chemotherapy result in severe toxicity in a substantial proportion of patients, however, routine...
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The Status of Evidence-Based Treatments for Moral Injury Syndrome: Review and Meta-analysis of Randomized Controlled Trials
Purpose of reviewThe goals of this report were to (a) review the empirical evidence of interventions for moral injury syndrome (MIS) symptoms, (b)...
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Does Test Anxiety Predispose Poor School-Related Wellbeing and Enhanced Risk of Emotional Disorders?
BackgroundPrevious studies have shown that children and adolescents who report high levels of test anxiety also report symptoms of, and meet clinical...