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Validation of prognostic and predictive value of total tumoral load after primary systemic therapy in breast cancer using OSNA assay
PurposeThis study aimed to validate the classification of breast cancer (BC) patients in progression risk groups based on total tumor load (TTL)...
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Value of total tumor load as a clinical and pathological factor in the prognosis of breast cancer patients receiving neoadjuvant treatment. Comparison of three populations with three different surgical approaches: NEOVATTL Pro 3 Study
PurposeThis study aimed to compare the prognosis in terms of disease-free survival (DFS) in three populations of women with breast cancer (BC)...
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Feasibility of Pooled One-Step Nucleic Acid Amplification for Molecular Staging of Pathologically Node-Negative Colon Cancer: A Prospective Multicenter Study
BackgroundAlthough conventional one-step nucleic acid amplification (OSNA) is a useful molecular-staging method, its complexity hinders its use in...
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Utility of the one-step nucleic acid amplification assay in sentinel node map** for early gastric cancer patients
BackgroundTo safely perform minimized gastrectomy based on sentinel node (SN) concept for early gastric cancer patients, intraoperative diagnostic...
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Prospective feasibility study for single-tracer sentinel node map** by ICG (indocyanine green) fluorescence and OSNA (one-step nucleic acid amplification) assay in laparoscopic gastric cancer surgery
BackgroundThe double-tracer method has been established for sentinel node (SN) map** in gastric cancer surgery. However, there remain several...
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Predictive and prognostic value of total tumor load in sentinel lymph nodes in breast cancer patients after neoadjuvant treatment using one-step nucleic acid amplification: the NEOVATTL study
ObjectiveTo evaluate the predictive and prognostic value of total tumor load (TTL) in sentinel lymph nodes (SLNs) in patients with infiltrating...
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Lymph Node Positivity in One-Step Nucleic Acid Amplification is a Prognostic Factor for Postoperative Cancer Recurrence in Patients with Stage II Colorectal Cancer: A Prospective, Multicenter Study
BackgroundFor colorectal cancer (CRC) patients, the standard histological lymph node (LN) evaluation has low sensitivity. Our previously developed...
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Two rare cases of endosal**iosis in the axillary sentinel lymph nodes: evaluation of immunohistochemical staining and one-step nucleic acid amplification (OSNA) assay in patients with breast cancer
Benign inclusions, such as endosal**iosis, in an axillary sentinel lymph node (SLN) can be misdiagnosed as metastatic breast carcinoma. However,...
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Performance of a new system using a one-step nucleic acid amplification assay for detecting lymph node metastases in breast cancer
One-step nucleic acid amplification (OSNA) for CK19 mRNA is an intraoperative diagnostic procedure for detection of lymph node metastasis. Automated...
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Omission of axillary lymph node dissection in breast cancer patients with micrometastasis or isolated tumor cells in sentinel lymph nodes: a 12-year experience in a tertiary breast unit
IntroductionAfter the IBCSG 23–01 trial, our breast center no longer performed axillary lymph node dissection (ALND) after detection of isolated...
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Comparison of CK-IHC assay on serial frozen sections, the OSNA assay, and in combination for intraoperative evaluation of SLN metastases in breast cancer
BackgroundIntraoperative evaluations of sentinel lymph node (SLN) metastases are performed for providing appropriate and immediate axillary...
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Budget Impact Analysis of Molecular Lymph Node Staging Versus Conventional Histopathology Staging in Colorectal Carcinoma
BackgroundThe presence of lymph node (LN) metastasis is a critical prognostic factor in colorectal cancer (CRC) patients and is also an indicator for...
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Indocyanine green-guided sentinel lymph node map** during laparoscopic surgery with vaginal cuff closure but no uterine manipulator for cervical cancer
BackgroundLymph node metastasis is a critical prognostic factor in cervical cancer. Considering the potential complications of lymphadenectomy and...
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A case of breast squamous cell carcinoma following breast augmentation with liquid silicone injection after 16 years
BackgroundBreast augmentation has been linked to various complications, including cancerous tumors. The majority type of breast cancer associated...
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Diagnostic criteria of sentinel lymph node micrometastasis or macrometastasis based on tissue rinse liquid-based cytology in gynecological cancer
ObjectiveThis study aimed to establish intraoperative diagnostic criteria of sentinel lymph node (SLN) micro-/macrometastasis on the basis of tissue...
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Lymphadenectomy in Endometrial Cancers—A Review
Most endometrial cancers are diagnosed in an early stage, and nearly three-fourths do not require any lymph node clearance. Surgical staging is...
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Nomogram to predict non-sentinel lymph node status using total tumor load determined by one-step nucleic acid amplification: first report from Thailand
BackgroundAxillary staging is a significant prognostic factor often used to determine the treatment course for breast cancer. One-step nucleic acid...
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Survey of the clinical practice pattern of using sentinel lymph node biopsy in patients with gynecological cancers in Japan: the Japan Society of Gynecologic Oncology study
BackgroundSentinel lymph node (SN) biopsy is essential for evaluating survival and minimal treatment-related morbidity associated with cervical,...