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Feasibility of spectral CT–derived extracellular volume fraction for differentiating aldosterone-producing from nonfunctioning adrenal nodules
ObjectiveTo assess the feasibility of spectral CT–derived extracellular volume (ECV) for differentiating aldosterone-producing nodules (APN) from...
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Nonfunctioning adrenal incidentalomas with cortisol post-dexamethasone suppression test >0.9 µg/dL have a higher prevalence of cardiovascular disease than those with values ≤0.9 µg/dL
PurposeTo analyze the differences in the cardiometabolic profile in patients with nonfunctioning adrenal incidentalomas (NFAI) with...
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Adrenalectomy improves blood pressure control in nonfunctioning adrenal incidentalomas and glycemic and lipid control in patients with autonomous cortisol secretion
PurposeTo compare the evolution of the cardiometabolic parameters in patients with nonfunctioning adrenal incidentalomas (NFAI) and autonomous...
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Adrenal cavernous hemangioma misdiagnosed as pheochromocytoma: a case report
BackgroundAdrenal hemangioma is a rare benign adrenal tumor that is usually misdiagnosed preoperatively. We here present a case of adrenal cavernous...
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Novel germline variants of CDKN1B and CDKN2C identified during screening for familial primary hyperparathyroidism
PurposeCDKN1B mutations were established as a cause of multiple endocrine neoplasia 4 (MEN4) syndrome in patients with MEN1 phenotype without a...
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An update on the development of concepts, diagnostic criteria, and challenging issues for neuroendocrine neoplasms across different digestive organs
Digestive neuroendocrine neoplasms (NENs) are a group of heterogeneous neoplasms found throughout the digestive tract, with different behaviour and...
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A case of atypical reninoma with mild hypertension and normal plasma renin activity but elevated plasma renin concentration
BackgroundReninoma is a rare, benign renal neoplasm. Typical clinical features include severe hypertension, secondary hyperaldosteronism,...
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Posterior pituitary tumours: the spectrum of a unique entity. A clinical and histological study of a large case series
PurposeIn 2017, the WHO established that pituicytoma, granular cell tumour (GCT) and spindle cell oncocytoma (SCO) are posterior pituitary tumours...
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PET/MRI imaging in neuroendocrine neoplasm
Molecular imaging plays a vital role in the management of neuroendocrine neoplasms (NENs). Somatostatin receptor (SSTR) PET is critical for...
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Adrenocortical carcinoma: presentation and outcome of a contemporary patient series
BackgroundAdrenocortical carcinoma (ACC) is a rare endocrine carcinoma with poor 5-year survival rates of < 40%. According to the literature, ACC is...
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A novel germline mutation at exon 10 of MEN1 gene: a clinical survey and positive genotype-phenotype analysis of a MEN1 Italian family, including monozygotic twins
ContextClinical phenotype variability in MEN1 syndrome exists and evidence for an established genotype-phenotype is lacking. However, a higher...
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Fertility issues in aggressive pituitary tumors
The management of aggressive pituitary adenomas represents a special clinical challenge, and usually involves a combination of surgery, radiotherapy...
