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Nicotine dependence and insula subregions: functional connectivity and cue-induced activation
Nicotine dependence is a major predictor of relapse in people with Tobacco Use Disorder (TUD). Accordingly, therapies that reduce nicotine dependence...
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Family functioning and nicotine dependence among smoking fathers: a cross-sectional study
BackgroundNicotine dependence is a significant public health issue, and understanding the factors associated with nicotine dependence in this...
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Tobacco Dependence A Comprehensive Guide to Prevention and Treatment
This book is a guide to pharmacotherapy treatment of tobacco dependence. The 2020 American Thoracic Society clinical practice guidelines on treating...
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Nicotine dependence and associated factors among persons who use electronic e-cigarettes in Malaysia - an online survey
BackgroundNicotine dependence, factors associated with dependence, and self-reported side effects among people who use e-cigarettes are scarce in...
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Pain and Menthol Use Are Related to Greater Nicotine Dependence Among Black Adults Who Smoke Cigarettes at Wave 5 (2018–2019) of the Population Assessment of Tobacco and Health (PATH) Study
Burdens related to pain, smoking/nicotine dependence, and pain-smoking comorbidity disproportionately impact Black Americans, and menthol cigarette...
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Managing missing items in the Fagerström Test for Nicotine Dependence: a simulation study
BackgroundThe Fagerström Test for Nicotine Dependence (FTND) is frequently used to assess the level of smokers’ nicotine dependence; however, it is...
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Individual variations in motives for nicotine self-administration in male rats: evidence in support for a precision psychopharmacology
The significant heterogeneity in smoking behavior among smokers, coupled with the inconsistent efficacy of approved smoking cessation therapies,...
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Risk and Protective Factors Associated with Electronic Nicotine Delivery System Use in a Hispanic College Sample
Young Hispanics are at greater risk of electronic nicotine delivery system (ENDS) use compared to non-Hispanic individuals. A lack of a consistent...
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Comparison of brain nicotine accumulation from traditional combustible cigarettes and electronic cigarettes with different formulations
Rapid brain accumulation is critical for the acute reinforcing effects of nicotine. Although nicotine formulation (free-base vs. protonated or salt)...
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Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system
The majority of lifetime smokers begin using nicotine during adolescence, a critical period of brain development wherein neural circuits critical for...
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Assessment of nicotine dependence among tobacco users visiting outreach programs in Dharan, Nepal: a cross-sectional study
BackgroundNicotine is a highly addictive substance present in tobacco. This study was conducted to assess the level of nicotine dependence among...
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Factors influencing JUUL e-cigarette nicotine vapour-induced reward, withdrawal, pharmacokinetics and brain connectivity in rats: sex matters
Though va** likely represents a safer alternative to smoking, it is not without risks, many of which are not well understood, especially for...
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Understanding the Impact of Flavors on Va** and Nicotine Addiction-Related Behaviors
Purpose of reviewThe central thesis of this review is to highlight how major chemical flavoring agents used in electronic nicotine delivery systems...
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Disrupted brain state dynamics in opioid and alcohol use disorder: attenuation by nicotine use
Substance use disorder (SUD) is a chronic relapsing disorder with long-lasting changes in brain intrinsic networks. While most research to date has...
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Characterising smoking and nicotine use behaviours among women of reproductive age: a 10-year population study in England
BackgroundTobacco smoking affects women’s fertility and is associated with substantial risks of adverse pregnancy outcomes. This study explored...
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The controversial effect of smoking and nicotine in SARS-CoV-2 infection
The effects of nicotine and cigarette smoke in many diseases, notably COVID-19 infection, are being debated more frequently. The current basic data...
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Subregion specific neuroadaptations in the female rat striatum during acute and protracted withdrawal from nicotine
Epidemiological studies and clinical observations suggest that nicotine, a major contributor of the global burden of disease, acts in a partially sex...
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Comparison of brain nicotine uptake from electronic cigarettes and combustible cigarettes
Brain accumulation rate and magnitude are critical for the acute reinforcing effects of nicotine. Despite electronic cigarettes’ (E-cigs) appeal as...
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Tobacco and nicotine use
Tobacco smoking is a major determinant of preventable morbidity and mortality worldwide. More than a billion people smoke, and without major...
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Underreporting of non-study cigarette use by study participants confounds the interpretation of results from ambulatory clinical trial of reduced nicotine cigarettes
BackgroundAs part of its comprehensive plan to significantly reduce the harm from tobacco products, the US Food and Drug Administration is...
