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Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction
AimsMyocardial infarction (MI) is a major cause of death. Nicotinamide adenine dinucleotide (NAD + ) is a coenzyme in oxidative phosphorylation and...
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NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
Purpose of ReviewNAD+ is a vital molecule that takes part as a redox cofactor in several metabolic reactions besides being used as a substrate in...
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Nicotinamide mononucleotide, a potential future treatment in ocular diseases
PurposeThe burden of ocular diseases has been gradually increasing worldwide. Various factors are suggested for the development and progression of...
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Insulin and glycolysis dependency of cardioprotection by nicotinamide riboside
Decreased nicotinamide adenine dinucleotide (NAD + ) levels contribute to various pathologies such as ageing, diabetes, heart failure and...
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Nicotinamide protects against diabetic kidney disease through regulation of Sirt1
PurposeTo investigate the effect of nicotinamide (Nam) on diabetic kidney disease (DKD) in mice and explore its mechanism.
MethodsThirty DBA/2 J...
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Nicotinamide-based agglomerates of ibuprofen: formulation, solid state characterization and evaluation of tableting performance with in-silico investigation
BackgroundThe objective of the present investigation was to obtain directly compressible agglomerates of ibuprofen with nicotinamide by a...
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Oral nicotinamide for non-melanoma skin cancers: A review
There has been much interest in the role of oral nicotinamide supplementation in reducing the incidence of non-melanoma skin cancers. This article...
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Nicotinamide Mononucleotide improves oocyte maturation of mice with type 1 diabetes
BackgroundThe number of patients with type 1 diabetes rises rapidly around the world in recent years. Maternal diabetes has a detrimental effect on...
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Nicotinamide Riboside, an NAD + Precursor, Protects Against Cardiac Mitochondrial Dysfunction in Fetal Guinea Pigs Exposed to Gestational Hypoxia
Gestational hypoxia inhibits mitochondrial function in the fetal heart and placenta contributing to fetal growth restriction and organ dysfunction....
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Antioxidant effect of nicotinamide mononucleotide in tendinopathy
BackgroundA link between tendinopathy and oxidative stress has been recently reported. Nicotinamide mononucleotide (NMN) is a precursor of...
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Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD+/SIRT3 pathway
Emerging evidence suggests that mitochondria play a central role in mental health disorders including schizophrenia. Here we investigated whether...
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Nicotinamide Riboside Improves Enteric Neuropathy in Streptozocin-Induced Diabetic Rats Through Myenteric Plexus Neuroprotection
BackgroundDiabetes Mellitus causes a systemic oxidative stress due in part to the hyperglycemia and the reactive oxygen species generated. Up to 75%...
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Longitudinal Study of Plasma Visfatin/Nicotinamide Phosphoribosyltransferase (NAMPT) Levels in Healthy Pregnant Women
Visfatin/nicotinamide phosphorybosil transferase (NAMPT) is a novel adipocytokine with potential roles in the pathophysiology of metabolic disorders,...
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The HF-AF ENERGY Trial: Nicotinamide Riboside for the Treatment of Atrial Fibrillation in Heart Failure Patients
BackgroundThe presence of atrial fibrillation (AF) in heart failure (HF) patients with reduced ejection fraction is common and associated with an...
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Effects of nicotinamide on follicular development and the quality of oocytes
BackgroundNicotinamide (NAM) is an important antioxidant, which is closely related to female fertility, but its role has not been clearly elucidated....
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Serum nicotinamide phosphoribosyltransferase as a novel biomarker for non-traumatic osteonecrosis of the femoral head
ObjectiveThe aim of this study was to investigate the potential role of serum nicotinamide phosphoribosyltransferase (NAMPT) in non-traumatic...