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The roles of the kynurenine pathway in COVID-19 neuropathogenesis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the highly contagious respiratory disease Corona Virus...
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Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management
People living with HIV are affected by the chronic consequences of neurocognitive impairment (NCI) despite antiretroviral therapies that suppress...
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Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells
Duck Tembusu virus (DTMUV) is a neurotropic virus in the genus Flavivirus that causes massive economic losses to the poultry industry in China and...
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Neuroimaging the Neuropathogenesis of HIV
Purpose of ReviewThis review highlights neuroimaging studies of HIV conducted over the last 2 years and discusses how relevant findings further our...
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Role of T Lymphocytes in HIV Neuropathogenesis
Purpose of ReviewThe purpose of this review is to summarize the current knowledge on the role of CD4 + T lymphocytes leading to HIV assault and...
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Pathogenesis of Fungal Infections in the Central Nervous System: Host and Pathogen Factors in Neurotropism
Purposeof ReviewFungal CNS infections (CNS-FIs) are associated with significant morbidity and mortality, especially in immunocompromised individuals:...
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Update on Central Nervous System Effects of the Intersection of HIV-1 and SARS-CoV-2
Purpose of ReviewResearch has shown myriad neurologic and mental health manifestations during the acute and subsequent stages of COVID-19 in people...
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Postoperative delirium in the elderly: the potential neuropathogenesis
Postoperative delirium (POD) is a neurobehavioral syndrome caused by dysfunction of neural activity mainly in elderly people. POD is not uncommon,...
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Viral protein R (Vpr)-induced neuroinflammation and its potential contribution to neuronal dysfunction: a sco** review
HIV-associated neurocognitive disorders (HAND) are the result of the activity of HIV-1 within the central nervous system (CNS). While the...
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An Update on Postoperative Delirium: Clinical Features, Neuropathogenesis, and Perioperative Management
Purpose of ReviewWe present a focused review on postoperative delirium for anesthesiologists, encompassing clinical features, neuropathogenesis,...
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Immunopathogenesis of viral infections in neurological autoimmune disease
Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-antigens. Several factors play a role in inducing...
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Update on Central Nervous System Effects of HIV in Adolescents and Young Adults
Purpose of Review.Behaviorally acquired (non-perinatal) HIV infection during adolescence and young adulthood occurs in the midst of key brain...
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COVID-19: A primer for Neuroradiologists
The potential for central nervous system (CNS) involvement in coronavirus disease 2019 (COVID-19) is a matter of grave concern and there is a...
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The association between gut microbiota and postoperative delirium in patients
Postoperative delirium is a common postoperative complication in older patients, and its pathogenesis and biomarkers remain largely undetermined. The...
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Advances in the Experimental Models of HIV-Associated Neurological Disorders
Purpose of ReviewInvolvement of the central nervous system (CNS) in HIV-1 infection is commonly associated with neurological disorders and cognitive...
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Central Nervous System Impact of Perinatally Acquired HIV in Adolescents and Adults: an Update
Purpose of ReviewPerinatally acquired HIV infection (PHIV) can confer neurodevelopmental risk. As children with PHIV increasingly survive through...
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Emerging Single-cell Approaches to Understand HIV in the Central Nervous System
Purpose of ReviewThis review highlights emerging single-cell sequencing methods relevant to translational studies of HIV in the central nervous...
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Ramelteon and suvorexant for postoperative delirium in elderly patients with esophageal cancer
BackgroundThere is no clear evidence on the prevention of postoperative delirium with pharmacotherapy in elderly patients with esophageal cancer....
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Developments in Neuroprotection for HIV-Associated Neurocognitive Disorders (HAND)
Purpose of ReviewReducing the risk of HIV-associated neurocognitive disorders (HAND) is an elusive treatment goal for people living with HIV....
