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Central neuropathic pain
Central neuropathic pain arises from a lesion or disease of the central somatosensory nervous system such as brain injury, spinal cord injury,...
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Pain-resolving immune mechanisms in neuropathic pain
Interactions between the immune and nervous systems are of central importance in neuropathic pain, a common and debilitating form of chronic pain...
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Effects of interdisciplinary pain rehabilitation programs on neuropathic and non-neuropathic chronic pain conditions – a registry-based cohort study from Swedish Quality Registry for Pain Rehabilitation (SQRP)
Background and aimNeuropathic pain arises as a direct consequence of a lesion or disease affecting the somatosensory system. Pharmacological...
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Advances in the Treatment of Neuropathic Pain by Sympathetic Regulation
Purpose of ReviewTo explore the mechanism and therapeutic effect of sympathetic nerve regulation on neuropathic pain.
Recent FindingsA comprehensive...
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Corneal Neuropathic Pain: A Patient and Physician Perspective
Corneal neuropathic pain (CNP) is a debilitating condition characterized by pain in the absence of a noxious stimulus. Symptoms such as ocular...
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The sensitivity and specificity of using the McGill pain subscale for diagnosing neuropathic and non-neuropathic chronic pain in the total joint arthroplasty population
BackgroundThe purpose of this study was to describe the diagnostic performance of the Neuropathic Pain Subscale of McGill [NP-MPQ (SF-2)] and the...
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Role of Integrative Health on Neuropathic Pain
Purpose of ReviewPatients diagnosed with neuropathic pain experience continuous or intermittent spontaneous pain throughout their lives....
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Neuropathic Pain and Spinal Cord Injury: Management, Phenotypes, and Biomarkers
Chronic neuropathic pain after a spinal cord injury (SCI) continues to be a complex condition that is difficult to manage due to multiple underlying...
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Notch signaling pathway: a new target for neuropathic pain therapy
The Notch gene, a highly evolutionarily conserved gene, was discovered approximately 110 years ago and has been found to play a crucial role in the...
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A Comparison of Neuropathic Pain Experiences Among Paralympic Versus Recreational Athletes with Spinal Cord Injury
BackgroundIndividuals with spinal cord injury (SCI) report high levels of neuropathic pain. Current treatment options are primarily pharmaceutical,...
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Corneal neuropathic pain: a review to inform clinical practice
Corneal neuropathic pain (CNP) is a poorly defined disease entity characterised by an aberrant pain response to normally non-painful stimuli and...
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Pharmacological and Non-pharmacological Approaches for the Management of Neuropathic Pain in Multiple Sclerosis
Multiple sclerosis is a chronic inflammatory disease that affects the central nervous system and can cause various types of pain including ongoing...
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Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain
Tricyclic antidepressants (TCAs), such as desipramine (DMI), are effective at managing neuropathic pain symptoms but often take several weeks to...
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Functional ability in knee osteoarthritis: role of neuropathic pain and central sensitization
BackgroundPain in osteoarthritis (OA) has been attributed traditionally to local tissue injury causing ‘nociceptive pain’. However, recent studies...
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Current trends in the medical treatment of neuropathic low back pain: a Swedish registry-based study of 1.7 million people
BackgroundLow back pain, a common problem worldwide, causes more global disability than any other condition and is associated with high costs to...
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Pathogenesis of Neuropathic Pain Diagnosis and Treatment
This comprehensive source on the pathogenic origins of neuropathic pain covers the detailed molecular bases of the currently known neuropathies as...
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Coexistence of neuropathic corneal pain, corneal nerve abnormalities, depression, and low quality of life
PurposeTo evaluate the quality of life (QoL), mental health conditions and corneal morphology in neuropathic corneal pain (NCP) subjects without a...
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A clinical approach to the investigation and management of long COVID associated neuropathic pain
COVID–19 has been associated with a wide range of ongoing symptoms following recovery from the acute SARS-CoV-2 infection. Around one in three people...
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Advances in Chronic and Neuropathic Pain
This book is an in depth guide to chronic and neuropathic pain. The issue of chronic and neuropathic pain is very prevalent, yet only a fraction of...
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Maximizing treatment efficacy through patient stratification in neuropathic pain trials
Treatment of neuropathic pain remains inadequate despite the elucidation of multiple pathophysiological mechanisms and the development of promising...
