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Natural products in the management of neurodegenerative diseases
Neurodegenerative diseases represent one of the utmost imperative well-being health issues and apprehensions due to their escalating incidence of...
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Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast genetic and metabolic potential of the gut microbiome...
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Management of Dysphagia in Neurodegenerative Disease
PurposeThe purpose of this review was to provide an overview of approaches to dysphagia management for patients with neurodegenerative disease.
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Exosomes for neurodegenerative diseases: diagnosis and targeted therapy
Purpose of ReviewNeurodegenerative diseases are still challenging clinical issues, with no curative interventions available and early, accurate...
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Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets
Microglia activation is observed in various neurodegenerative diseases. Recent advances in single-cell technologies have revealed that these reactive...
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Extracellular protein homeostasis in neurodegenerative diseases
The protein homeostasis (proteostasis) system encompasses the cellular processes that regulate protein synthesis, folding, concentration, trafficking...
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Retinale OCT-Biomarker und neurodegenerative Erkrankungen des zentralen Nervensystems jenseits der Alzheimer-Krankheit
BackgroundOptical coherence tomography (OCT) biomarkers are increasingly used by neurologists, psychiatrists, and ophthalmologists for the diagnosis,...
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Copper Metabolism and Cuproptosis: Molecular Mechanisms and Therapeutic Perspectives in Neurodegenerative Diseases
Copper is an essential trace element, and plays a vital role in numerous physiological processes within the human body. During normal metabolism, the...
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Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies
Neurodegenerative pathologies such as Alzheimer disease neuropathologic change (ADNC), Lewy body disease (LBD), limbic-predominant age-related TDP-43...
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Utilizing neurodegenerative markers for the diagnostic evaluation of amyotrophic lateral sclerosis
BackgroundAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive deterioration of upper and lower motor...
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Cognitive Interventions for Neurodegenerative Disease
Purpose of ReviewTo critically review recent research in the development of non-pharmacological interventions to improve cognitive functioning in...
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Healthy blood, healthy brain: a window into understanding and treating neurodegenerative diseases
Our limited understanding of complex neurodegenerative disorders has held us back on the development of efficient therapies. While several approaches...
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Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions
Multimodal biomarkers may identify former contact sports athletes with repeated concussions and at risk for dementia. Our study aims to investigate...
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Targeting NLRP3 inflammasome for neurodegenerative disorders
Neuroinflammation is a key pathological feature in neurological diseases, including Alzheimer’s disease (AD). The nucleotide-binding domain...
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Detection of episodic nocturnal hypercapnia in patients with neurodegenerative disorders
PurposeEpisodic nocturnal hypercapnia (eNH) in transcutaneous carbon dioxide pressure (PtcCO 2 ) corresponding to rapid eye movement sleep...
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Insights into AlphaFold’s breakthrough in neurodegenerative diseases
Neurodegenerative diseases (ND) are disorders of the central nervous system (CNS) characterized by impairment in neurons’ functions, and complete...
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Associations of cardiovascular risk factors and lifestyle behaviors with neurodegenerative disease: a Mendelian randomization study
Previous observational studies reported that midlife clustering of cardiovascular risk factors and lifestyle behaviors were associated with...
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Flanagan’s condensed protocol for neurodegenerative diseases. Implementation in a clinical autopsy setting with partial supervision of a neuropathologist
The Condensed Protocol (CP) was originally developed for the evaluation of Alzheimer’s Disease (AD) and other neurodegenerative diseases as a...
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Molecular Imaging of Neurodegenerative Disorders
This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of...
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G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders
Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors. Identifying treatment targets is challenging because the...
