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Clinical prediction rules for the diagnosis of neuritis in leprosy
BackgroundDiagnosing neuritis in leprosy patients with neuropathic pain or chronic neuropathy remains challenging since no specific laboratory or...
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Application of a physiotherapeutic protocol associated with photobiomodulation for the treatment of leprosy patients
Leprosy is a chronic infectious disease characterized by acute inflammatory episodes that affect the skin and peripheral nerves and can develop...
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Sonographic evaluation of peripheral nerve involvement in leprosy with electrophysiologic correlation: a cross-sectional study in sub-Himalayan region
BackgroundLeprosy is an age-old chronic infectious disease with the majority of annual new case detections from South-East Asia. The disease...
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Should prophylaxis against Pneumocystis jirovecii pneumonia be considered in selected patients with leprosy reactions?
Leprosy reactions often require prolonged high-dose steroids or immunosuppressive drugs, putting patients at risk of Pneumocystis jirovecii pneumonia...
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Role of shear wave elastography in treatment follow-up of leprosy neuropathy
PurposeGrayscale ultrasonography when complemented with shear wave elastography helps in better evaluation of treatment response of leprosy...
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An individual randomised efficacy trial of autologous blood products, leukocyte and platelet-rich fibrin (L-PRF), to promote ulcer healing in leprosy in Nepal: the TABLE trial protocol
BackgroundLeprosy is curable with multidrug therapy and treatment in the early stages can prevent disability. However, local nerve damage can lead to...
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A case report and literature review: Mycobacterium leprae infection diagnosed by metagenomic next-generation sequencing of cerebrospinal fluid
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae ( M. leprae ) that is responsible for deformities and irreversible...
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World Health Organization (WHO) antibiotic regimen against other regimens for the treatment of leprosy: a systematic review and meta-analysis
BackgroundTo evaluate the effectiveness and safety of the World Health Organization antibiotic regimen for the treatment of paucibacillary (PB) and...
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Epidemiological, clinical and immune factors that influence the persistence of antiphospholipid antibodies in leprosy
IntroductionAntiphospholipid antibodies (aPL) are described in individuals with leprosy without the clinical features of antiphospholipid antibody...
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Leprosy – eliminated and forgotten: a case report
BackgroundLeprosy is a disease that was declared eliminated in 2010 from Nepal; however, new cases are diagnosed every year. The difficulty arises...
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Neglected tropical rheumatic diseases
The complexities of dealing with rheumatic diseases in tropical countries are diverse and likely due to limited health care infrastructure, lack of...
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Neurosurgical treatment of leprosy neuropathy in a low-incidence, European country
IntroductionLeprosy is nowaday increasingly encountered in non-endemic countries. Nerve involvement is common. Swelling of the nerves may lead to...
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Musculoskeletal involvement in neglected tropical diseases: a comprehensive review
Neglected tropical diseases (NTDs) encompass a group of diseases predominantly found in tropical regions, with origins dating back to their inclusion...
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Infectious eye disease in the 21st century—an overview
Infectious diseases affecting the eye often cause unilateral or asymmetric visual loss in children and people of working age. This group of...
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Epidemics and outbreaks of peripheral nervous system disorders: I. infectious and immune-mediated causes
The history of mankind is marked by numerous epidemics, some of which involved diseases of the peripheral nervous system, either infectious or...
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Ocular vs neurosyphilis. are they the same? A guide to investigation and management
This article reviews key concepts in the epidemiology, clinical features, diagnosis and management of ocular syphilis. It is not a systematic review...
