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Global patterns of rebound to normal RSV dynamics following COVID-19 suppression
BackgroundAnnual epidemics of respiratory syncytial virus (RSV) had consistent timing and intensity between seasons prior to the SARS-CoV-2 pandemic...
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Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice
Long-term memories are believed to be encoded by unique transcriptional signatures in the brain. The expression of immediate early genes (IEG)...
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Artifact suppression for breast specimen imaging in micro CBCT using deep learning
BackgroundCone-beam computed tomography (CBCT) has been introduced for breast-specimen imaging to identify a free resection margin of abnormal...
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A Novel Approach to Fetal ECG Extraction Using Temporal Convolutional Encoder–Decoder Network (TCED-Net)
To extract weak fetal ECG signals from the mixed ECG signal on the mother's abdominal wall, providing a basis for accurately estimating fetal heart...
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Deciphering the acetylation code of p53 in transcription regulation and tumor suppression
Although it is well-established that p53-mediated tumor suppression mainly acts through its ability in transcriptional regulation, the molecular...
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Atomoxetine for suppression of vasovagal syncope
ObjectiveVasovagal syncope (VVS) is a common clinical condition with few effective medical therapies. The study aimed to evaluate the effectiveness...
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Net clinical benefit of DOACs vs. usual anticoagulation treatment in venous thromboembolism and active cancer: systematic review and meta-analysis
AbstractPatients with active cancer are at high risk of recurrent venous thromboembolism (VTE). Usual treatment includes low molecular weight heparin...
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Development of U-Net Breast Density Segmentation Method for Fat-Sat MR Images Using Transfer Learning Based on Non-Fat-Sat Model
To develop a U-net deep learning method for breast tissue segmentation on fat-sat T1-weighted (T1W) MRI using transfer learning (TL) from a model...
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Effect of convergence on the horizontal VOR in normal subjects and patients with peripheral and central vestibulopathy
BackgroundVestibular compensatory eye movements provide visual fixation stabilization during head movement. The anatomic pathways mediating a normal...
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HIV Care Coordination promotes care re-engagement and viral suppression among people who have been out of HIV medical care: an observational effectiveness study using a surveillance-based contemporaneous comparison group
BackgroundMedical care re-engagement is critical to suppressing viral load and preventing HIV transmission, morbidity and mortality, yet few rigorous...
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Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses
The PI3K pathway is one of the most frequently altered signaling pathways in human cancer. In addition to its function in cancer cells, PI3K plays a...
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Examining the effect of synthetic data augmentation in polyp detection and segmentation
PurposeAs with several medical image analysis tasks based on deep learning, gastrointestinal image analysis is plagued with data scarcity, privacy...
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Transgender Women in the Female Category of Sport: Perspectives on Testosterone Suppression and Performance Advantage
Males enjoy physical performance advantages over females within competitive sport. The sex-based segregation into male and female sporting categories...
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RETRACTED ARTICLE: Suppression of NF-κB signaling by ECN in an arthritic model of inflammation
BackgroundThe 7β-(3-ethyl- cis -crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN), a sesquiterpenoid isolated from the Tussilag...
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Engagement in HIV care and viral suppression following changes in long-term opioid therapy for treatment for chronic pain
Chronic pain is common among persons living with HIV and changes in opioid prescribing practices may complicate HIV care management. Using medical...
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Menstrual Cycle Associated Alteration of Vastus Lateralis Motor Unit Function
BackgroundEstrogen and progesterone are the primary female sex hormones and have net excitatory and inhibitory effects, respectively, on neuronal...
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Effect of a high-citrate beverage on urine chemistry in patients with calcium kidney stones
A well-accepted strategy to prevent kidney stones is to increase urine volume by increasing oral intake of fluids, especially water, to lower...
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Prognostic value of soluble suppression of tumorigenesis-2 (sST2) for cardiovascular events in coronary artery disease patients with and without diabetes mellitus
BackgroundSoluble suppression of tumorigenesis-2 (sST2) is implicated in myocardial overload and has long been recognized as an inflammatory marker...
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The effect of hyperoxia on muscle sympathetic nerve activity: a systematic review and meta-analysis
PurposeWe conducted a meta-analysis to determine the effect of hyperoxia on muscle sympathetic nerve activity in healthy individuals and those with...
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The Dunning–Kruger effect: subjective health perceptions on smoking behavior among older Chinese adults
BackgroundThe intrinsic damage and external hazards of smoking are major risk factors for poorer health and are recognized as a global health issue...