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Nerve fibre organisation in the human optic nerve and chiasm: what do we really know?
A recent anatomical study of the human optic chiasm cast doubt on the widespread assumption that nerve fibres travelling in the human optic nerve and...
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The structure–function relationship between multifocal pupil perimetry and retinal nerve fibre layer in glaucoma
BackgroundMultifocal pupillographic objective perimetry (mfPOP) is a novel method for assessing functional change in diseases like glaucoma. Previous...
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In vivo corneal confocal microscopy as a non-invasive test to assess obesity induced small fibre nerve damage and inflammation
PurposeTo investigate small nerve fibre damage and inflammation at the level of the sub-basal nerve plexus (SNP) of severe obese patients and compare...
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Quantification of peripapillary nerve fibre elevation and its association with axial length, optic disc tilt, and parapapillary atrophy area in young, healthy eyes
BackgroundEyes with peripapillary nerve fibre elevation (pNFE) may have a gap between the optic nerve papillary margin on colour fundus photography...
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Corneal stress‒strain index in relation to retinal nerve fibre layer thickness among healthy young adults
Background/ObjectivesTo determine the relationship between corneal stress-strain index (SSI) and retinal nerve fibre layer (RNFL) thickness.
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Quantitative evaluation of dissociated optic nerve fibre layer (DONFL) following idiopathic macular hole surgery
ObjectivesTo quantitatively evaluate concentric macular dark spots (CMDS) on spectral-domain optical coherence tomography (SD-OCT) to determine the...
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Acute Sensory Neuropathy with Small and Large Nerve Fibre Involvement After Vaccination for Influenza Virus: a Rare Sensory Guillain–Barre variant? A Case Report
Guillain-Barré syndrome (GBS) refers to an acute autoimmune peripheral neuropathy spectrum with various subtypes. It is mostly developed by patients...
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Small-Fibre-Neuropathie – eine Übersicht
Small fibre neuropathy (SFN) is an underdiagnosed disorder affecting the small sensory and autonomic nerve fibres and can be diagnosed by the...
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Corneal confocal microscopy identifies corneal nerve loss and increased Langerhans cells in presymptomatic carriers and patients with hereditary transthyretin amyloidosis
BackgroundHereditary transthyretin amyloidosis (ATTRv amyloidosis) is a rare, but life-threatening protein misfolding disorder due to TTR gene...
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Corneal nerve changes in herpes zoster ophthalmicus: a prospective longitudinal in vivo confocal microscopy study
PurposeTo study the changes in corneal nerves and corneal sensitivity over a 6-month period in patients with herpes zoster ophthalmicus (HZO)...
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Glucagon-like peptide-1 receptor agonists reverse nerve morphological abnormalities in diabetic peripheral neuropathy
Aims/hypothesisDiabetic peripheral neuropathy (DPN) is a highly prevalent cause of physical disability. Glucagon-like peptide-1 receptor agonists...
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Structural changes in Schwann cells and nerve fibres in type 1 diabetes: relationship with diabetic polyneuropathy
Aims/hypothesisOur aim was to investigate structural changes of cutaneous Schwann cells (SCs), including nociceptive Schwann cells (nSCs) and axons,...
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Assessment of retinal and choroidal vessel density and nerve fibre layer thickness changes after orbitotomy in patients with severe non-active thyroid orbitopathy: a prospective study
PurposeTo evaluate the optical coherence tomography angiogram changes in non-active severe thyroid-related ophthalmopathy patients after cosmetic...
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Nonregional small fibre neuropathy in cases of autoimmune autonomic neuropathy
ObjectiveAutonomic small fibre neuropathy is described in patients with autoimmune autonomic neuropathy (AAN). Few data are available on...
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Corneal nerve loss and increased Langerhans cells are associated with disease severity in patients with rheumatoid arthritis
Background/ObjectivesRheumatoid arthritis (RA) is a multisystem autoimmune disorder characterized by articular and extra-articular manifestations....
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Effects of dietary fibre on metabolic health and obesity
Obesity and metabolic syndrome represent a growing epidemic worldwide. Body weight is regulated through complex interactions between hormonal, neural...
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Changes in retinal nerve fibre layer, ganglion cell layer and visual function in eyes with thyroid eye disease of different severities with and without orbital decompression
PurposeTo evaluate progressive changes in retinal nerve fibre layer (RNFL), ganglion cell layer/inner plexiform layer (GCL/IPL) and visual function...
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A comparison of macular ganglion cell and retinal nerve fibre layer optical coherence tomographic parameters as predictors of visual outcomes of surgery for pituitary tumours
PurposeThe prognostic value of optical coherence tomography (OCT) of the macular ganglion cell layer (mGGL) versus peripapillary retinal nerve fibre...
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Bariatric surgery leads to an improvement in small nerve fibre damage in subjects with obesity
IntroductionSubjects with obesity have metabolic risk factors for nerve fibre damage. Because bariatric surgery improves these risk factors we have...