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Treatment of Seizures in the Neonate: Special Report From the ILAE Task Force on Neonatal Seizures, 2022
The International League Against Epilepsy (ILAE) task force on neonatal seizures has recently published draft guidelines and consensus-based...
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Neonatal seizures during extra corporeal membrane oxygenation support
To evaluate EEG monitoring during neonatal ECMO and to identify any correlations between seizure detection to abnormal neuroimaging. Eight-year,...
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Neonatal seizures—diagnostic options and treatment recommendations
Seizures in neonates should prompt rapid evaluation to verify the diagnosis, determine etiology, and initiate appropriate treatment. Neonatal seizure...
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Neonatal brain MRI and short-term outcomes after acute provoked seizures
ObjectiveWe investigated how diagnosis and injury location on neonatal brain MRI following onset of acute provoked seizures was associated with short...
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Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures
AbstractThe blooming of neonatal neurocritical care over the last decade reflects substantial advances in neuromonitoring and neuroprotection. The...
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Levetiracetam versus Phenobarbitone for Management of Neonatal Seizures: A Systematic Review and Meta-analysis
ObjectivesTo review whether levetiracetam is non-inferior to phenobarbitone as the first-choice antiseizure medication (ASM).
MethodsThe authors...
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Practical Approaches to the Treatment of Neonatal Seizures
Purpose of reviewThis paper critically reviews the current literature and evidence on diagnosis, classification, clinical approach, and management of...
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Acute symptomatic seizures in newborns: a narrative review
Acute symptomatic seizures are the main sign of neurological dysfunction in newborns. This is linked to the unique characteristics of the neonatal...
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Neonatal Seizures—Perspective in Low-and Middle-Income Countries
Neonatal seizures are the commonest neurological emergency and are associated with poor neurodevelopmental outcome. While they are generally...
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Comparison between Phenobarbitone and Levetiracetam as the initial anticonvulsant in preterm neonatal seizures — a pilot randomized control trial in develo** country setup
This study aimed to compare the efficacy and safety of intravenous Levetiracetam and Phenobarbitone in the treatment of seizures in preterm neonates....
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Seizures after initiation of rewarming in cooled infants with hypoxic ischaemic encephalopathy
BackgroundSeizures after initiation of rewarming from therapeutic hypothermia for neonatal encephalopathy are well recognised but not easy to predict.
...
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Falls in oxygen saturations accompany electrographic seizures in term neonates: an observational study
BackgroundEffective seizure detection is important however, clinical signs of seizure activity may be subtle in neonates. This study aimed to...
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Electrographic monitoring for seizure detection in the neonatal unit: current status and future direction
AbstractNeonatal neurocritical intensive care is dedicated to safeguarding the newborn brain by prioritising clinical practices that promote early...
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Whole-exome sequencing with targeted analysis and epilepsy after acute symptomatic neonatal seizures
BackgroundThe contribution of pathogenic gene variants with development of epilepsy after acute symptomatic neonatal seizures is not known.
...
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Hearing impairment after asphyxia and neonatal encephalopathy: a Norwegian population-based study
The purpose of this study is to evaluate the association between perinatal asphyxia, neonatal encephalopathy, and childhood hearing impairment. This...
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Neuromonitoring in neonatal intensive care units—an important need towards individualized neuroprotective care
Neuromonitoring has been widely accepted as an important part in neonatal care. Amplitude-integrated EEG (aEEG) and near-infrared spectroscopy (NIRS)...
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Impact of gestational diabetes mellitus on neonatal outcomes in small for gestational age infants: a multicenter retrospective study
ObjectiveTo evaluate obstetric and perinatal outcomes among small for gestational age (SGA) infants born to patients diagnosed with Gestational...
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Neonatal outcomes in pregnancies complicated by placenta accreta- a matched cohort study
PurposePregnancies complicated by placenta accreta spectrum (PAS) are associated with severe maternal morbidities. The aim of this study is to...
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New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: II. Treatments in Clinical Development
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) plays an important role in the modulation of neuronal excitability, and a disruption of...