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Effects of Simulated Microgravity on Rat Reproductive System: Potential Benefits of Vitamin D3 Intervention
Gravity in space can have a negative impact on the reproductive system. Given that the reproductive system is one of vitamin D's objectives, this...
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Coadministration of doxorubicin with vitamin D3, Lactobacillus acidophilus, and Lactobacillus casei in the 4T1 mouse model of breast cancer: anticancer and enteroprotective effects
The use of doxorubicin (Dox) in the treatment of breast cancer negatively affects the intestines and other tissues. Many studies have proven that...
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Vitamin D supplementation in primary hyperparathyroidism: effects on 1,25(OH)2 vitamin D and FGF23 levels
PurposeIn patients with Primary Hyperparathyroidism (PHPT) vitamin D deficiency has been associated with more severe presentations. Our aim was to...
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Vitamin D3 Supplementation Effects on Spermatogram and Oxidative Stress Biomarkers in Asthenozoospermia Infertile Men: a Randomized, Triple-Blind, Placebo-Controlled Clinical Trial
The objective is to evaluate the effects of vitamin D3 (VD3) on sperm parameters and seminal and serum oxidative stress (OS) biomarkers in...
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Sunlight Exposure vs Oral Vitamin D Supplementation for Prevention of Vitamin D Deficiency in Infancy: A Randomized Controlled Trial
ObjectiveTo compare the efficacy of sunlight exposure and oral vitamin D3 supplementation to achieve vitamin D sufficiency in infants at 6 months of...
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Vitamin D3 attenuates oxidative stress and regulates glucose level and leukocyte count in a semi-chronic streptozotocin-induced diabetes model
PurposeVitamin D3 (vit-D3) is a potent immunomodulator with anti-inflammatory and antioxidative properties. We used streptozotocin (STZ)-induced rat...
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Supplementation with vitamin D improves the embryo quality in in vitro fertilization (IVF) programs, independently of the patients’ basal vitamin D status
PurposeThe study aims to demonstrate the effects of Vitamin D (VD) supplementation, prior to oocyte pick-up within IVF protocols, in women with...
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Causal association of genetically determined circulating vitamin D metabolites and calcium with multiple sclerosis in participants of European descent
BackgroundVitamin D is an important regulator of calcium. Mendelian randomization (MR) studies exclusively focused on the circulating total...
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Modulation of the vitamin D/vitamin D receptor system in osteoporosis pathogenesis: insights and therapeutic approaches
Osteoporosis is a prevalent bone disorder characterized by low bone mineral density (BMD) and deteriorated bone microarchitecture, leading to an...
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Need for Testing and Supplementation of Vitamin D3 After Release of COVID-19 Lockdown in Patients with Increased Musculoskeletal Pain
AimsTo evaluate vitamin D3 levels in patients who presented with increased musculo-skeletal pain after release of lockdown period when compared to...
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Vitamin D metabolism in cancer: potential feasibility of vitamin D metabolism blocking therapy
In this review, we discuss the possibility of the vitamin D metabolizing enzyme CYP24A1 being a therapeutic target for various tumors including...
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The effect of vitamin D supplementation on attacks in PFAPA syndrome patients with low vitamin D levels
Background-aimTo evaluate the effect of vitamin D supplementation on the frequency and duration of attacks in patients of PFAPA syndrome with low...
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Vitamin D and myopia: a review
Myopia is a worldwide public health problem of vision disorder caused by multiple factors, which has posed a huge socioeconomic burden, raising...
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Optimisation of vitamin D status in global populations
AbstractVitamin D is important for musculoskeletal health. Concentrations of 25-hydroxyvitamin D, the most commonly measured metabolite, vary...
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Evaluation of vitamin D levels and affecting factors of vitamin D deficiency in healthy children 0–18 years old
The frequency of vitamin D deficiency in healthy children is relatively high. Moreover, vitamin D supplementation in children is under the requested...
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The effects of Vitamin D3 supplementation on Spermatogram and endocrine factors in asthenozoospermia infertile men: a randomized, triple blind, placebo-controlled clinical trial
ObjectiveEvaluate the effects of vitamin D3 (VD3) on sperm parameters and endocrine markers in infertile men with asthenozoospermia.
Materials and...
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Long-term effects of vitamin D supplementation and maintaining sufficient vitamin D on knee osteoarthritis over 5 years
ObjectivesThis study aimed to investigate the long-term effect of vitamin D supplementation compared to placebo over 5 years in participants with...
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Vitamin D and human health: evidence from Mendelian randomization studies
We summarized the current evidence on vitamin D and major health outcomes from Mendelian randomization (MR) studies. PubMed and Embase were searched...
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A Prospective Open-Label Dose–Response Study to Correct Vitamin D Deficiency in Cirrhosis
BackgroundPatients with advanced liver disease often have vitamin D deficiency, but the daily dosages of vitamin D 3 needed to raise their serum...
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What is known about the effects of vitamin D in neuropsychiatric lupus?
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect several organs and systems. The central and/or peripheral nervous system...
