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Self-medication with Novel Psychoactive Substances (NPS): a Systematic Review
Currently, novel psychoactive substance (NPS) use presents a challenging issue for authorities. To effectively tackle the use of NPS, a deeper...
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The new neural pressure support (NPS) mode and the helmet: did we find the dynamic duo?
BackgroundNoninvasive ventilation (NIV) is commonly used in clinical practice to reduce intubation times and enhance patient comfort. However,...
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The Correlation between NPS and Polysubstance Use in High-Risk Population: a Five-year Longitudinal Study in Taiwan
The emergence of new synthetic substances (NPS) leads to rapid changes in substance prevalence. Here urine analysis and questionnaires were employed...
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Jug-PLGA-NPs, a New Form of Juglone with Enhanced Efficiency and Reduced Toxicity on Melanoma
ObjectiveTo verrify the anti-tumor efficacy and toxicity between juglone (Jug) and Jug-loaded PLGA nanoparticles (Jug-PLGA-NPs).
Methods ... -
Intoxication by 3-MeO-PCP and O-desmethyltramadol: an unusual NPS mix
Over the past few years, the new psychoactive substances’ phenomenon has been continuously studied. Its dynamic context is characterized by a broad...
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A study on the 10-year trend of surgeries performed for lumbar disc herniation and comparative analysis of prescribed opioid analgesics and hospitalization duration: 2010–2019 HIRA NPS Data
BackgroundThis study, utilizing the claims data from the Health Insurance Review and Assessment Service of Korea, aimed to examine the 10-year...
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Virtual ‘Experiential Expert’ Communities of Practice in Sharing Evidence-Based Prevention of Novel Psychoactive Substance (NPS) Use: the Portuguese Experience
We present findings from a unique virtual community of practice piloted to support a programme of prevention evidence and knowledge sharing among...
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A fluorine turns a medicinal benzodiazepine into NPS: the case of flualprazolam
PurposeThe purpose of this review is to summarize the existing knowledge on flualprazolam, a novel ‘designer’ benzodiazepine that derives from the...
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Patient perspectives on the role of orthopedic nurse practitioners: a cross-sectional study
BackgroundThe inclusion of nurse practitioners (NPs) specializing in orthopedics shows potential for improving the quality of care for orthopedic...
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Biogenic zinc selenide nanoparticles fabricated using Rosmarinus officinalis leaf extract with potential biological activity
Zinc selenide nanoparticles (ZnSe) are semiconductor metals of zinc and selenium. ZnSe NPs are advantageous for biomedical and bio-imaging...
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Fatal intoxication with U-47700 in combination with other NPS (N-ethylhexedrone, adinazolam, 4-CIC, 4-CMC) confirmed by identification and quantification in autopsy specimens and evidences
PurposeWe present a case of fatal intoxication with U-47700 in combination with other NPS ( N -ethylhexedrone, adinazolam, 4-chloro- N -isopropylcathinon...
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Natural products in osteoarthritis treatment: bridging basic research to clinical applications
Osteoarthritis (OA) is the most prevalent degenerative musculoskeletal disease, severely impacting the function of patients and potentially leading...
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Chitosan-encapsulated naringenin promotes ROS mediated through the activation of executioner caspase-3
We previously reported that chitosan nanoparticle-encapsulated Naringenin (CS-NPs/NAR) could scavenge free radicals at lower doses and be cytotoxic...
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Development of chitosan-folate modified PLGA nanoparticles for targeted delivery of diosgenin as an anticancer agent
Diosgenin as a potential phytoconstituent and steroidal saponin manifested significant anticancer agents against various cancers. To enhance its...
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Prognostic value of pre-treatment Naples prognostic score (NPS) in patients with osteosarcoma
BackgroundThis study aimed to evaluate the clinical significance of pre-treatment Naples prognostic score (NPS) in patients with osteosarcoma.
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Genetically programmable cell membrane-camouflaged nanoparticles for targeted combination therapy of colorectal cancer
Cell membrane-camouflaged nanoparticles possess inherent advantages derived from their membrane structure and surface antigens, including prolonged...
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Natural approach of using nisin and its nanoform as food bio-preservatives against methicillin resistant Staphylococcus aureus and E.coli O157:H7 in yoghurt
BackgroundNatural antimicrobial agents such as nisin were used to control the growth of foodborne pathogens in dairy products. The current study...
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Change in number of pain sites - which factors are important? A 12-year prospective cohort study
BackgroundPain in multiple body sites is common and often persistent. The purpose of this prospective study was to examine the change in the number...
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Predictive value of the Naples prognostic score on postoperative delirium in the elderly with gastrointestinal tumors: a retrospective cohort study
BackgroundPostoperative delirium (POD) is a common complication among elderly patients after surgery. The Naples Prognostic Score (NPS), a novel...
