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The effect of nurse practitioner (NP-led) care on health-related quality of life in people with multiple sclerosis – a randomized trial
BackgroundCare for People with Multiple Sclerosis (PwMS) is increasingly complex, requiring innovations in care. Canada has high rates of MS; it is...
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COMMunity of Practice And Safety Support for Navigating Pain (COMPASS-NP): study protocol for a randomized controlled trial with home care workers
BackgroundChronic pain is a prevalent and costly problem that often has occupational origins. Home care workers (HCWs) are at high risk for...
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Pharmacokinetics and Biochemical Efficacy of an α1-Proteinase Inhibitor (Aralast NP) in α1-Antitrypsin Deficiency: a Cross-Product Retrospective Comparability Analysis
IntroductionAugmentation therapy with plasma-derived α 1 -proteinase inhibitor (A1PI) products is currently the only approved disease-specific therapy...
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Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial
BackgroundThe pivotal ASPECT-NP trial showed ceftolozane/tazobactam was non-inferior to meropenem for the treatment of ventilated...
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Outcomes in participants with failure of initial antibacterial therapy for hospital-acquired/ventilator-associated bacterial pneumonia prior to enrollment in the randomized, controlled phase 3 ASPECT-NP trial of ceftolozane/tazobactam versus meropenem
BackgroundCeftolozane/tazobactam, a combination antibacterial agent comprising an anti-pseudomonal cephalosporin and β-lactamase inhibitor, is...
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Rydberg energies and transition probabilities of Li I for np–ms (m ≤ 5) transitions
BackgroundMathematical modeling provides grounds for understanding scientific systems theoretically. It serves as a guide for experimentalists in...
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Measuring the effects of nurse practitioner (NP)-led care on depression and anxiety levels in people with multiple sclerosis: a study protocol for a randomized controlled trial
BackgroundCanada has one of the highest rates of multiple sclerosis (MS) in the world. Treatments and supports for people with MS (PwMS) have become...
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Ceftolozane/tazobactam probability of target attainment and outcomes in participants with augmented renal clearance from the randomized phase 3 ASPECT-NP trial
BackgroundThe randomized, double-blind, phase 3 ASPECT-NP trial evaluated the efficacy of 3 g of ceftolozane/tazobactam (C/T) versus 1 g of meropenem...
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Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial
BackgroundCeftolozane/tazobactam is approved for treatment of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) at double the...
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The ceramide [NP]/[NS] ratio in the stratum corneum is a potential marker for skin properties and epidermal differentiation
BackgroundSpecific species of ceramides (Cer), major constituents of lipids in the stratum corneum (SC), are decreased and are correlated with SC...
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Healthcare Resource Utilization of Ceftolozane/Tazobactam Versus Meropenem for Ventilated Nosocomial Pneumonia from the Randomized, Controlled, Double-Blind ASPECT-NP Trial
IntroductionHospital-acquired and ventilator-associated bacterial pneumonia (HABP and VABP) are associated with significant healthcare resource...
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Cross cultural adaptation and validation of burn specific health scale- brief in Nepali (BSHS-B-Np)
BackgroundBurns are a global health problem affecting the survivors and disrupting many aspects of their lives. It is the second most common injury...
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Orthopedics for Physician Assistant and Nurse Practitioner Students An Introductory Guide
This practical introductory guide provides PA/NP students with the tools to recognize and begin treatment of the most common orthopedic problems, to...
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Real-Life Response to Biologics in Severe Asthma with Nasal Polyposis: Insights from the Belgian Severe Asthma Registry
BackgroundNasal polyposis (NP) is a comorbidity of type 2 severe asthma (SA) which could influence response to SA biologics.
MethodsWe evaluated...
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Magnetic Resonance Imaging-Negative Cerebral Amyloid Angiopathy: Cerebrospinal Fluid Amyloid-β42 over Amyloid Positron Emission Tomography
BackgroundCerebral amyloid angiopathy (CAA) pathology is becoming increasingly important in Alzheimer’s disease (AD) because of its potential link to...
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The optimal ratio of endoscope-sheath diameter with negative-pressure ureteral access sheath: an in vitro research
PurposeTo maintain safe intrarenal pelvic pressure (IPP), the combination of flexible ureteroscope (fURS) and traditional ureteral access sheath...
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Submucosal Trans-Septal Suturing Technique After a Septal Extension Graft with Porous High-Density Polyethylene: A Technical Report
BackgroundPorous high-density polyethylene (pHDPE) is an alternative material for a septal extension graft (SEG) in oriental rhinoplasty when...
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Short- and long-term post-nephrectomy outcomes for retroperitoneal liposarcoma from a high-volume sarcoma center: a propensity score matching analysis
BackgroundMultivisceral en bloc resection with the ipsilateral kidney is commonly performed in patients with retroperitoneal liposarcoma (RLPS). We...
