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Reduction of N-acetyl aspartate (NAA) in association with relapse in early-stage psychosis: a 7-Tesla MRS study
Understanding the biological underpinning of relapse could improve the outcomes of patients with psychosis. Relapse is elicited by multiple...
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Evaluation of the diagnostic utility on 1.5T and 3.0T 1H magnetic resonance spectroscopy for temporal lobe epilepsy
Background1 H magnetic resonance spectroscopy ( 1 H-MRS) can be used to study neurological disorders because it can be utilized to examine the...
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Neurometabolite levels in the brains of patients with autism spectrum disorders: A meta-analysis of proton magnetic resonance spectroscopy studies (N = 1501)
Evidence suggests that neurometabolite alterations may be involved in the pathophysiology of autism spectrum disorders (ASDs). We performed a...
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Post-chemo-radiotherapy response and pseudo-progression evaluation on glioma cell types by multi-parametric magnetic resonance imaging: a prospective study
BackgroundWe focused on Differentiated pseudoprogression (PPN) of progression (PN) and the response to radiotherapy (RT) or chemoradiotherapy (CRT)...
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Could thalamic biochemical changes correlate to cognitive impairment in idiopathic generalized epilepsy?
BackgroundThe thalamus is crucial in the development of idiopathic generalized epilepsy (IGE), which could lead to cognitive dysfunctions, according...
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Adaptive Growth of the Ductus Arteriosus and Aortic Isthmus in Various Ductus-Dependent Complex Congenital Heart Diseases
BackgroundThe ductus arteriosus (DA) is critical in maintaining postnatal circulation in neonates with obstructed systemic circulation (OSC) and...
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Metabolic changes assessed by 1H MR spectroscopy in the corpus callosum of post-COVID patients
ObjectiveMany patients with long COVID experience neurological and psychological symptoms. Signal abnormalities on MR images in the corpus callosum...
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Simultaneous high-resolution whole-brain MR spectroscopy and [18F]FDG PET for temporal lobe epilepsy
PurposePrecise lateralizing the epileptogenic zone in patients with drug-resistant mesial temporal lobe epilepsy (mTLE) remains challenging,...
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High-grade glioma and solitary metastasis: differentiation by spectroscopy and advanced magnetic resonance techniques
BackgroundThe differentiation by means of magnetic resonance between high-grade gliomas and intracranial solitary single metastasis is of the utmost...
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Predicting TERT promoter mutation status using 1H-MR spectroscopy and stretched-exponential model of diffusion-weighted imaging in IDH-wildtype diffuse astrocytic glioma without intense enhancement
PurposeIsocitrate dehydrogenase (IDH )-wildtype diffuse astrocytic glioma with telomerase reverse transcriptase ( TERT ) promoter mutation is defined...
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Metabolite changes in the posterior cingulate cortex could be a signature for early detection of Alzheimer’s disease: a systematic review and meta-analysis study based on 1H-NMR
BackgroundPosterior cingulate cortex (PCC) is a paralimbic cortical structure with a fundamental role in integrative functions of the default mode...
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Neurometabolic changes in neonates with congenital heart defects and their relation to neurodevelopmental outcome
BackgroundAltered neurometabolite ratios in neonates undergoing cardiac surgery for congenital heart defects (CHD) may serve as a biomarker for...
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Neuropsychiatric manifestations and magnetic resonance spectroscopy of the brain in systemic lupus erythematosus patients
BackgroundNeuropsychiatric manifestations of lupus (NPSLE) are considered one of the major and most devastating lupus manifestations. The aim of this...
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Differentiating multiple sclerosis from cerebral small vessel disease using diffusion tensor imaging and magnetic resonance spectroscopy on normally appearing thalami
BackgroundDiffusion tensor imaging (DTI) and magnetic resonance spectroscopy (1H-MRS) can detect the microstructural changes in normal-appearing...
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Early assessment of injury with optical markers in a piglet model of neonatal encephalopathy
BackgroundOpportunities for adjunct therapies with cooling in neonatal encephalopathy are imminent; however, robust biomarkers of early assessment...
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Usefulness of combined diffusion tensor imaging, arterial spin labelling and spectroscopic interictal analysis in refractory epilepsy
BackgroundEpilepsy is a common neurological disorder especially in pediatric population. Patients with non-lesional epilepsy have normal conventional...
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The full spectrum of MRI findings in 18 patients with Canavan disease: new insights into the areas of selective susceptibility
IntroductionCanavan disease (CD) is a rare autosomal recessive neurodegenerative disorder caused by a deficiency of aspartoacylase A, an enzyme that...
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Umbrella review and network meta-analysis of diagnostic imaging test accuracy studies in differentiating between brain tumor progression versus pseudoprogression and radionecrosis
PurposeIn this study we gathered and analyzed the available evidence regarding 17 different imaging modalities and performed network meta-analysis to...
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Microstructural and Metabolic Changes in Normal Aging Human Brain Studied with Combined Whole-Brain MR Spectroscopic Imaging and Quantitative MR Imaging
PurposeThis study aimed to detect age-related brain metabolic and microstructural changes in healthy human brains by the use of whole-brain proton...
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Dynamics of γ-aminobutyric acid concentration in the human brain in response to short visual stimulation
ObjectiveTo find a possible quantitative relation between activation-induced fast (< 10 s) changes in the γ-aminobutyric acid (GABA) level and the...
