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Impact of cardiac history and myocardial scar on increase of myocardial perfusion after revascularization
PurposeWe sought to assess the impact of coronary revascularization on myocardial perfusion and fractional flow reserve (FFR) in patients without a...
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Radiomics and deep learning for myocardial scar screening in hypertrophic cardiomyopathy
BackgroundMyocardial scar burden quantified using late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR), has important prognostic...
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Assessment of resting myocardial blood flow in regions of known transmural scar to confirm accuracy and precision of 3D cardiac positron emission tomography
BackgroundComposite invasive and non-invasive data consistently demonstrate that resting myocardial blood flow (rMBF) in regions of known transmural...
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Quality assessment of cardiac magnetic resonance myocardial scar imaging prior to ventricular arrhythmia ablation
High-resolution scar characterization using late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR) is useful for guiding...
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Pulse-Cancellation Echocardiography for Clinical Evaluation of Myocardial Scar Burden
Purpose of ReviewEchocardiography has been completely abandoned as far as myocardial tissue characterization is concerned, but recently, the...
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The scar: the wind in the perfect storm—insights into the mysterious living tissue originating ventricular arrhythmias
BackgroundArrhythmic death is very common among patients with structural heart disease, and it is estimated that in European countries, 1 per 1000...
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Molecular mechanisms of uterine incision healing and scar formation
Wound healing is a tandem process involving inflammation, proliferation, and remodeling, through which damage is repaired and ultimately scar tissue...
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Preventive substrate ablation in chronic post-myocardial infarction patients with high-risk scar characteristics for ventricular arrhythmias: rationale and design of PREVENT-VT study
BackgroundRecent studies showed that an early strategy for ventricular tachycardia (VT) ablation resulted in reduction of VT episodes or mortality....
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Reduced hematopoietic-inflammatory response and worse outcomes in patients with recurrent myocardial infarction in comparison with primary myocardial infarction
BackgroundRecurrent myocardial infarction (RMI) portends an unfavorable outcome, which might be related to diminished hematopoietic-inflammatory...
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Long-term impact of myocardial inflammation on quantitative myocardial perfusion—a descriptive PET/MR myocarditis study
PurposeWhether myocardial inflammation causes long-term sequelae potentially affecting myocardial blood flow (MBF) is unknown. We aimed to assess the...
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Segmental strain for scar detection in acute myocardial infarcts and in follow-up exams using non-contrast CMR cine sequences
BackgroundThe purpose of the study was to investigate feasibility of infarct detection in segmental strain derived from non-contrast cardiac magnetic...
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Late gadolinium enhancement entropy as a new measure of myocardial tissue heterogeneity for prediction of adverse cardiac events in patients with hypertrophic cardiomyopathy
ObjectivesEntropy is a new late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR)–derived parameter that is independent of signal intensity...
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Characterizing the immune response to myocardial infarction in pigs
Though myocardial infarction (MI) in pigs is a well-established translational large animal model, it has not yet been widely used for immunotherapy...
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The Role of Regulatory T Cells in Heart Repair After Myocardial Infarction
Myocardial infarction (MI) remains one of the leading causes of death worldwide. Inflammation and immune responses after MI are of significance to...
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Myocardial tissue changes detected by cardiac MRI in a patient with suspected systemic sarcoidosis
BackgroundThe role of cardiac magnetic resonance imaging in the early management of chronic cardiac inflammatory conditions is growing. Our case...
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Additive effect of admission hyperglycemia on left ventricular stiffness in patients following acute myocardial infarction verified by CMR tissue tracking
BackgroundStress hyperglycemia occurs frequently in patients following acute myocardial infarction (AMI) and may aggravate myocardial stiffness, but...
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Quantitating myocardial fibrosis using extracellular extravascular volume determined from computed tomography myocardial perfusion imaging
PurposeBoth of extracellular extravascular volume (EEV) and extracellular volume fraction (ECV) were proposed to quantify enlargement of myocardial...
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Macrophages in cardiac remodelling after myocardial infarction
Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most prevalent cause of morbidity and mortality among all...
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Ablation targets of scar-related ventricular tachycardia identified by dynamic functional substrate map**
BackgroundDynamic functional substrate map** of scar-related ventricular tachycardia offers better identification of ablation targets with limited...
