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Differentiation of acute non-ST elevation myocardial infarction and acute infarct-like myocarditis by visual pattern analysis: a head-to-head comparison of different cardiac MR techniques
ObjectivesParametric cardiac magnetic resonance (CMR) techniques have improved the diagnosis of pathologies. However, the primary tool for...
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Early surgical outcomes of a modified infarct exclusion technique in acute post-myocardial infarction ventricular septal rupture: a single-centre experience
IntroductionOperative mortality in an acute post-myocardial infarction (AMI) ventricular septal rupture (VSR) is high. In addition to ventricular...
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The Infarct-Limiting Effect of Remote Ischemic Conditioning in Rats Is Not Affected by Aspirin
PurposeRemote ischemic conditioning (RIC) has been shown to be a powerful cardioprotective therapy in animal models. However, a protective effect in...
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No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs
Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major...
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Second-generation extracellular matrix patch for epicardial infarct repair
Current myocardial infarction treatments focus on improving hemodynamics rather than addressing the problem of lost myocardium impairing left...
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PET Imaging of Post-infarct Myocardial Inflammation
Purpose of ReviewTo examine the use of positron emission tomography (PET) for imaging post-infarct myocardial inflammation and repair.
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Aloperine Alleviates Myocardial Injury Induced by Myocardial Ischemia and Reperfusion by Activating the ERK1/2/β-catenin Signaling Pathway
ObjectiveMyocardial ischemia/reperfusion (I/R) injury can cause severe cardiac damage. Aloperine is a quinolizidine alkaloid found in the leaves and...
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Matrix Metalloproteinase-Targeted SPECT/CT Imaging for Evaluation of Therapeutic Hydrogels for the Early Modulation of Post-Infarct Myocardial Remodeling
Following myocardial infarction (MI), maladaptive upregulation of matrix metalloproteinase (MMP) alters extracellular matrix leading to cardiac...
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Osteopontin promotes infarct repair
Understanding how macrophages promote myocardial repair can help create new therapies for infarct repair. We aimed to determine what mechanisms...
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Association of changes in the infarct and remote zone myocardial tissue with cardiac remodeling after myocardial infarction: a T1 and T2 map** study
Tissue structure in the infarct and remote zone myocardium post-acute myocardial infarction (MI) may offer prognostic information concerning left...
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Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry
BackgroundThe inflammatory response occurring in acute myocardial infarction (AMI) has been proposed as a potential pharmacological target....
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Prognostic value of infarct-related-lead Tpeak–Tend/QT ratio in patients with ST-segment elevation myocardial infarction
Tpeak–Tend/QT ratio (Tp–e/QT) in patients with ST-segment elevation myocardial infarction (STEMI) is reportedly associated with major adverse cardiac...
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Comparing the findings and diagnostic sensitivity of cardiovascular magnetic resonance in biopsy confirmed acute myocarditis with infarct-like vs. heart failure presentation
BackgroundCardiovascular magnetic resonance (CMR) is considered the reference imaging modality in providing a non-invasive diagnosis of acute...
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Lysophosphatidic acid contributes to myocardial ischemia/reperfusion injury by activating TRPV1 in spinal cord
Lysophosphatidic acid (LPA) is a bioactive phospholipid that plays a crucial role in cardiovascular diseases. Here, we question whether LPA...
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Effects of OP2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model
PurposeThe present study was to determine whether OP2113 could limit myocardial infarction size and the no-reflow phenomenon in a rat myocardial...
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Myocardial glucose suppression may interfere with the detection of inflammatory cells with FDG-PET as suggested in a canine model of myocardial infarction
BackgroundAfter myocardial infarction, fibrosis and an ongoing dysregulated inflammatory response have been shown to lead to adverse cardiac...
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Lingbao Huxin Pill Alleviates Apoptosis and Inflammation at Infarct Border Zone through SIRT1-Mediated FOXO1 and NF- κ B Pathways in Rat Model of Acute Myocardial Infarction
ObjectiveTo investigate whether Lingbao Huxin Pill (LBHX) protects against acute myocardial infarction (AMI) at the infarct border zone (IBZ) of...
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Spinal cord astrocytes regulate myocardial ischemia–reperfusion injury
Astrocytes play a key role in the response to injury and noxious stimuli, but its role in myocardial ischemia–reperfusion (I/R) injury remains...
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Cardiac magnetic resonance for the early prediction of reverse left ventricular remodeling in patients with ST-segment elevation myocardial infarction
ObjectivesTo evaluate the changes in cardiac magnetic resonance (CMR) characteristics and investigate the predictors of reverse left ventricular...
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Sodium–glucose cotransporter 2 inhibitors reduce myocardial infarct size in preclinical animal models of myocardial ischaemia–reperfusion injury: a meta-analysis
Aims/hypothesisLarge cardiovascular outcome trials demonstrated that the cardioprotective effects of sodium–glucose cotransporter 2 (SGLT2)...
