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Speckle-tracking echocardiography for predicting improvement of myocardial contractile function after revascularization: a meta-analysis of prospective trials
Some studies have indicated that the use of 2D-Speckle tracking echocardiography (2DSTE) aids in predicting recovery of myocardial contractile...
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Myocardial Transit Time Map** by CMR: A Novel Indicator of Microcirculatory Dysfunction in Cardiac Amyloidosis
Cardiac amyloidosis (CA) is characterized by the deposition of amyloid fibrils within the myocardium, resulting in a restrictive physiology. Although...
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Myocardial work across different etiologies of right ventricular dysfunction and healthy controls
Evaluating right ventricular (RV) function remains a challenge. Recently, novel echocardiographic assessment of RV myocardial work (RVMW) by...
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Myocardial Perfusion SPECT Imaging Radiomic Features and Machine Learning Algorithms for Cardiac Contractile Pattern Recognition
A U-shaped contraction pattern was shown to be associated with a better Cardiac resynchronization therapy (CRT) response. The main goal of this study...
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Non-transmural myocardial infarction associated with regional contractile function is an independent predictor of positive outcome: an integrated approach to myocardial viability
BackgroundCardiovascular magnetic resonance permits assessment of irreversible myocardial fibrosis and contractile function in patients with previous...
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Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction
Despite prompt epicardial recanalization in patients presenting with ST-segment elevation myocardial infarction (STEMI), coronary microvascular...
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Role of CMR feature-tracking derived left ventricular strain in predicting myocardial iron overload and assessing myocardial contractile dysfunction in patients with thalassemia major
ObjectiveMyocardial iron overload (MIO) in thalassemia major (TM) may cause subclinical left ventricular (LV) dysfunction which manifests with...
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Computational Analysis of Cardiac Contractile Function
Purpose of ReviewHeart failure results in the high incidence and mortality all over the world. Mechanical properties of myocardium are critical...
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Two-dimensional speckle tracking echocardiography in assessing the subclinical myocardial dysfunction in patients with gestational diabetes mellitus
BackgroundGestational diabetes mellitus (GDM) may increase the risk of cardiovascular disease and accompany asymptomatic deterioration of the...
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Chagas Cardiomyopathy and Myocardial Sympathetic Denervation
Purpose of ReviewMore than a century since its discovery, the pathogenesis of Chagas heart disease (CHD) remains incompletely understood. The role of...
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Extracellular stiffness induces contractile dysfunction in adult cardiomyocytes via cell-autonomous and microtubule-dependent mechanisms
The mechanical environment of the myocardium has a potent effect on cardiomyocyte form and function, yet an understanding of the cardiomyocyte...
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Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission and Ca2+ homeostasis in a murine model of HFpEF
Heart failure with preserved ejection fraction (HFpEF) displays normal or near-normal left ventricular ejection fraction, diastolic dysfunction,...
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Myocardial Metabolism in Heart Failure
Purpose of ReviewMyocardial metabolism is intricately linked to cardiac function. Perturbations of cardiac energy metabolism result in an...
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Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice
Recent studies have demonstrated that hyperglycemia is a major risk factor for the development and exacerbation of cardiovascular disease (CVD)....
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Molecular mechanisms of endothelial dysfunction in coronary microcirculation dysfunction
Coronary microvascular endothelial cells (CMECs) react to changes in coronary blood flow and myocardial metabolites and regulate coronary blood flow...
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Matrix metalloproteinase-2 proteolyzes mitofusin-2 and impairs mitochondrial function during myocardial ischemia–reperfusion injury
During myocardial ischemia and reperfusion (IR) injury matrix metalloproteinase-2 (MMP-2) is rapidly activated in response to oxidative stress. MMP-2...
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Current Role of Myocardial Viability Imaging Using Positron Emission Tomography in Patients with Chronic Ischemic Heart Failure and Left Ventricular Dysfunction
Purpose of ReviewIt is currently debated what role cardiac viability imaging plays in clinical practice, as newer randomized studies have refuted the...
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Role of Myocardial Strain Imaging in Cancer Therapy–Related Cardiac Dysfunction
Purpose of ReviewThis review aims to provide a contemporary perspective on the role of myocardial strain imaging in the management of patients on...
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Obesity in pregnancy is a predictor of persistent subclinical myocardial dysfunction over postpartum period
PurposeNo previous study provided a complete functional evaluation of all cardiac chambers in pregnant women with obesity. Moreover, the impact of...
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Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice
ObjectiveThe SGLT2 inhibitor, canagliflozin, not only reduces glycemia in patients with type 2 diabetes but also exerts cardioprotective effects in...
