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Personal exposure to ultrafine particles in multiple microenvironments among adolescents
BackgroundExperimental studies suggest ultrafine particles (UFPs), the smallest size fraction of particulate matter, may be more toxic than larger...
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Prenatal exposure to multiple environmental chemicals and birth size
BackgroundEpidemiological studies addressing the combined effects of exposure to chemical mixtures at different stages of pregnancy on birth size are...
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In-utero exposure to multiple air pollutants and childhood undernutrition in India
BackgroundSeveral studies have been conducted to understand the impact of socioeconomic and maternal factors on child undernutrition. However,...
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Population Pharmacokinetics and Exposure–Response with Teclistamab in Patients With Relapsed/Refractory Multiple Myeloma: Results From MajesTEC-1
BackgroundTeclistamab, a B-cell maturation antigen × CD3 bispecific antibody, is approved in patients with relapsed/refractory multiple myeloma...
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Effect of prior lenalidomide or daratumumab exposure on hematopoietic stem cell collection and reconstitution in multiple myeloma
BackgroundThe roles of Lenalidomide (Len) and Daratumumab (Dara) in multiple myeloma treatment are well-established, yet their influences on...
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Should multiple imputation be stratified by exposure group when estimating causal effects via outcome regression in observational studies?
BackgroundDespite recent advances in causal inference methods, outcome regression remains the most widely used approach for estimating causal effects...
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Characterization of multiple pesticide exposure in pregnant women in Brittany, France
BackgroundFrance is one of the biggest users of pesticides in Europe and exposure to pesticides is a current concern, especially when it occurs early...
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The Association of Agent Orange Exposure with the progression of monoclonal gammopathy of undetermined significance to multiple myeloma: a population-based study of Vietnam War Era Veterans
Herbicide and pesticide exposure [e.g., agent orange (AO)] is associated with an increased risk of multiple myeloma (MM) due to the contaminant,...
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Ocrelizumab exposure in relapsing–remitting multiple sclerosis: 10-year analysis of the phase 2 randomized clinical trial and its extension
Open-label extension (OLE) studies help inform long-term safety and efficacy of disease-modifying therapies in multiple sclerosis (MS). We report...
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Longitudinal Exposure—Response Modeling of Multiple Indicators of Alzheimer’s Disease Progression
BackgroundProgression in Alzheimer’s disease manifests as changes in multiple biomarker, cognitive, and functional endpoints. Disease progression...
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Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study
BackgroundFetal radiation exposure in pregnant women with trauma is a concern. The purpose of this study was to evaluate fetal radiation exposure...
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Exploring and mitigating potential bias when genetic instrumental variables are associated with multiple non-exposure traits in Mendelian randomization
With the increasing size and number of genome-wide association studies, individual single nucleotide polymorphisms are increasingly found to...
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Performance of Multiple Adherence Measures for pre-exposure Prophylaxis (PrEP) Among Young Women in Kenya
Understanding PrEP adherence is key in the formulation of HIV prevention strategies; however, measurement of adherence can be challenging. We...
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Analysis of Pregnancy Outcomes Following Exposure to Intramuscular Interferon Beta-1a: The AVONEX® Pregnancy Exposure Registry
Background and ObjectivesThere is a lack of well-controlled US studies of intramuscular (IM) interferon beta (IFNβ)-1a use in pregnant women with...
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Evaluation of multiple data sources for predicting increased need for HIV prevention among cisgender women: understanding missed opportunities for Pre-exposure Prophylaxis (PrEP)
BackgroundCiswomen constitute a disproportionately low percentage of pre-exposure prophylaxis for HIV prevention (PrEP) users compared to men....
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A Review of Causal Inference Methods for Estimating the Effects of Exposure Change when Incident Exposure Is Unobservable
Purpose of ReviewResearch questions on exposure change and health outcomes are both relevant to clinical and policy decision making for public...
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Assessing exposure to outdoor advertisement for products high in fat, salt and sugar (HFSS); is self-reported exposure a useful exposure metric?
BackgroundExposure to advertising of unhealthy commodities such as fast-food and gambling is recognised as a risk factor for develo**...
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Prenatal phthalate exposure and fetal penile length and width
BackgroundPhthalates are endocrine-disrupting chemicals with anti-androgenic qualities and studies reported associations between prenatal phthalate...
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Understanding the multidimensional neurodevelopmental outcomes in children after congenital Zika virus exposure
AbstractSince 2016, international research groups have focused on assessing outcomes of children with in utero Zika virus (ZIKV) exposure. While the...
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Exploring Models of Exposure to Primary Care Careers in Training: a Narrative Review
Multiple models of clinical exposure to primary care exist within undergraduate medical education (UME) and graduate medical education (GME). In this...