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A complex case study: coexistence of multi-drug-resistant pulmonary tuberculosis, HBV-related liver failure, and disseminated cryptococcal infection in an AIDS patient
BackgroundHepatitis B virus (HBV) infection can cause liver failure, while individuals with Acquired Immunodeficiency Virus Disease (AIDS) are highly...
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Prevalence and factors associated with reported adverse-events among patients on multi-drug-resistant tuberculosis treatment in two referral hospitals in Uganda
BackgroundMulti-drug-resistant tuberculosis (MDR-TB) treatment involves toxic drugs that cause adverse events (AEs), which are life-threatening and...
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Pediatric multi-drug-resistant tuberculosis in Germany – diagnostic and therapeutic challenges of an “orphan disease”
Delay in diagnosing multidrug-resistant tuberculosis (MDR-pTB) in children prolongs time to effective treatment. Data on risk factors for pediatric...
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Community-based directly observed therapy is effective and results in better treatment outcomes for patients with multi-drug resistant tuberculosis in Uganda
BackgroundHealth facility-based directly observed therapy (HF DOT) is the main strategy for the management of patients with drug-resistant...
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Develo** a patient-centered community-based model for management of multi-drug resistant tuberculosis in Uganda: a discrete choice experiment
BackgroundThe advent of all-oral regimens for the management of multi-drug resistant tuberculosis (MDR-TB) makes the implementation of...
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Efficacy of integrating short-course chemotherapy with Chinese herbs to treat multi-drug resistant pulmonary tuberculosis in China: a study protocol
BackgroundTuberculosis (TB) caused Mycobacterium tuberculosis ( M.tb ) is one of infectious disease that lead a large number of morbidity and...
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Pulmonary tuberculosis case notification and burden of drug resistance among children under 15 years of age in Ethiopia: sub-analysis from third-round drug resistance tuberculosis survey
IntroductionData on the burden of bacteriologically confirmed childhood Tuberculosis (PTB) and drug-resistant TB in Ethiopia is limited due to...
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Determinants of catastrophic costs among households affected by multi-drug resistant tuberculosis in Ho Chi Minh City, Viet Nam: a prospective cohort study
BackgroundGlobally, most people with multidrug-resistant tuberculosis (MDR-TB) and their households experience catastrophic costs of illness,...
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Global prevalence of drug-resistant tuberculosis: a systematic review and meta-analysis
BackgroundTuberculosis is a bacterial infectious disease, which affects different parts of a human body, mainly lungs and can lead to the patient’s...
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Multi-Drug Resistant and Extensively-Drug Resistant Tuberculosis
India is one of the high burden countries for tuberculosis (TB) including multi-drug resistant TB (MDR-TB) and extensively-drug resistant (XDR) TB....
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Medicinal plant Miconia albicans synergizes with ampicillin and ciprofloxacin against multi-drug resistant Acinetobacter baumannii and Staphylococcus aureus
BackgroundGiven the rising occurrence of antibiotic resistance due to the existence and ongoing development of resistant bacteria and phenotypes, the...
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Case Report: Subfertility and Pregnancy Loss due to Genital Tuberculosis
Tuberculosis (TB) is a disease that primarily affects low and middle income countries (LMICs) but is becoming more relevant in Western countries due...
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Factors associated with tuberculosis treatment adherence among tuberculosis patients in the Kumasi metropolis in the Ashanti Region of Ghana; A cross-sectional study
AimAdherence to tuberculosis (TB) treatment options remain critical in achieving positive treatment outcomes and prevent the growing rates of...
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Trend of pulmonary tuberculosis and rifampicin-resistance among tuberculosis presumptive patients in Central Tigray, Ethiopia; 2018 -2023: a six-year retrospective study
BackgroundTuberculosis (TB) is a major public health concern in the develo** countries. Moreover, the emergence of multidrug-resistant tuberculosis...
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Risk factors for mortality among patients diagnosed with multi-drug resistant tuberculosis in Uganda- a case-control study
BackgroundThe World Health Organization (WHO) End TB strategy aims to reduce mortality due to tuberculosis (TB) to less than 5% by 2035. However,...
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Evaluating newly approved drugs in combination regimens for multidrug-resistant tuberculosis with fluoroquinolone resistance (endTB-Q): study protocol for a multi-country randomized controlled trial
BackgroundTreatment for fluoroquinolone-resistant multidrug-resistant/rifampicin-resistant tuberculosis (pre-XDR TB) often lasts longer than...
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The clinical profile and outcomes of drug resistant tuberculosis in Central Province of Zambia
BackgroundThe emergence of Drug Resistant Tuberculosis (DR-TB) is one of the main public health and economic problems facing the world today. DR-TB...
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Distribution patterns of drug resistance Mycobacterium tuberculosis among HIV negative and positive tuberculosis patients in Western Kenya
IntroductionGlobally anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. Kenya is...
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Early detection of tuberculosis: a systematic review
Tuberculosis remains a significant global health challenge. Tuberculosis affects millions of individuals worldwide. Early detection of tuberculosis...
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Silicosis as a predictor of tuberculosis mortality and treatment failure and need for incorporation in differentiated TB care models in India
BackgroundDifferentiated tuberculosis (TB) care is an approach to improve treatment outcomes by tailoring TB management to the particular needs of...
