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Wearable sensor-based quantitative gait analysis in Parkinson’s disease patients with different motor subtypes
Gait impairments are among the most common and disabling symptoms of Parkinson’s disease and worsen as the disease progresses. Early detection and...
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Abnormal cerebellum connectivity patterns related to motor subtypes of Parkinson’s disease
Cerebellar dysfunction may substantially contribute to the clinical symptoms of Parkinson’s disease (PD). The role of cerebellar subregions in...
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Co-occurrence and metabolic biomarkers of sensory and motor subtypes of peripheral neuropathy from paclitaxel
PurposeChemotherapy-induced peripheral neuropathy (CIPN) is the major treatment-limiting toxicity of paclitaxel, which predominantly presents as...
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Olfactory dysfunction and striatal dopamine transporter binding in motor subtypes of Parkinson’s disease
BackgroundOlfactory dysfunction is one of the earliest non-motor symptoms (NMS) in Parkinson’s disease (PD). There are contradictory results...
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Distribution of delirium motor subtypes in the intensive care unit: a systematic sco** review
BackgroundDelirium is the most common cerebral dysfunction in the intensive care unit (ICU) and can be subdivided into a hypoactive, hyperactive, or...
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Gurka vs Slaughter equations to estimate the fat percentage in children with cerebral palsy from all subtypes and levels of the Gross Motor Function Classification System
BackgroundBody composition assessment in children with cerebral palsy (CP) is a challenge, specially the fat percentage. There are different methods...
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An interactive web application to identify early Parkinsonian non-tremor-dominant subtypes
BackgroundParkinson’s disease (PD) patients with tremor-dominant (TD) and non-tremor-dominant (NTD) subtypes exhibit heterogeneity. Rapid...
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Changes in motor activity level in individuals with frontotemporal dementia
Changes in motor activity are common in individuals with Frontotemporal dementia (FTD). Yet, it remains unclear why some individuals become...
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Cerebral palsy in children: subtypes, motor function and associated impairments in Addis Ababa, Ethiopia
BackgroundAlthough, there is no population-level data in Ethiopia, a previous retrospective hospital-based study identified CP as the most common...
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Exploring subtypes of multiple sclerosis through unsupervised machine learning of automated fiber quantification
PurposeThis study aimed to subtype multiple sclerosis (MS) patients using unsupervised machine learning on white matter (WM) fiber tracts and...
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Estimating motor progression trajectory pursuant to temporal dynamic status of cardiac denervation in Parkinson’s disease
BackgroundParkinson’s disease (PD) is a multifaceted disease that encompasses diverse clinical phenotypes. The diversity of PD could be subtyped...
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Association between autonomic dysfunction with motor and non-motor symptoms in patients with Parkinson's disease
To investigate the association between autonomic dysfunction (AutD) and motor as well as non-motor symptoms (NMS) in patients with Parkinson's...
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Nonmotor symptoms and quality of life in Parkinson’s disease with different motor subtypes
ObjectiveTo explore the differences in the features and impact on quality of life (QOL) of nonmotor symptoms (NMS) of the tremor dominant (TD) and...
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Motor and non-motor outcome in tremor dominant Parkinson’s disease after MR-guided focused ultrasound thalamotomy
Background and objectivesMagnetic Resonance-guided Focused Ultrasound (MRgFUS) is an emerging technique for the treatment of severe,...
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Hearing dysfunction heralds an increase in non-motor burden and a worse quality of life in Parkinson’s disease: new insights from non-motor spectrum
BackgroundSensorial non-motor symptoms (NMSs) in Parkinson’s disease (PD) still lack appropriate investigation in clinical practice.
This study aimed...
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Neuromuscular junction involvement in inherited motor neuropathies: genetic heterogeneity and effect of oral salbutamol treatment
ObjectivesInherited defects of the neuromuscular junction (NMJ) comprise an increasingly diverse range of diseases. Several recently identified genes...
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Novel and experimental therapeutics for the management of motor and non-motor Parkinsonian symptoms
BackgroundBoth motor and non-motor symptoms of Parkinson’s disease (PD) have a substantial detrimental influence on the patient’s quality of life....
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Differential neurocognitive profiles in adult attention-deficit/hyperactivity disorder subtypes revealed by the Cambridge Neuropsychological Test Automated Battery
Adult attention-deficit/hyperactivity disorder (aADHD) represents a heterogeneous entity incorporating different subgroups in terms of...
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Subtypes in addiction and their neurobehavioral profiles across three functional domains
Rates of return to use in addiction treatment remain high. We argue that the development of improved treatment options will require advanced...
