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Rapid antigen-based and rapid molecular tests for the detection of SARS-CoV-2: a rapid review with network meta-analysis of diagnostic test accuracy studies
BackgroundThe global spread of COVID-19 created an explosion in rapid tests with results in < 1 hour, but their relative performance characteristics...
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Specificity of serological screening tests and reference laboratory tests to diagnose gambiense human African trypanosomiasis: a prospective clinical performance study
BackgroundSerological screening tests play a crucial role to diagnose gambiense human African trypanosomiasis (gHAT). Presently, they preselect...
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Histopathological Evaluation and Molecular Diagnostic Tests for Peritoneal Metastases with Unknown Primary Site—a Review
Cancer of unknown primary (CUP) is a well-studied entity with guidelines available for the management of patients with CUP. The peritoneum represents...
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Molecular Surgical Pathology
Since the first edition of this book in 2012, the field of molecular pathology has expanded exponentially. The advent of complete cancer genome...
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Impact of molecular diagnostic tests on diagnostic and treatment delays in tuberculosis: a systematic review and meta-analysis
BackgroundCountries with high TB burden have expanded access to molecular diagnostic tests. However, their impact on reducing delays in TB diagnosis...
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Explaining multivariate molecular diagnostic tests via Shapley values
BackgroundMachine learning (ML) can be an effective tool to extract information from attribute-rich molecular datasets for the generation of...
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Clinical characteristics and the diagnostic role of molecular tests in musculoskeletal infections caused by nontuberculous Mycobacterium: a single-center experience
PurposeWe retrospectively investigated NTM musculoskeletal infections to understand the clinical characteristics as well as the diagnostic...
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Usefulness of rapid molecular tests in pediatric respiratory tract infections
ObjectiveTo evaluate the role and the advantages of nasopharyngeal swabs in the detection of Influenza A and B viruses and Respiratory syncytial...
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Molecular testing for thyroid nodules: Where are we now?
Approximately 25% of the fine needle aspiration samples (FNAB) of thyroid nodules are classified as “indeterminate samples”, that means, Bethesda III...
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Evaluation of ECLIA antigen detection tests as screening methods for COVID-19 in comparison with molecular analysis
BackgroundData from literature shows that antigen tests are rapid and helpful tools for diagnosis of COVID-19.
AimThis work aimed to evaluate the...
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Detection of sensitivity and vestigiality of presumptive tests for swabbed blood stains
It is a common practice in forensic casework to use presumptive tests for blood stains before DNA extraction and testing. Stains are usually swabbed...
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Use of Epicutaneous Tests in the Study of Drug Allergy
Purpose of ReviewEpicutaneous or patch tests (PT) are a common diagnostic tool in the study of adverse skin reactions related to the topical or...
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The role of molecular diagnosis in anaphylactic patients with dual or triple-sensitization to Hymenoptera venoms
BackgroundThe poly-sensitization to Hymenoptera venom makes it difficult to select genuine allergens for immunotherapy and increases patients’ costs....
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A retrospective study of accuracy and usefulness of electrophysiological exercise tests
ObjectivesThis study aimed to determine the usefulness of electrophysiological exercise tests. The significance of slightly abnormal exercise tests...
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Performance of intraoperative neurocognitive tests during awake surgery for patients with diffuse low-grade glioma
Despite great advancements and the diffusion of awake surgery for brain tumors, the literature shows that the tests applied during the procedure are...
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Liver tests: what to measure and what to do when abnormal
Liver diseases are frequent and silent. Physicians have to look for them. To do this several tests are available. This article reviews how to use...
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Cost-effectiveness analysis of COVID-19 tests in the unified health system
BackgroundTo evaluate the cost-effectiveness ratio and economic impact of the Rapid Antigen Test (TR-Ag) to replace RT-PCR for the detection of the...
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Digital counting of tissue cells for molecular analysis: the QuANTUM pipeline
The estimation of tumor cellular fraction (TCF) is a crucial step in predictive molecular pathology, representing an entry adequacy criterion also in...
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Guidelines for molecular testing in non-small cell lung cancer – recommendations from the Brazilian Society of Pathology
The Brazilian Society of Pathology Guidelines project aims to provide recommendations for clinicians and pathologists based on the best available...
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Screening for PTSD and TBI in Veterans using Routine Clinical Laboratory Blood Tests
Post-traumatic stress disorder (PTSD) is a mental disorder diagnosed by clinical interviews, self-report measures and neuropsychological testing....
