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MAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1
Dynamin-related protein 1 (Drp1) is a crucial regulator of mitochondrial dynamics, the overactivation of which can lead to cardiovascular disease....
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Percutaneous radiofrequency thermocoagulation and microvascular decompression for treating glossopharyngeal neuralgia: a retrospective clinical study
ObjectivesThis study aimed to investigate the differences in the effectiveness of percutaneous radiofrequency thermocoagulation (PRT) and...
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Endothelial MICU1 alleviates diabetic cardiomyopathy by attenuating nitrative stress-mediated cardiac microvascular injury
BackgroundMyocardial microvascular injury is the key event in early diabetic heart disease. The injury of myocardial microvascular endothelial cells...
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Endothelial ILK induces cardioprotection by preventing coronary microvascular dysfunction and endothelial-to-mesenchymal transition
Endothelial dysfunction is an early event in coronary microvascular disease. Integrin-linked kinase (ILK) prevents endothelial nitric oxide synthase...
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Phenotype-based management of coronary microvascular dysfunction
40-70% of patients undergoing invasive coronary angiography with signs and symptoms of ischemia are found to have no obstructive coronary artery...
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Microvascular decompression for hemifacial spasm after Bell’s palsy: a retrospective clinical study
ObjectiveThis study aimed to investigate the clinical characteristics of hemifacial spasm (HFS) after Bell’s palsy and to evaluate the therapeutic...
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Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis
BackgroundEmpagliflozin has been reported to protect endothelial cell function, regardless of diabetes status. However, the role of empagliflozin in...
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Use superb microvascular imaging to diagnose and predict metastatic cervical lymph nodes in patients with papillary thyroid carcinoma
PurposePapillary thyroid carcinoma (PTC) with metastatic lymph nodes (LNs) is closely associated with disease recurrence. This study accessed the...
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Insight into microvascular adaptive alterations in the Glisson system of biliary atresia after Kasai portoenterostomy using X-ray phase-contrast CT
ObjectivesTo investigate microvascular alterations in the Glisson system of biliary atresia (BA) patients after Kasai portoenterostomy (KP) using...
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Toll like receptor 4 gene Asp299Gly polymorphism increases the risk of diabetic microvascular complications: a meta analysis
ObjectiveThe relationship between Toll like receptor 4(TLR4) gene Asp299Gly polymorphism and diabetic microvascular complications (DMI) is unclear....
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Combined associations of visceral adipose tissue and adherence to a Mediterranean lifestyle with T2D and diabetic microvascular complications among individuals with prediabetes
BackgroundIt’s unclear if excess visceral adipose tissue (VAT) mass in individuals with prediabetes can be countered by adherence to a Mediterranean...
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Clinical application of intraoperative ultrasound superb microvascular imaging in brain tumors resections: contributing to the achievement of total tumoral resection
BackgroundTo investigate whether the intraoperative superb microvascular imaging(SMI) technique helps evaluate lesion boundaries compared with...
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Coronary Microvascular Dysfunction: A Practical Approach to Diagnosis and Management
Purpose of ReviewThe purpose of this review is to provide an overview of diagnostic and treatment considerations in patients with coronary...
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Periodontal diseases assessed by average bone resorption are associated with microvascular complications in patients with type 2 diabetes
Periodontal disease often develops in patients with diabetes, and further exacerbated with diabetic complications. It would be clinically important...
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Early microvascular coronary endothelial dysfunction precedes pembrolizumab-induced cardiotoxicity. Preventive role of high dose of atorvastatin
Immune checkpoint inhibitors (ICIs) exhibit remarkable antitumor activity and immune-related cardiotoxicity of unknown pathomechanism. The aim of the...
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A non-interventional study of microcirculation dynamics in allogeneic hematopoietic cell transplantation survivors compared to controls: evidence of impaired microvascular response regardless of conventional cardiovascular risk factors
Allogeneic hematopoietic cell transplantation (alloHCT) survivors have been recently recognized as patients at increased cardiovascular risk. We...
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Preoperative application of systemic inflammatory biomarkers combined with MR imaging features in predicting microvascular invasion of hepatocellular carcinoma
PurposeTo investigate whether systemic inflammatory biomarkers compared with the imaging features interpreted by radiologists can offer complementary...
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An advanced ultrasound application used to assess peripheral vascular diseases: superb microvascular imaging
Over the past several years, a novel ultrasound imaging modality termed superb microvascular imaging (SMI) has enabled visualization of microvessels....
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Expert consensus on the management of infusion-related reactions (IRRs) in patients with sickle cell disease (SCD) receiving crizanlizumab: a RAND/UCLA modified Delphi panel
Crizanlizumab, a monoclonal antibody against P-selectin, has been shown to reduce vaso-occlusive crises (VOCs) compared to placebo in patients ≥ 16...
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Effects of a single aerobic exercise on perfused boundary region and microvascular perfusion: a field study
The endothelium and the glycocalyx play a pivotal role in regulating microvascular function and perfusion in health and critical illness. It is...
