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MicroCT and Histological Analysis of Clot Composition in Acute Ischemic Stroke
PurposeAssessing clot composition on prethrombectomy computed tomography (CT) imaging may help in stroke treatment planning. In this study we seek to...
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A microCT-based platform to quantify drug targeting
BackgroundHeterotopic ossification (HO) is a frequent and debilitating complication of traumatic musculoskeletal injuries and orthopedic procedures....
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Quantitative Evaluation of the 3D Anatomy of the Human Osseous Spiral Lamina Using MicroCT
PurposeThe osseous spiral lamina (OSL) is an inner cochlear bony structure that projects from the modiolus from base to apex, separating the cochlear...
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Finite-Element Modelling Based on Optical Coherence Tomography and Corresponding X-ray MicroCT Data for Three Human Middle Ears
PurposeOptical coherence tomography (OCT) is an emerging imaging modality which is non-invasive, can be employed in vivo, and can record both anatomy...
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Analysis of tympanic sinus shape for purposes of intraoperative hearing monitoring: a microCT study
PurposeSinus tympani is the space in the retrotympanum, with variable morphology. Computed tomography is a common tool to investigate sinus tympani...
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Development and characterization of a predictive microCT-based non-union model in Fischer F344 rats
IntroductionNon-unions remain a clinical problem and are characterised by the failure to heal after a defined period of time. Current preclinical...
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Detection and assessment of capsular invasion, vascular invasion and lymph node metastasis volume in thyroid carcinoma using microCT scanning of paraffin tissue blocks (3D whole block imaging): a proof of concept
In the modern era, detailed pathologic characteristics of a thyroid tumor are crucial to achieve accurate diagnosis and guide treatment. The presence...
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Comparison of histomorphometry and microCT after sinus augmentation using xenografts of different particle sizes in rabbits
PurposeThe aim of the present experiment was to compare the data on new bone formation measured histologically and microtomographically in maxillary...
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Effects of boric acid on alveolar sockets filling after dental extraction in rats
PurposeAfter extraction, dental alveolus filling aims to reduce bone loss and maintain the alveolus volume during patient rehabilitation. Boric acid...
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Influence of the use of autogenous bone particles to close the access window after maxillary sinus floor augmentation: a micro‐computed tomography and positron emission tomography study in rabbits
AimThe purpose of this study was to evaluate using microCT and positron emission tomography (PET) analysis, the influence on bone healing of the...
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Early removal of the infrapatellar fat pad/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs
BackgroundThe infrapatellar fat pad (IFP) is the largest adipose deposit in the knee; however, its contributions to the homeostasis of this organ...
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Tantalum oxide nanoparticles as versatile and high-resolution X-ray contrast agent for intraductal image-guided ablative procedure in rodent models of breast cancer
There are limited options for primary prevention of breast cancer (BC). Experimental procedures to locally prevent BC have shown therapeutic efficacy...
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Amniotic suspension allograft improves pain and function in a rat meniscal tear-induced osteoarthritis model
BackgroundOsteoarthritis is a degenerative disease of the knee that affects 250 million people worldwide. Due to the rising incidence of knee...
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Cardiac structure discontinuities revealed by ex-vivo microstructural characterization. A focus on the basal inferoseptal left ventricle region
BackgroundWhile the microstructure of the left ventricle (LV) has been largely described, only a few studies investigated the right ventricular...
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Early, non-invasive detection of radiation-induced lung injury using PET/CT by targeting CXCR4
PurposeRadiation-induced lung injury (RILI) is a severe side effect of radiotherapy (RT) for thoracic malignancies and we currently lack established...
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Lugol’s solution but not formaldehyde affects bone microstructure and bone mineral density parameters at the insertion site of the rotator cuff in rats
BackgroundThis study aimed to investigate whether rodent shoulder specimens fixed in formaldehyde for histological and histomorphometric...
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Human Cadaveric Model for Vessel Preparation Device Testing in Calcified Tibial Arteries
To describe an ex vivo model for vessel preparation device testing in tibial arteries. We performed orbital atherectomy (OA), intravascular...
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Comparison of synthetic ceramic products formulated with autologous blood coagulum containing rhBMP6 for induction of bone formation
PurposeOsteogrow, an osteoinductive device containing recombinant human Bone Morphogenetic Protein 6 (rhBMP6) in autologous blood coagulum, is a...
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Pneumococcal Meningitis Induces Hearing Loss and Cochlear Ossification Modulated by Chemokine Receptors CX3CR1 and CCR2
PurposePneumococcal meningitis is a major cause of hearing loss and permanent neurological impairment despite widely available antimicrobial...
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Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis
BackgroundThis study aims to investigate the potential anti-inflammatory effects of exosomes engineered to carry super-repressor IκB (Exo-srIκB), an...
