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Trastuzumab deruxtecan for human epidermal growth factor receptor 2-low advanced or metastatic breast cancer: recommendations from the Japanese Breast Cancer Society Clinical Practice Guidelines
The Japanese Breast Cancer Society Clinical Practice Guidelines are published as timely guidance on clinical issues in breast cancer treatment in...
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Metastatic Triple-Negative Breast Cancer
Purpose of ReviewTriple-negative breast cancer (TNBC) is a heterogeneous disease group with a known aggressive phenotype and poor prognosis. To date,...
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Genetic Testing in Metastatic Breast Cancer in the USA: A Podcast
This podcast highlights the importance of genetic testing in patients with metastatic breast cancer, with a specific focus on germline or inherited...
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Outcomes for breast cancer survivors with metastatic disease in a physical activity program for medically underserved cancer survivors
PurposeThis study examined the effectiveness and feasibility of the Active Living After Cancer (ALAC) program for metastatic breast cancer (MBC)...
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De novo versus recurrent metastatic breast cancer affects the extent of brain metastases
PurposeWe aimed to identify factors associated with the extent of brain metastases in patients with breast cancer to help distinguish brain...
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Sacituzumab Govitecan: A Review in Unresectable or Metastatic HR+/HER2− Breast Cancer
Sacituzumab govitecan (TRODELVY ® ) is a first-in-class trophoblast cell-surface antigen 2 (Trop-2)–directed antibody and topoisomerase I inhibitor...
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RON-augmented cholesterol biosynthesis in breast cancer metastatic progression and recurrence
Recurrence remains a significant clinical barrier to improving breast cancer patient outcomes. The RON receptor is a predictor of metastatic...
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Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer
Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go through successive steps,...
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Cardiotoxicities of Non-Chemotherapeutic Metastatic Breast Cancer Treatments
Purpose of ReviewAlthough mortality rates have declined significantly in recent years, breast cancer remains the second most common cause of cancer...
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Surgery in the Setting of Metastatic Breast Cancer
Purpose of ReviewAmong individuals with metastatic breast cancer, surgical resection of the primary tumor remains controversial, and its benefit is...
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Efficacy of Lapatinib Plus Capecitabine After TDM-1 in HER2-Positive Metastatic Breast Cancer Patients
Different targeted therapy options exist for treating HER2-positive metastatic breast cancer patients. This study evaluated the efficacy and...
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Tolerability and effectiveness of palbociclib in older women with metastatic breast cancer
PurposePalbociclib has become the standard of care for estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 negative (HER2-)...
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Plasma apolipoprotein M predicts overall survival in metastatic breast cancer patients
PurposeApolipoprotein M (APOM) is a plasma apolipoprotein closely involved with lipid metabolism and inflammation. In vitro studies suggest that APOM...
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Updated Austrian treatment algorithm for metastatic triple-negative breast cancer
Approximately 15% of newly diagnosed breast cancer patients have neither hormone receptors expression nor HER2 overexpression and/or HER2/neu gene...
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Tumor heterogeneity and clinically invisible micrometastases in metastatic breast cancer—a call for enhanced surveillance strategies
The biology of metastatic breast cancer (MBC) is understudied, primarily due to the difficulty of procuring multiple samples from patients with...
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Imaging in metastatic breast cancer, CT, PET/CT, MRI, WB-DWI, CCA: review and new perspectives
BackgroundBreast cancer is the most frequent cancer in women and remains the second leading cause of death in Western countries. It represents a...
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Predicting three or more metastatic nodes using contrast-enhanced lymphatic US findings in early breast cancer
ObjectivesTo develop and validate a nomogram for predicting ≥ 3 metastatic axillary lymph nodes (ALNs) in early breast cancer with no palpable...
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Evaluation of markers of immunity in different metastatic immune microenvironments suggests more suppression within breast to liver metastases in breast cancer
PurposeProgrammed death receptor ligand-1 (PD-L1) expression and tumor mutational burden (TMB) are approved screening biomarkers for immune...
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Re-imagining metastatic breast cancer care delivery: a patient-partnered qualitative study
PurposeWhile significant progress in metastatic breast cancer (MBC) treatment has prolonged survival and improved prognosis, there remain substantial...
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A whole-food, plant-based randomized controlled trial in metastatic breast cancer: weight, cardiometabolic, and hormonal outcomes
PurposeBreast cancer treatment is associated with weight gain, and obesity and its related cardiometabolic and hormonal risk factors have been...
