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Metabolically healthy obesity: from epidemiology and mechanisms to clinical implications
The concept of metabolic health, particularly in obesity, has attracted a lot of attention in the scientific community, and is being increasingly...
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Distinguishing health-related parameters between metabolically healthy and metabolically unhealthy obesity in women
BackgroundObesity represents a global health crisis, yet a dichotomy is emerging with classification according to the metabolic state into...
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Conversions between metabolically unhealthy and healthy obesity from midlife to late-life
IntroductionMetabolically healthy obesity may be a transient phenotype, but studies with long follow-up, especially covering late-life, are lacking....
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Metabolically Healthy Obesity: Are Interventions Useful?
Purpose of ReviewThis review aims to detail the current global research state of metabolically healthy obesogenesis with regard to metabolic factors,...
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Metabolically healthy obesity and risks of cardiovascular disease and all-cause mortality, a matched cohort study: the Shizuoka study
BackgroundMetabolically healthy obesity is not always a benign condition. It is associated with an increased incidence of cardiovascular disease and...
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Kidney damage predictors in children with metabolically healthy and metabolically unhealthy obesity phenotype
BackgroundObesity and kidney damage have been closely linked in adults, but little is still known in childhood.
ObjectiveTo identify predictors of...
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Association between metabolically healthy overweight/obesity and gallstones in Chinese adults
BackgroundMetabolic syndrome and obesity are risk factors for gallstones. However, these two factors often occur together, and few studies have...
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Quality of life and psychosocial outcomes among children with metabolically healthy and unhealthy obesity
BackgroundObesity and obesity-related morbidities are associated with poor psychosocial adjustment and health-related quality of life (HRQoL). This...
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Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes
BackgroundPeople with metabolically healthy (MHO) and metabolically unhealthy obesity (MUO) differ for the presence or absence of cardio-metabolic...
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Association of metabolically healthy obesity in young adulthood with myocardial structure and function
BackgroundObesity is major cause of cardiovascular diseases. Metabolically healthy obesity (MHO) may increase heart failure risk early in life, and...
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The triglycerides and glucose index is more strongly associated with metabolically healthy obesity phenotype than the lipid and obesity indices
PurposeThe triglycerides and glucose (TyG) index is a reliable biomarker for estimating insulin resistance; however, evidence regarding the use of...
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Diagnostic accuracy of anthropometric indices for metabolically healthy obesity in child and adolescent population
BackgroundA variable percentage of children and adolescents with obesity do not have cardiometabolic comorbidities. A phenotype called metabolically...
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Integrated genetic and epigenetic analyses uncovered GLP1R association with metabolically healthy obesity
BackgroundBoth genetic and epigenetic variations of GLP1R influence the development and progression of obesity. However, the underlying mechanism...
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Predictive markers of metabolically healthy obesity in children and adolescents: can AST/ALT ratio serve as a simple and reliable diagnostic indicator?
This study aimed to estimate the prevalence of metabolically healthy obesity (MHO) according to two different consensus-based criteria and to...
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Cardiovascular risk of metabolically healthy obesity in two european populations: Prevention potential from a metabolomic study
BackgroundA new definition of metabolically healthy obesity (MHO) has recently been proposed to stratify the heterogeneous mortality risk of obesity....
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Association between metabolically healthy obesity and non-alcoholic fatty liver disease
BackgroundThe risks of NAFLD and NAFLD with fibrosis progression among metabolically healthy obesity (MHO) individuals are largely unexplored. This...
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Exploring metabolically healthy obesity: prevalence, characteristics, and cardiovascular risk in the Iranian population based on the STEPS 2021
BackgroundRegarding the rapidly increasing prevalence of obesity throughout the globe, it remains a serious public health concern. A subgroup of...
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Relationship between metabolically healthy obesity and the development of hypertension: a nationwide population-based study
BackgroundMetabolically healthy obesity (MHO), has been recognized as a transient phenotype with few cardiometabolic diseases; however, little is...
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Impact of bariatric surgery on carotid intima-media thickness and arterial stiffness in metabolically healthy obesity: a prospective study
PurposeCardiovascular disease is one of the leading causes of mortality in patients with obesity. Metabolically healthy obesity (MHO), in which...
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Improvement of Low-Grade Inflammation in Patients with Metabolically Healthy Severe Obesity After Primary Bariatric Surgery
IntroductionThe inflammatory state that accompanies adiposity and the metabolic syndrome (MetS) is called “low-grade” inflammation. White blood cell...
