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Intra- and interobserver reliability analysis of pediatric lower limb parameters on digital long leg radiographs
BackgroundMalalignments of the lower extremity are common reasons for orthopedic consultation because it may lead to osteoarthritis in adulthood. An...
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Artificial intelligence-based analyses of varus leg alignment and after high tibial osteotomy show high accuracy and reproducibility
PurposeThe aim of this study was to investigate the performance of an artificial intelligence (AI)-based software for fully automated analysis of leg...
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Mutant-allele dispersion correlates with prognosis risk in patients with advanced non-small cell lung cancer
BackgroundIntra-tumor heterogeneity (ITH) contributes to lung cancer progression and resistance to therapy. To evaluate ITH and determine whether it...
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Whole-tumor amide proton transfer–weighted imaging histogram analysis to predict pathological extramural venous invasion in rectal adenocarcinoma: a preliminary study
ObjectivesTo evaluate amide proton transfer–weighted (APTw)–derived whole-tumor histogram analysis parameters in predicting pathological extramural...
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Physical activity cut-points for older adults using the Zio XT onboard accelerometer
IntroductionThe Zio® XT continuous ambulatory electrocardiographic monitor (Zio) contains an accelerometer that can help quantify an individual’s...
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A wide range of missing imputation approaches in longitudinal data: a simulation study and real data analysis
BackgroundMissing data is a pervasive problem in longitudinal data analysis. Several single-imputation (SI) and multiple-imputation (MI) approaches...
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Assessment of equations estimating average glucose among patients with diabetic kidney disease before dialysis
ObjectiveEstimation of average glucose (AG) from hemoglobin A1c (HbA1c) helps guide diabetes management, and thus several AG-HbA1c equations have...
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Mitral annular disjunction in surgical mitral valve prolapse: prevalence, characteristics and outcomes
BackgroundThere is a paucity of literature regarding outcomes of patients with mitral valve prolapse (MVP) and mitral annular disjunction (MAD) after...
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A Phase 1, randomized, double-blind, placebo-controlled, single- and multiple-dose escalation study to evaluate the safety and pharmacokinetics/pharmacodynamics of PF-06835375, a C-X-C chemokine receptor type 5 directed antibody, in patients with systemic lupus erythematosus or rheumatoid arthritis
BackgroundThe objective of this study was to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF‑06835375, a potent...
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Prediction of daily mean and one-hour maximum PM2.5 concentrations and applications in Central Mexico using satellite-based machine-learning models
BackgroundMachine-learning algorithms are becoming popular techniques to predict ambient air PM 2.5 concentrations at high spatial resolutions...
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Whole-lesion apparent diffusion coefficient (ADC) histogram as a quantitative biomarker to preoperatively differentiate stage IA endometrial carcinoma from benign endometrial lesions
BackgroundTo assess the value of whole-lesion apparent diffusion coefficient (ADC) histogram analysis in differentiating stage IA endometrial...
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Association of intraindividual tacrolimus variability with de novo donor-specific HLA antibody development and allograft rejection in pediatric kidney transplant recipients with low immunological risk
BackgroundTacrolimus (Tac) intraindividual variability (TacIPV) in pediatric kidney transplant patients is only poorly understood. We investigated...
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Flash glucose monitoring system in gestational diabetes: a study of accuracy and usability
PurposeStudies of flash glucose monitoring systems (FGMSs) in pregnancy are insufficient, especially in gestational diabetes (GD). Our aim was to...
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“Won’t get fooled again”: statistical fault detection in COVID-19 Latin American data
BackgroundClaims of inconsistency in epidemiological data have emerged for both developed and develo** countries during the COVID-19 pandemic.
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Plasma Mitochondrial DNA Clearance by Continuous Venovenous Haemofiltration in Critically Ill Patients
ObjectiveMitochondrial DNA (mtDNA) reportedly has diagnostic and predictive value in critically ill patients. This study evaluated the diagnostic and...
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The VRF-L and VRF-GL IOL power calculation methods after radial keratotomy
BackgroundTo investigate the accuracy of the VRF-L and VRF-GL IOL power calculation methods in cataract surgery after radial keratotomy (RK).
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Towards standardization of absolute SPECT/CT quantification: a multi-center and multi-vendor phantom study
AbstractAbsolute quantification of radiotracer distribution using SPECT/CT imaging is of great importance for dosimetry aimed at personalized...
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CT-based radiomics can identify physiological modifications of bone structure related to subjects’ age and sex
PurposeRadiomics of vertebral bone structure is a promising technique for identification of osteoporosis. We aimed at assessing the accuracy of...
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Accuracy of 20 Intraocular Lens Power Calculation Formulas in Medium-Long Eyes
IntroductionThe aim of this work is to compare 20 intraocular lens (IOL) power calculation formulas in medium-long eyes (24.50–25.99 mm) in terms of...
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Scoring PD-L1 Expression in Urothelial Carcinoma: An International Multi-Institutional Study on Comparison of Manual and Artificial Intelligence Measurement Model (AIM-PD-L1) Pathology Assessments
Assessing programmed death ligand 1 (PD-L1) expression on tumor cells (TCs) using Food and Drug Administration-approved, validated immunoassays can...
