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Methamphetamine: Mechanism of Action and Chinese Herbal Medicine Treatment for Its Addiction
With the proliferation of synthetic drugs, research on the mechanism of action of addictive drugs and treatment methods is of great significance....
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Mechanism of action, resistance, interaction, pharmacokinetics, pharmacodynamics, and safety of fostemsavir
The Food and Drug Administration (FDA) has licensed many antiretroviral medications to treat human immunodeficiency virus type 1 (HIV-1), however,...
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Ketamine’s mechanism of action with an emphasis on neuroimmune regulation: can the complement system complement ketamine’s antidepressant effects?
Over 300 million people worldwide suffer from major depressive disorder (MDD). Unfortunately, only 30–40% of patients with MDD achieve complete...
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Mechanism of action and treatment of type I interferon in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) caused by HBV, HCV infection, and other factors is one of the most common malignancies in the world. Although,...
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Interferons in vitreoretinal diseases; a review on their clinical application, and mechanism of action
PurposeThis review investigates the therapeutic benefits of interferons (IFNs) in vitreoretinal diseases, focusing on their regulatory roles in...
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Mechanism of Action of Temporary Peripheral Nerve Stimulation
Purpose of ReviewPeripheral nerve stimulation (PNS) refers to the technique of utilizing electrical stimulation of peripheral nerves to inhibit the...
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Study on the mechanism of action of Wu Mei Pill in inhibiting rheumatoid arthritis through TLR4-NF-κB pathway
BackgroundWu Mei Pills (WMP) is a traditional Chinese medication that exhibits considerable anti-inflammatory effects. While WMP has been documented...
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Using network pharmacological analysis and molecular docking to investigate the mechanism of action of quercetin’s suppression of oral cancer
ObjectiveThis investigation seeks to explore the mechanism of quercetin in oral cancer by incorporating network pharmacology analysis and molecular...
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The prevalence, mechanism of action, and toxicity of Nigerian psychoactive plants
Cannabis sativa, Datura stramonium, Nicotiana tabacum, and Carica papaya are plants that naturally grow in Nigeria. They are reportedly rich in...
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Anticancer perspective of 6-shogaol: anticancer properties, mechanism of action, synergism and delivery system
Cancer is a malignant disease that has plagued human beings all the time, but the treatment effect of commonly used anticancer drugs in clinical...
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Effectiveness and mechanism of action of rTMS combined with quadriceps strength training in individuals with knee osteoarthritis: study protocol for a randomized controlled trial
BackgroundQuadriceps training is necessary in function and activity of daily living for patients with knee osteoarthritis (KOA). However, it did not...
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Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of Action
Estetrol (E4) is the most recently described natural estrogen. It is produced by the human fetal liver during pregnancy and its physiological...
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In vitro anti-yeast activity, kinetics and mechanism of action of essential oils from two cameroonian medicinal plants
BackgroundTreatment of Candida infections have become increasingly difficult due to antifungal drug resistance, which has drawn attention toward the...
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Mechanism of action of genicular artery embolization in a rabbit model of knee osteoarthritis
ObjectivesTo establish a rabbit osteoarthritis model for genicular artery embolization (GAE) experiments and to investigate the cellular mechanism of...
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Mechanism of Action of Peripheral Nerve Stimulation
Purpose of ReviewThe number of applications for peripheral nerve stimulation (PNS) in the pain management field is ever-growing. With the increasing...
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Elucidating the antifungal activity and mechanism of action of bioactive phytochemicals against fungal dermatitis isolates
Dermatophytosis has been the most common cause of superficial fungal infections which invade the keratinized tissues of body such as nail, hair, and...
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Identifying the mechanism of action of the Kv7 channel opener, retigabine in the treatment of epilepsy
Epilepsy is characterized by recurrent epileptic seizures caused by high levels of neuronal excitability in the brain. Voltage-sensitive K+ channels...
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Molecular Characterisation of the Mechanism of Action of Stimulant Drugs Lisdexamfetamine and Methylphenidate on ADHD Neurobiology: A Review
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset neurodevelopmental disorder characterised by persistent inattention,...
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Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein
BackgroundRhein can significantly delay the progression of chronic nephropathy. However, its mechanism of action has not been adequately elaborated,...
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Koetjapic acid: unveiling its potential as a saviour in the realm of biological and medicinal properties, with a focus on anticancer mechanism of action
Scientists have been compelled to search for alternative treatments due to the increasing prevalence of chemoresistance as well as the agonising and...
