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  1. Updates in Management of Malignant Pleural Mesothelioma

    Malignant pleural mesothelioma (MPM) is an aggressive asbestos-associated thoracic malignancy that is usually incurable. As demonstrated in the...

    Alexius John, Hazel O’Sullivan, Sanjay Popat in Current Treatment Options in Oncology
    Article 17 November 2023
  2. Malignant Pleural Mesothelioma: Staging and Radiological Response Criteria in Patients Treated with Immune Checkpoint Inhibitors

    Malignant pleural mesothelioma (MPM) is a rare and challenging cancer associated with asbestos fiber exposure, which offers limited treatment...

    Serafina Martella, Marco Maria Aiello, ... Michele Porcu in Targeted Oncology
    Article 08 December 2023
  3. Malignant Sarcomatoid Pleural Mesothelioma Presenting as a Chest Wall Tumor

    Malignant mesothelioma is a rare and aggressive neoplasm with a median survival of less than 12 months and a 5-year survival rate of less than 5%....

    Chemuru Munisekhar Reddy, H. V. Rajashekara Reddy in Indian Journal of Surgery
    Article 30 August 2022
  4. Optimal surgery for resectable malignant pleural mesothelioma in the setting of multimodality treatment

    The surgical treatment of malignant pleural mesothelioma (MPM) involves procedures to achieve macroscopic complete resection, depending on the...

    Nobuyuki Kondo, Seiki Hasegawa in Surgery Today
    Article Open access 20 July 2023
  5. The Evolving Therapeutic Landscape for Malignant Pleural Mesothelioma

    Purpose of Review

    For patients with malignant pleural mesothelioma, prognosis is poor with extremely low 5-year survival rates and limited therapeutic...

    Nirosha D. Perera, Aaron S. Mansfield in Current Oncology Reports
    Article 03 June 2022
  6. Treatment patterns and humanistic burden of malignant pleural mesothelioma in Spain

    Purpose

    Malignant pleural mesothelioma (MPM) is an aggressive cancer with long latency and poor prognosis. The real-world treatment patterns and...

    Susana Cedres, Julio Calvete, ... Melinda Daumont in Clinical and Translational Oncology
    Article Open access 06 July 2024
  7. Molecular Alterations in Malignant Pleural Mesothelioma: A Hope for Effective Treatment by Targeting YAP

    Malignant pleural mesothelioma is a rare and aggressive neoplasm, which has primarily been attributed to the exposure to asbestos fibers (83% of...

    Fatéméh Dubois, Céline Bazille, ... Guénaëlle Levallet in Targeted Oncology
    Article Open access 30 July 2022
  8. Sarcomatoid malignant pleural mesothelioma: a case of long-term recurrence-free survival following curative intent surgery alone

    Background

    Curative intent surgery may be indicated for some patients with resectable early stage malignant pleural mesothelioma (MPM). However,...

    Masatoshi Kanayama, Masaru Takenaka, ... Fumihiro Tanaka in Surgical Case Reports
    Article Open access 31 May 2024
  9. Impact of Pleural Thickness on Occurrence of Postoperative Complications in Patients with Malignant Pleural Mesothelioma

    Objectives

    The rates of postoperative mortality and morbidity are high in patients with malignant pleural mesothelioma (MPM). Therefore, it is...

    Toshinari Ito, Shota Nakamura, ... Toyofumi Fengshi Chen-Yoshikawa in Annals of Surgical Oncology
    Article 13 November 2022
  10. Genetic analysis of familial predisposition in the pathogenesis of malignant pleural mesothelioma

    Purpose

    Mesothelioma is the primary tumor of the mesothelial cell membrane. The most important etiology is asbestos exposure. The development of...

    Muhittin Akarsu, Güntülü Ak, ... Muzaffer Metintaş in Journal of Cancer Research and Clinical Oncology
    Article 07 April 2023
  11. Safety and efficacy of helical tomotherapy following lung-sparing surgery in locally advanced malignant pleural mesothelioma

    Purpose

    To assess the value of radiation therapy (RT) with helical tomotherapy (HT) in the management of locally advanced malignant pleural...

    Julian P. Layer, Pascal Fischer, ... Christina Leitzen in Strahlentherapie und Onkologie
    Article Open access 22 November 2023
  12. Development of Patient and Caregiver Conceptual Models Investigating the Health-Related Quality of Life Impacts of Malignant Pleural Mesothelioma

    Background

    Malignant pleural mesothelioma (MPM) is a rare and usually fatal malignancy frequently linked to occupational asbestos exposures and...

    Adam E. J. Gibson, Waqas Ahmed, ... Liz Darlison in The Patient - Patient-Centered Outcomes Research
    Article 15 April 2024
  13. Biphasic pleural mesothelioma treated successfully with multimodal therapy: a case report

    Background

    Pleural mesothelioma is an aggressive malignant tumor and has a poor prognosis. In particular, biphasic pleural mesothelioma is a less...

    Kenshiro Omura, Ryuta Fukai, ... Masayuki Noguchi in General Thoracic and Cardiovascular Surgery Cases
    Article Open access 03 October 2023
  14. Malignant Pleural Mesothelioma Advances in Pathogenesis, Diagnosis, and Treatments

    This book provides essential information on recent advances in molecular genetics, epidemiology, translational research, and the latest results of...
    Book 2021
  15. Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths

    Purpose of Review

    In this article, we provide a comprehensive analysis of recent progress in the genetic characterisation of pleural mesothelioma, and...

    Alistair Nash, Jenette Creaney in Current Oncology Reports
    Article Open access 28 November 2023
  16. Immunotherapy approaches for malignant pleural mesothelioma

    Over the past decade, immune-checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer. In mesothelioma, a rare cancer with a dismal...

    Dean A. Fennell, Sean Dulloo, James Harber in Nature Reviews Clinical Oncology
    Article 01 July 2022
  17. An anoikis-based gene signature for predicting prognosis in malignant pleural mesothelioma and revealing immune infiltration

    Introduction

    Malignant pleural mesothelioma (MPM) is an aggressive, treatment-resistant tumor. Anoikis is a particular type of programmed apoptosis...

    Jiaxin Shi, Bo Peng, ... Linyou Zhang in Journal of Cancer Research and Clinical Oncology
    Article 08 July 2023
  18. A trial of intra-pleural bacterial immunotherapy in malignant pleural mesothelioma (TILT) — a randomised feasibility study using the trial within a cohort (TwiC) methodology

    Background

    Malignant pleural mesothelioma (MPM) is an aggressive thoracic malignancy with a poor prognosis. Systemic immunotherapy is an effective...

    Anna C. Bibby, Natalie Zahan-Evans, ... Nick A. Maskell in Pilot and Feasibility Studies
    Article Open access 03 September 2022
  19. Can ultrasound shear wave elastography differentiate between malignant and benign pleural effusions?

    Background

    Malignant pleural effusion is a common and unfortunately serious condition that is related to life poor quality and mortality. The majority...

    Takeya Ahmed Taymour, Libya Saleh Wasel Mohamed, ... Mohammed Raafat Abd El-Mageed in Egyptian Journal of Radiology and Nuclear Medicine
    Article Open access 23 February 2024
  20. Caregivers of patients with malignant pleural mesothelioma: who provides care, what care do they provide and what burden do they experience?

    Purpose

    There are limited data on the impact of caregiving for patients with malignant pleural mesothelioma (MPM) on the caregiver. We aimed to...

    Adam Moore, Bryan Bennett, ... Melinda J. Daumont in Quality of Life Research
    Article Open access 25 April 2023
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