Search
Search Results
-
Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
Neuroblastoma is a pediatric cancer that can present as low- or high-risk tumors (LR-NBs and HR-NBs), the latter group showing poor prognosis due to...
-
Clinical implications of myeloid malignancy‑related somatic mutations in aplastic anemia
Aplastic anemia (AA) is a potentially fatal bone marrow failure syndrome characterized by a paucity of hematopoietic stem cells and progenitor cells...
-
Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies
Impairments in protein folding in the endoplasmic reticulum (ER) lead to a condition called ER stress, which can trigger apoptosis via the...
-
In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018
A substantial proportion of patients with malignancy develop pulmonary embolism (PE), which significantly worsens the prognosis and ranks as one of...
-
Establishment of a risk classifier to predict the in-hospital death risk of nosocomial fungal infections in cancer patients
BackgroundPatients with malignancy are at a higher risk of develo** nosocomial infections. However, limited studies investigated the clinical...
-
Combining multiple cell death pathway-related risk scores to develop neuroblastoma cell death signature
PurposeCell death plays an important role in tumourigenesis and progression; nevertheless, the clinical significance of cell death-related genes in...
-
Mortality rate and causes of death in papillary thyroid microcarcinoma
PurposePapillary thyroid microcarcinoma (PTMC) has an excellent prognosis; however, some PTMCs exhibit poor outcomes. Cancer-specific death from PTMC...
-
Causes of death after testicular cancer diagnosis: a US population-based analysis
BackgroundAfter the introduction of cisplatin-based chemotherapy, the survival time of testicular cancer (TC) patients has improved dramatically....
-
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy
Cancer cell growth, metastasis, and drug resistance pose significant challenges in the management of lung adenocarcinoma (LUAD). However, there is a...
-
Regulated cell death pathways in kidney disease
Disorders of cell number that result from an imbalance between the death of parenchymal cells and the proliferation or recruitment of maladaptive...
-
Performance of postmortem CT in the diagnosis of natural death from out-of-hospital cardiac arrest
PurposePostmortem CT (PMCT) is used widely to identify the cause of death. However, its diagnostic performance in cases of natural death from...
-
Immunogenic cell death in colorectal cancer: a review of mechanisms and clinical utility
Colorectal cancer (CRC) is a major cause of cancer-related morbidity and mortality worldwide. Despite several clinical advances the survival of...
-
Implications of different cell death patterns for prognosis and immunity in lung adenocarcinoma
In recent years, lung adenocarcinoma (LUAD) has become a focus of attention due to its low response to treatment, poor prognosis, and lack of...
-
How Primary Care Clinicians Process Patient Death: Logistics, Emotions, and Opportunities for Structural Support
BackgroundNavigating the logistics and emotional processing of a patient’s death is an inevitable part of many physicians’ roles. While research has...
-
Do regular morbidity and mortality conferences reduce preventable death rates? Our experience at Princess Marina Hospital
BackgroundThe role of morbidity and mortality conferences (M&MC) in surgical departments is to provide education and improve patient care. However,...
-
Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
-
Overcoming resistance to programmed cell death protein 1 (PD-1) blockade with allogeneic invariant natural killer T-cells (iNKT)
Gastric cancer is the 5 th most common malignancy worldwide with only 36% of patients with metastatic disease surviving beyond 5 years. Despite...
-
Choking together with aspiration of gastric contents: rare form of maternal death
BackgroundThe common causes of early postpartum maternal deaths are cardiomyopathies, obstetric hemorrhage, hypertensive disorders, and sepsis....
-
Cuproptosis as the new kryptonite of cancer: a copper-dependent novel cell death mechanism with promising implications for the treatment of hepatocellular carcinoma
Copper is an essential element for critical cellular functions such as mitochondrial respiration, cholesterol biosynthesis and immune response....
-
A bavachinin analog, D36, induces cell death by targeting both autophagy and apoptosis pathway in acute myeloid leukemia cells
PurposeAcute myeloid leukemia (AML) is an aggressive hematologic malignancy with high mortality, and it is urgent to find new and optimized treatment...
